Health and Retirement Study: Harmonized Cognitive Assessment Protocol (HCAP)

健康与退休研究：协调认知评估协议 (HCAP)

• 批准号: 10395417
• 负责人: KENNETH M LANGA
• 金额: $ 126.09万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10395417
• 关键词: Adult; Age; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; China; Cognition; Cognitive; Collaborations; Communities; Country; Data; Data Set; Dementia; Diagnostic; Elderly; England; Family; Follow-Up Studies; Future; Genome; Government; Health and Retirement Study; Home; Hour; Impaired cognition; Incidence; India; Interdisciplinary Study; International; Interview; Link; Long-Term Care; Measurement; Measures; Methods; Mexico; Participant; Personal Satisfaction; Physical Performance; Policies; Prevalence; Prevalence Study; Protocols documentation; Psychometrics; Quality of life; Reporting; Research; Research Support; Respondent; Sampling; South Africa; U-Series Cooperative Agreements; United States; Weight; aged; base; biomarker performance; care costs; cognitive function; cognitive testing; cost; diagnostic algorithm; disability; family burden; family caregiving; follow-up; genome wide association study; health economics; informant; member; middle age; mild cognitive impairment; multidisciplinary; outcome prediction; programs; trend

PROJECT SUMMARY/ABSTRACT The primary aim of the Health and Retirement Study (HRS) cooperative agreement is to collect and distribute multi-disciplinary data to support research on aging. Cognitive impairment and dementia, including Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD), impose enormous burdens on families and government policies. To provide the research community with new and richer data to study the prevalence, predictors, and outcomes of cognitive impairment and dementia, we undertook the HRS Harmonized Cognitive Assessment Protocol (HCAP) Study during the HRS 2016 field period, in which we administered a supplemental in-home 1-hour battery of cognitive tests to about 3,200 randomly selected and nationally representative HRS respondents aged 65+, as well as a 20-minute informant interview. In the proposed HCAP 2020 follow-up study, we will re-administer the same HCAP in-home cognitive assessment and informant report to all surviving members of the original HCAP sample (n ~ 2,250), and to a new random sample of those aged 65 to 68 in 2020 (n ~ 720). The HCAP 2020 follow-up study will provide extensive new data to better assess trajectories of cognitive decline among older US adults, including the incidence of new cognitive impairment and dementia. These data will also provide an unprecedented opportunity to better understand trends in the incidence and prevalence of dementia in the US and around the world.

项目总结/摘要 健康与退休研究（HRS）合作协议的主要目的是收集和 分发多学科数据以支持老龄化研究。认知障碍和痴呆症，包括 阿尔茨海默氏病和阿尔茨海默氏病相关痴呆（AD/ADRD）给老年人带来了巨大的负担。 家庭和政府政策。为研究界提供新的和更丰富的数据， 认知障碍和痴呆的患病率、预测因素和结局，我们进行了HRS HRS 2016现场期间的协调认知评估方案（HCAP）研究，其中我们 对大约3,200名随机选择的人进行了一系列补充的1小时家庭认知测试， 65岁以上具有全国代表性的HRS受访者，以及20分钟的知情人访谈。在 在拟议的HCAP 2020随访研究中，我们将重新进行相同的HCAP家庭认知评估 和告密者报告的所有幸存成员的原始HCAP样本（n ~ 2，250），并以一个新的随机 2020年65至68岁人群样本（n ~ 720）。HCAP 2020后续研究将提供广泛的新信息， 数据，以更好地评估美国老年人认知能力下降的轨迹，包括新的 认知障碍和痴呆。这些数据也将提供一个前所未有的机会， 了解美国和世界各地痴呆症发病率和患病率的趋势。