Administrative Core (Core A)
行政核心(核心A)
基本信息
- 批准号:10405114
- 负责人:
- 金额:$ 23.79万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-09-15 至 2025-05-31
- 项目状态:未结题
- 来源:
- 关键词:AccountabilityAdministrative CoordinationAgingBiological Specimen databaseBrainBudgetsChargeCollectionCommunicationComplexDataData CollectionDecision MakingDeliriumDementiaEffectivenessEnrollmentEnsureFeedbackFoundationsFundingGoalsGrantHuman ResourcesIndividualInfrastructureInstitutesInstitutional Review BoardsLeadershipLearningLinkManuscriptsMissionMonitorNational Institute on AgingOffice of Administrative ManagementOperative Surgical ProceduresPaperPatientsPoliciesPolicy DevelopmentsPreparationPrincipal InvestigatorProbability SamplesProceduresProcessProductivityProtocols documentationPublicationsPublishingRehabilitation CentersReportingResearchResearch PersonnelResource SharingResourcesRoleSafetySiteSourceSpecimenStatistical Data InterpretationStructureSumTimeTimeLineUpdateWritingbasebiobankcohortcrosslinkdata managementdata sharingdesignexperienceflexibilitymeetingsoperationorganizational structureprogramssuccesssymposiumworking group
项目摘要
ABSTRACT
Given the success, efficiency, and integration achieved in our first cycle, we will retain the previous structure of
our Administrative Core (Core A), which will provide the essential administrative management and scientific
leadership to facilitate and ensure productivity and integration of effort between all 5 proposed projects and 2
additional cores for the proposed Program Project renewal. We propose the following aims: (1) to provide
overall leadership and organization that will ensure regular, ongoing, coordinated scientific interaction,
planning, learning and feedback between all cores and projects, and effective and efficient use of shared
resources; (2) to monitor timely progress and effectiveness of operations of all cores and projects, jointly
holding investigators accountable for products expected on those timelines, and requiring any course
corrections, as needed; (3) to convene meetings with the Safety Officer on a quarterly basis, and coordinate
preparation of all necessary safety monitoring materials across all projects and cores; and (4) to conduct all
reporting activities required by the National Institute on Aging, our Scientific Advisory Board, our safety
monitoring process, and institutional review boards. The organizational structure of the Core will include a
central Executive Committee, the main decision-making and policy group; Operations Committee, in charge
of day-to-day operations; Scientific Working Group, for scientific advancement and productivity in abstracts
and papers; Publications Committee, providing oversight and approval of publication requests;
Biorepository/Database Committee, providing oversight and approval of requests for data sharing and use of
Biorepository specimens; Fiscal Management Committee, tracking all budgets and subcontracts to maintain
fiscal accountability; and the Scientific Advisory Board, meeting annually to evaluate and guide the progress
of the Program Project. The Core has already demonstrated its success in managing a complex program
across multiple sites and holding the leaders accountable for timelines and productivity. The Core established
the central infrastructure and successfully enrolled a large and complex cohort of over 560 surgical patients,
with high quality data. Demonstrated productivity has included 3 Advisory Board meetings, 5 Annual Scientific
Symposia, 73 published manuscripts, an additional 2 publications under review, >90 conference presentations,
and >9 related grants and supplements. By bringing investigators together for regular meetings and scientific
symposia, and leveraging resources across projects, Core A will be able to ensure productive interactions
between investigators, explore cross-linking hypotheses between projects, and create a whole that is greater
than the sum of its parts. Importantly, our streamlined approach with efficient centralized enrollment and
collection of the primary data and sharing of Core resources, augmented with specialized data from individual
projects, permits our expansion to 5 projects. This successful Core with established infrastructure and
procedures provides a strong foundation to ensure the success of the Delirium Program Project renewal.
