Unobtrusive Monitoring of Affective Symptoms and Cognition using Keyboard Dynamics

使用键盘动力学对情感症状和认知进行不引人注目的监测

• 批准号: 10406131
• 负责人: Olusola A. Ajilore
• 金额: $ 22.93万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-03-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10406131
• 关键词: 18 year old; Accelerometer; Administrative Supplement; Adolescent; Affective Symptoms; Apple; Behavior; Biological Markers; Biomedical Research; Bipolar Disorder; Brain; Cellular Phone; Clinical; Cognition; Cognitive; Collaborations; Collection; Computer software; Consent; Consultations; Custom; Data; Data Engineering; Data Science; Devices; Disease; Dysthymic Disorder; Emotions; Ensure; Environment; FAIR principles; Feasibility Studies; Female; Financial cost; Foundations; Funding; Future; Future Generations; Goals; Grant; Health; Health Care Costs; Impaired cognition; Impairment; Individual; Infrastructure; Link; Maintenance; Mental Depression; Mental Health; Metadata; Modernization; Monitor; Mood Disorders; Motor; Multiple Sclerosis; Operating System; Parents; Participant; Patients; Periodicity; Persons; Phenotype; Population; Postdoctoral Fellow; Property; Regulation; Research; Research Personnel; Sampling; Secure; Severities; Sleep; Strategic Planning; Sum; Technology; Time; U-Series Cooperative Agreements; Unipolar Depression; United States; United States National Institutes of Health; Update; base; brain health; circadian; clinically relevant; cognitive function; cost effective; dashboard; data analysis pipeline; data ecosystem; data standards; digital; fitness; improved; innovation; interest; interoperability; kinematics; mood symptom; neurobehavioral; neurosteroids; novel; open data; parent project; personalized medicine; precision medicine; prospective; smartphone Application; smartphone based assessment; software development; software infrastructure; suicidal risk; treatment response; virtual

The goal of the parent project “Unobtrusive Monitoring of Affective Symptoms and Cognition using Keyboard Dynamics (UnMASCK)” is to develop digital biomarkers derived from smartphone typing dynamics and motor kinematics which can be used to predict alterations in brain network properties associated with cognitive dysfunction and prospective changes in clinical mood symptoms. The digital data is unobtrusively collected via a novel platform “BiAffect” in a transdiagnostic sample of subjects with mood disorders and health controls. The BiAffect platform collects metadata related to typing behaviors such as keypress types, timestamps, and accelerometry and uploads these data to the study server. Subject specific summary metrics are calculated locally and presented to the user via a dashboard. With this supplement our goal is to update the software infrastructure of the BiAffect platform in order to facilitate interoperability, collaboration with other researchers, and integration with the smartphone hardware and operating system upgrades. To achieve these goals, we plan to refactor the BiAffect codebase to enable more robust multi-developer collaboration and version control. We also plan to create standardized data processing pipelines to support collaborations with researchers who may have varying levels of capacity for data science and engineering.

母项目“情感症状和认知的非侵入性监测”的目标 使用键盘动力学（UnMASCK）”是开发数字生物标志物， 智能手机打字动力学和电机运动学，可用于预测 与认知功能障碍相关的脑网络特性以及 临床情绪症状数字数据是通过一个新颖的平台不引人注目地收集的 “BiAffect”在患有情绪障碍和健康对照的受试者的跨诊断样本中。的 BiAffect平台收集与键入行为相关的元数据，例如按键类型， 时间戳和加速度测量，并将这些数据上传到研究服务器。受试者特定 摘要度量在本地计算并经由仪表板呈现给用户。 通过此补充，我们的目标是更新BiAffect平台的软件基础设施， 为了促进互操作性，与其他研究人员的合作，以及与 智能手机硬件和操作系统升级。为了实现这些目标，我们计划 重构BiAffect代码库，以实现更强大的多开发人员协作和版本 控制我们还计划创建标准化的数据处理管道来支持协作 与可能具有不同数据科学和工程能力水平的研究人员一起。