Scientific Working Group

项目总结 科学工作组：创新和实施对结束 艾滋病毒流行(EHE SWG) 芝加哥在遏制艾滋病毒流行方面取得了一些进展。然而，更有效的预防、诊断、 治疗和公共卫生对策都需要加速改善艾滋病毒的连续体 有助于实现结束艾滋病毒流行的目标的预防和护理：美国计划(EHE)倡议。 2017年大多数新的艾滋病毒诊断病例在20-29岁年龄组(38%)，并在黑人/非洲人中 美国人(55%)和男男性接触者(63%)居民(芝加哥公共卫生部。HIV/STI监测报告 2017年。2018年12月)。一项研究发现，芝加哥只有43%的非西班牙裔黑人/非裔美国人MSM 在PrEP护理中维持12个月。所有人获得抗逆转录病毒治疗(ART)的机会/成功的限制 种族/族裔加剧了艾滋病毒预防面临的这些挑战。所有艾滋病毒携带者中不到一半的人 2017年，芝加哥公共卫生署(PLWH)实现了病毒抑制(艾滋病毒/性传播感染监测报告2017)。创新之路 和执行终止艾滋病毒流行影响科学工作组(EHE SWG) 最大限度地在芝加哥取得进展以实现EHE目标的广泛目标：减少库克新的艾滋病毒感染 到2030年，该县人口将减少90%。它将催化和开发新的协作和创新建议，以填补 确定差距的优先顺序并解决新出现的机会。EHE SWG充分利用了我们强大的学术专业知识， 并吸引各种有能力的社区合作伙伴，以高效地了解如何推进新的 战略和传播成功。除了强调与以社区为基础的地方伙伴关系外 服务提供商已经与第三海岸艾滋病研究中心(TC CFAR)进行了富有成效的合作 EHE SWG将与整个芝加哥的社区组织和服务提供商建立新的合作伙伴关系。 EHE特别工作组还将从实施EHE行政补编中吸取和调整经验教训 到全国各地的CFAR和ARC(作为TC CFAR领导的实施科学协调， 咨询和协作倡议(ISC3I)在所有EHE获奖者、NIH和 卫生和公众服务部)。EHE特别工作组的具体目标是：(1)确保有效传播有关资金的信息 来自不断发展的卫生部EHE倡议的服务交付/评估和实施研究的机会 当它们出现并吸引任何和所有感兴趣的芝加哥合作伙伴参与解决EHE目标的合作时； (2)组建、支持和定期更新开展专题研究实践的“行动小组” 与EHE目标和当地公共卫生优先事项保持一致的伙伴关系；(3)以提案为重点的“预先定位” 研究-实践伙伴关系行动团队提交具有响应性和竞争力的建议，以实现变革 他们在TC CFAR实施科学专家和其他相关TC CFAR的投入下开发创新 资源，一旦国家卫生研究院发布了以EHE为重点的资金机会(通过年度CFAR 行政补充RFA)、疾病预防控制中心或人权事务高级专员办事处。

PROJECT SUMMARY SCIENTIFIC WORKING GROUP: INNOVATION AND IMPLEMENTATION FOR IMPACT ON ENDING THE HIV EPIDEMIC (EHE SWG) Chicago has made some progress in curbing the HIV epidemic. However, more effective prevention, diagnosis, treatment, and public health responses are each needed to accelerate improvements to the continuums of HIV prevention and care that will help meet goals of the Ending the HIV Epidemic: A Plan for America (EHE) initiative. Most new HIV diagnoses in 2017 were within the 20-29 year age group (38%), and among black/African Americans (55%) and MSM (63%) residents (Chicago Department of Public Health. HIV/STI Surveillance Report 2017. December 2018). One study found that only 43% of non-Hispanic black/African American MSM in Chicago were maintained in PrEP care at 12 months. Limits in antiretroviral treatment (ART) access/success across all race/ethnicities compound these challenges to HIV prevention. Fewer than half of all persons living with HIV (PLWH) in Chicago achieved viral suppression in 2017 (HIV/STI Surveillance Report 2017). The Innovation and Implementation for Impact on Ending the HIV Epidemic Scientific Working Group (EHE SWG) has the broad objective of maximizing progress in Chicago toward a goal of EHE: reduce new HIV infections in Cook County by 90% in 2030. It will catalyze and develop new collaborations and innovative proposals that fill prioritized gaps and address emerging opportunities. The EHE SWG fully utilizes our strong academic expertise, and engages diverse and able community partners, to efficiently learn how to advance implementation of new strategies and spread the successes. In addition to emphasizing local partnerships with community-based service providers already working productively with the Third Coast Center for AIDS Research (TC CFAR), the EHE SWG will start new partnerships with community organizations and service providers across Chicagoland. The EHE SWG will also learn and adapt lessons from the implementation of EHE administrative supplements to CFARs and ARCs around the country (as the TC CFAR-led Implementation Science Coordination, Consultation, and Collaboration Initiative (ISC3I) shares information across all EHE awardees, the NIH, and DHHS). The specific aims of the EHE SWG are: (1) to ensure efficient dissemination of information about funding opportunities for service delivery/evaluation and implementation research from the evolving DHHS EHE initiative as they emerge and engage any and all interested Chicagoland partners in collaborations addressing EHE goals; (2) to form, support, and regularly refresh “action teams” developing topic-focused research-practice partnerships aligned with EHE goals and local public health priorities; (3) to ‘pre-position’ proposal-focused research-practice partnership action teams to submit responsive and competitive proposals for transformative innovations they develop with input from TC CFAR implementation science experts and other relevant TC CFAR resources, as soon as EHE-focused funding opportunities are issued from the NIH (via annual CFAR Administrative Supplement RFAs), CDC, or HRSA.