摘要
鉴于我们在第一个周期中取得的成功、效率和集成,我们将保留以前的结构
我们的行政核心(核心A),这将提供必要的行政管理和科学
发挥领导作用,促进和确保所有5个拟议项目和2个项目之间的工作效率和工作整合
建议的计划项目续订的额外核心。我们建议的目标如下:(1)提供
确保定期、持续、协调的科学互动的全面领导和组织,
所有核心和项目之间的规划、学习和反馈,以及有效和高效地使用共享
资源;(2)联合监测所有核心和项目的及时进展和业务成效
让调查人员对这些时间表上预期的产品负责,并要求任何课程
根据需要进行纠正;(3)每季度与安全干事召开会议,并协调
准备所有项目和核心的所有必要的安全监测材料;以及(4)进行所有
国家老龄研究所、我们的科学咨询委员会、我们的安全所要求的报告活动
监测进程和机构审查委员会。核心的组织结构将包括一个
中央执行委员会,主要决策和政策小组;业务委员会,负责
科学工作组,以促进科学进步和摘要的生产力
和论文;出版物委员会,负责监督和批准出版请求;
生物储存库/数据库委员会,监督和批准数据共享和使用的请求
生物库标本;财政管理委员会,跟踪所有预算和分包合同以维护
财政问责;以及科学咨询委员会,每年举行会议,评估和指导进展情况
该计划项目的。核心已经证明了它在管理复杂项目方面的成功
跨多个站点,并让领导者对时间表和工作效率负责。核心已经确立
中心基础设施,并成功招募了超过560名手术患者的庞大而复杂的队列,
拥有高质量的数据。展示的工作效率包括3次咨询委员会会议、5次年度科学
研讨会,73份已发表的手稿,另外2份正在审查的出版物,以及90个会议报告,
和>;9相关助学金和补助金。通过将调查人员聚集在一起定期开会和科学研究
研讨会,并利用跨项目的资源,核心A将能够确保富有成效的互动
在研究人员之间,探索项目之间的交叉链接假设,并创建一个更大的整体
而不是它各部分的总和。重要的是,我们简化了高效集中注册的方法,
收集主要数据和共享核心资源,并使用来自个人的专门数据进行扩充
项目,允许我们扩展到5个项目。这一成功的核心具备成熟的基础设施和
程序为确保Delirium计划项目续签的成功提供了坚实的基础。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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SHARON K. INOUYE其他文献
SHARON K. INOUYE的其他文献
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{{ truncateString('SHARON K. INOUYE', 18)}}的其他基金
NIDUS II: Advanced-Stage Development and Utilization of the NIDUS Research Infrastructure to Advance Interdisciplinary Aging Research in Delirium
NIDUS II:NIDUS 研究基础设施的高级开发和利用,以推进谵妄的跨学科衰老研究
- 批准号:
10187721 - 财政年份:2021
- 资助金额:
$ 23.79万 - 项目类别:
NIDUS II: Advanced-Stage Development and Utilization of the NIDUS Research Infrastructure to Advance Interdisciplinary Aging Research in Delirium
NIDUS II:NIDUS 研究基础设施的高级开发和利用,以推进谵妄的跨学科衰老研究
- 批准号:
10561669 - 财政年份:2021
- 资助金额:
$ 23.79万 - 项目类别:
Amyloid PET and blood biomarker supplement to the Delirium Program Project
淀粉样蛋白 PET 和血液生物标志物对谵妄计划项目的补充
- 批准号:
10430721 - 财政年份:2021
- 资助金额:
$ 23.79万 - 项目类别:
NIDUS II: Advanced-Stage Development and Utilization of the NIDUS Research Infrastructure to Advance Interdisciplinary Aging Research in Delirium
NIDUS II:NIDUS 研究基础设施的高级开发和利用,以推进谵妄的跨学科衰老研究
- 批准号:
10407605 - 财政年份:2021
- 资助金额:
$ 23.79万 - 项目类别:
Delirium, Dementia, and the Vulnerable Brain: An Integrative Approach
谵妄、痴呆和脆弱的大脑:综合方法
- 批准号:
10405113 - 财政年份:2018
- 资助金额:
$ 23.79万 - 项目类别:
Social Isolation and Loneliness due to COVID-19: Effect on Cognitive, Physical, and Mental Health in Older Adults in the SAGES Study
COVID-19 造成的社会孤立和孤独感:SAGES 研究中对老年人认知、身体和心理健康的影响
- 批准号:
10199108 - 财政年份:2018
- 资助金额:
$ 23.79万 - 项目类别:
Delirium, Dementia, and the Vulnerable Brain: An Integrative Approach
谵妄、痴呆和脆弱的大脑:综合方法
- 批准号:
10646679 - 财政年份:2018
- 资助金额:
$ 23.79万 - 项目类别:
Delirium, Alzheimer's Disease Biomarkers, and Long-Term Cognitive Decline
谵妄、阿尔茨海默病生物标志物和长期认知能力下降
- 批准号:
10405117 - 财政年份:2018
- 资助金额:
$ 23.79万 - 项目类别:
Development and Testing of a Framework of Social Determinants of Health for Delirium Tailored to Older Adults
开发和测试针对老年人的谵妄健康社会决定因素框架
- 批准号:
10362053 - 财政年份:2018
- 资助金额:
$ 23.79万 - 项目类别:
Development and Validation of a Delirium Severity Toolkit
谵妄严重程度工具包的开发和验证
- 批准号:
9520730 - 财政年份:2017
- 资助金额:
$ 23.79万 - 项目类别:
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