(2/2) TUFCCC/HC Regional Comprehensive Cancer Health Disparity Partnership

(2/2) TUFCCC/HC 区域综合癌症健康差异伙伴关系

• 批准号: 10411441
• 负责人: Joel Erblich
• 金额: $ 13.04万
• 依托单位: HUNTER COLLEGE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-18 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10411441
• 关键词: Advanced Malignant Neoplasm; African; African American; Area; Asian Pacific American; Asians; Behavioral; Bioinformatics; Biomedical Research; Biometry; Cancer Burden; Cancer Center; Cancer Control; Clinical; Collaborations; Colorectal Cancer; Communities; Community Networks; Community Outreach; Core Facility; Development; Doctor of Philosophy; Early Diagnosis; Early treatment; Education; Evaluation; Faculty; Fox Chase Cancer Center; Funding; Goals; Hispanic Americans; Human Resources; Incidence; Infrastructure; Institution; Joints; Leadership; Malignant Neoplasms; Malignant neoplasm of liver; Malignant neoplasm of lung; Malignant neoplasm of prostate; Mentors; Minority; Minority Groups; New Jersey; New York City; Not Hispanic or Latino; Outreach Research; Peer Review; Pennsylvania; Phase; Pilot Projects; Population; Positioning Attribute; Prevalence; Program Development; Publications; Recording of previous events; Regional Cancer; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Scientist; Series; Special Population; Students; Training Programs; Underrepresented Minority; Underrepresented Students; Underserved Population; Universities; anticancer research; cancer health disparity; cancer prevention; cancer therapy; cancer type; career; career development; cohesion; college; community based participatory research; education planning; education research; experience; faculty mentor; graduate student; health disparity; health equity; innovation; interest; malignant breast neoplasm; member; mortality; multidisciplinary; organizational structure; programs; racial and ethnic; racial and ethnic disparities; recruit; translational scientist; treatment research; undergraduate student; underrepresented minority student; underserved minority

PROJECT SUMMARY Overall TUFCCC: Grace X. Ma, PhD (Contact PI) and Jean-Pierre Issa, MD (MPI) HC: Olorunseun O. Ogunwobi, MD, PhD (Contact PI) and Joel Erblich, PhD, MPH (MPI) Despite advances in early detection and treatment of cancer, significant racial/ethnic disparities exist in African, Asian-Pacific, and Hispanic Americans, bearing disproportionate cancer burden. These cancer health disparities are particularly salient in the Pennsylvania-New Jersey-New York City (PNN) region, where there is a high concentration of minority populations compared to elsewhere in the U.S. Moreover, despite numerous academic institutions conducting biomedical research in PNN region, there is a critical dearth of underrepresented minorities (URMs) involved in cancer research, who bring unique scientific and cultural strengths necessary to conquer cancer health disparities. Building on collaborative history, successful and synergistic planning activities/accomplishments between TUFCCC and HC, and NCI-funded cancer disparities research networks (CNPC), we propose to establish TUFCCC/HC Regional Comprehensive Cancer Health Disparities Partnership to reduce cancer health disparities in PNN region. The goals of this Partnership are to: a) develop a strong and sustainable collaborative cancer health equity research infrastructure, b) support the development of outstanding URM students and ESIs who are committed to careers in cancer research, and c) collaboratively engage the community in enhancing quality and feasibility of these efforts. These goals will be achieved through the following specific aims: Aim 1. Create and enhance sustainable cancer disparity research collaborations in URM populations between TUFCCC and HC. Aim 1a. Enhance institutional cancer research capacity at HC in basic, behavioral and clinical cancer research and provide HC researchers with access to cancer core facilities, resources and expertise at TUFCCC. Aim 1b. Increase the number of research projects at TUFCCC that focus on cancer health disparities in underserved populations throughout the PNN region. Aim 2. Provide research education opportunities in cancer disparities to support a pipeline of diverse and URM undergraduate and graduate students at HC and TUFCCC. Aim 3. Establish a sustainable career development program to increase the number and diversity of investigators/ESIs to conduct cancer and cancer disparity research at both HC and TUFCCC. Aim 4. Use a Community-Based Participatory Research approach to engage researchers, students and community leaders to develop and implement culturally appropriate collaborative cancer outreach, research and education initiatives to increase access to, and utilization of cancer prevention, early detection and treatment in underserved disparity populations. To achieve U54 goals/aims, the Partnership includes two innovative and rigorous full research projects, a pilot project and a series of integrated cores, including Research Education, Planning and Evaluation, Community Outreach, and Biostatistics/Bioinformatics. Administrative Core will provide oversight and cohesion to the Partnership. Finally, the Partnership has a high level of institutional commitments from both TUFCCC and HC and is well positioned to make significant contributions to advancing cancer health equity in PNN region and beyond.

项目摘要 整体 格蕾丝·X Ma，PhD（联系PI）和Jean-Pierre Issa，MD（MPI） HC：Olorunseun O. Ogunwobi，MD，PhD（联系PI）和Joel Erblich，PhD，MPH（MPI） 尽管在癌症的早期发现和治疗方面取得了进展，但在非洲， 亚太裔和西班牙裔美国人承担着不成比例的癌症负担。这些癌症健康 在宾夕法尼亚州-新泽西州-约克市（PNN）地区， 与美国其他地方相比，少数民族人口高度集中。 在PNN地区进行生物医学研究的学术机构， 参与癌症研究的代表性不足的少数民族（URM），他们带来了独特的科学和文化 克服癌症健康差距所需的力量。在合作历史的基础上， TUFCCC和HC之间的协同规划活动/成就，以及NCI资助的癌症差异 研究网络（CNPC），我们建议建立TUFCCC/HC区域综合癌症健康 差异伙伴关系，以减少PNN地区的癌症健康差异。该伙伴关系的目标是： a）发展强大和可持续的癌症健康公平合作研究基础设施，B）支持 发展杰出的URM学生和致力于癌症研究事业的ESI，以及c） 与社区协作，提高这些工作的质量和可行性。这些目标将是 通过以下具体目标实现：目标1。创造和加强可持续的癌症差距 TUFCCC和HC之间在URM人群中的研究合作。目标1a。增强制度毒瘤 研究能力在HC在基础，行为和临床癌症研究，并提供HC研究人员， 获得TUFCCC的癌症核心设施，资源和专业知识。目标1b。使更多的 TUFCCC的研究项目，重点关注癌症健康的差距，在整个服务不足的人群 PNN地区。目标二。提供癌症差异的研究教育机会，以支持 HC和TUFCCC的多样化和URM本科生和研究生。目标3。建立可持续 职业发展计划，以增加研究者/ESI的数量和多样性， 癌症差异研究在HC和TUFCCC。目标4。使用基于社区的前瞻性研究 让研究人员、学生和社区领导人参与制定和实施文化 采取适当的癌症合作外展、研究和教育举措， 利用癌症预防，早期发现和治疗服务不足的差距人口。实现 U 54目标/宗旨，该伙伴关系包括两个创新和严格的全面研究项目，一个试点项目， 一系列综合核心，包括研究教育，规划和评估，社区外展， 生物统计学/生物信息学行政核心将为伙伴关系提供监督和凝聚力。 最后，该伙伴关系得到了图瓦卢气候变化框架公约和高级专员的高度机构承诺， 定位为促进PNN地区及其他地区的癌症健康公平做出重大贡献。