Administrative Core (Core A)

行政核心(核心A)

基本信息

  • 批准号:
    10405114
  • 负责人:
  • 金额:
    $ 23.79万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2018
  • 资助国家:
    美国
  • 起止时间:
    2018-09-15 至 2025-05-31
  • 项目状态:
    未结题

项目摘要

ABSTRACT Given the success, efficiency, and integration achieved in our first cycle, we will retain the previous structure of our Administrative Core (Core A), which will provide the essential administrative management and scientific leadership to facilitate and ensure productivity and integration of effort between all 5 proposed projects and 2 additional cores for the proposed Program Project renewal. We propose the following aims: (1) to provide overall leadership and organization that will ensure regular, ongoing, coordinated scientific interaction, planning, learning and feedback between all cores and projects, and effective and efficient use of shared resources; (2) to monitor timely progress and effectiveness of operations of all cores and projects, jointly holding investigators accountable for products expected on those timelines, and requiring any course corrections, as needed; (3) to convene meetings with the Safety Officer on a quarterly basis, and coordinate preparation of all necessary safety monitoring materials across all projects and cores; and (4) to conduct all reporting activities required by the National Institute on Aging, our Scientific Advisory Board, our safety monitoring process, and institutional review boards. The organizational structure of the Core will include a central Executive Committee, the main decision-making and policy group; Operations Committee, in charge of day-to-day operations; Scientific Working Group, for scientific advancement and productivity in abstracts and papers; Publications Committee, providing oversight and approval of publication requests; Biorepository/Database Committee, providing oversight and approval of requests for data sharing and use of Biorepository specimens; Fiscal Management Committee, tracking all budgets and subcontracts to maintain fiscal accountability; and the Scientific Advisory Board, meeting annually to evaluate and guide the progress of the Program Project. The Core has already demonstrated its success in managing a complex program across multiple sites and holding the leaders accountable for timelines and productivity. The Core established the central infrastructure and successfully enrolled a large and complex cohort of over 560 surgical patients, with high quality data. Demonstrated productivity has included 3 Advisory Board meetings, 5 Annual Scientific Symposia, 73 published manuscripts, an additional 2 publications under review, >90 conference presentations, and >9 related grants and supplements. By bringing investigators together for regular meetings and scientific symposia, and leveraging resources across projects, Core A will be able to ensure productive interactions between investigators, explore cross-linking hypotheses between projects, and create a whole that is greater than the sum of its parts. Importantly, our streamlined approach with efficient centralized enrollment and collection of the primary data and sharing of Core resources, augmented with specialized data from individual projects, permits our expansion to 5 projects. This successful Core with established infrastructure and procedures provides a strong foundation to ensure the success of the Delirium Program Project renewal.
抽象的 鉴于我们在第一个周期中取得的成功、效率和整合,我们将保留之前的结构 我们的行政核心(核心A),它将提供必要的行政管理和科学 领导力促进和确保所有 5 个拟议项目和 2 个项目之间的生产力和工作整合 用于拟议计划项目更新的额外核心。我们提出以下目标: (1) 提供 总体领导和组织将确保定期、持续、协调的科学互动, 所有核心和项目之间的规划、学习和反馈,以及有效和高效地利用共享资源 资源; (2) 共同监控所有核心和项目运营的及时进展和有效性 让调查人员对这些时间表上预期的产品负责,并要求采取任何措施 根据需要进行更正; (三)每季度召开安全主任会议,协调工作 准备所有项目和核心的所有必要的安全监测材料; (4) 进行所有 国家老龄化研究所、我们的科学顾问委员会、我们的安全要求的报告活动 监督流程和机构审查委员会。核心的组织结构将包括 中央执行委员会,主要决策和政策小组;运营委员会,负责 日常运营;科学工作组,促进科学进步和摘要生产力 和论文;出版委员会,负责监督和批准出版请求; 生物样本库/数据库委员会,负责监督和批准数据共享和使用的请求 生物样本库标本;财政管理委员会,跟踪所有预算和分包合同以维持 财政责任;和科学顾问委员会每年举行会议以评估和指导进展 计划项目的。 Core 已经证明了其在管理复杂项目方面的成功 跨多个站点并让领导者对时间表和生产力负责。核心成立 中央基础设施并成功招募了超过 560 名手术患者的庞大而复杂的队列, 具有高质量的数据。所展示的生产力包括 3 次顾问委员会会议、5 次年度科学会议 研讨会、73 篇已发表的手稿、另外 2 篇出版物正在审查中、> 90 次会议演讲、 >9 项相关补助金和补助金。通过将研究人员聚集在一起进行定期会议和科学 研讨会并利用跨项目的资源,核心 A 将能够确保富有成效的互动 研究人员之间的合作,探索项目之间的交叉链接假设,并创建一个更大的整体 比其各部分的总和。重要的是,我们通过高效的集中注册和简化的方法 收集原始数据并共享核心资源,并通过个人的专业数据进行增强 项目,允许我们扩展到 5 个项目。这个成功的核心拥有成熟的基础设施和 程序为确保谵妄计划项目更新的成功提供了坚实的基础。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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SHARON K. INOUYE其他文献

SHARON K. INOUYE的其他文献

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{{ truncateString('SHARON K. INOUYE', 18)}}的其他基金

NIDUS II: Advanced-Stage Development and Utilization of the NIDUS Research Infrastructure to Advance Interdisciplinary Aging Research in Delirium
NIDUS II:NIDUS 研究基础设施的高级开发和利用,以推进谵妄的跨学科衰老研究
  • 批准号:
    10187721
  • 财政年份:
    2021
  • 资助金额:
    $ 23.79万
  • 项目类别:
NIDUS II: Advanced-Stage Development and Utilization of the NIDUS Research Infrastructure to Advance Interdisciplinary Aging Research in Delirium
NIDUS II:NIDUS 研究基础设施的高级开发和利用,以推进谵妄的跨学科衰老研究
  • 批准号:
    10561669
  • 财政年份:
    2021
  • 资助金额:
    $ 23.79万
  • 项目类别:
Amyloid PET and blood biomarker supplement to the Delirium Program Project
淀粉样蛋白 PET 和血液生物标志物对谵妄计划项目的补充
  • 批准号:
    10430721
  • 财政年份:
    2021
  • 资助金额:
    $ 23.79万
  • 项目类别:
NIDUS II: Advanced-Stage Development and Utilization of the NIDUS Research Infrastructure to Advance Interdisciplinary Aging Research in Delirium
NIDUS II:NIDUS 研究基础设施的高级开发和利用,以推进谵妄的跨学科衰老研究
  • 批准号:
    10407605
  • 财政年份:
    2021
  • 资助金额:
    $ 23.79万
  • 项目类别:
Delirium, Dementia, and the Vulnerable Brain: An Integrative Approach
谵妄、痴呆和脆弱的大脑:综合方法
  • 批准号:
    10405113
  • 财政年份:
    2018
  • 资助金额:
    $ 23.79万
  • 项目类别:
Social Isolation and Loneliness due to COVID-19: Effect on Cognitive, Physical, and Mental Health in Older Adults in the SAGES Study
COVID-19 造成的社会孤立和孤独感:SAGES 研究中对老年人认知、身体和心理健康的影响
  • 批准号:
    10199108
  • 财政年份:
    2018
  • 资助金额:
    $ 23.79万
  • 项目类别:
Delirium, Dementia, and the Vulnerable Brain: An Integrative Approach
谵妄、痴呆和脆弱的大脑:综合方法
  • 批准号:
    10646679
  • 财政年份:
    2018
  • 资助金额:
    $ 23.79万
  • 项目类别:
Delirium, Alzheimer's Disease Biomarkers, and Long-Term Cognitive Decline
谵妄、阿尔茨海默病生物标志物和长期认知能力下降
  • 批准号:
    10405117
  • 财政年份:
    2018
  • 资助金额:
    $ 23.79万
  • 项目类别:
Development and Testing of a Framework of Social Determinants of Health for Delirium Tailored to Older Adults
开发和测试针对老年人的谵妄健康社会决定因素框架
  • 批准号:
    10362053
  • 财政年份:
    2018
  • 资助金额:
    $ 23.79万
  • 项目类别:
Development and Validation of a Delirium Severity Toolkit
谵妄严重程度工具包的开发和验证
  • 批准号:
    9520730
  • 财政年份:
    2017
  • 资助金额:
    $ 23.79万
  • 项目类别:

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