Improving the usage and impact of the Integrated Aging Studies Databank and Registry

改善综合老龄化研究数据库和登记处的使用和影响

• 批准号: 10408207
• 负责人: DALANE W KITZMAN
• 金额: $ 23.23万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-15 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10408207
• 关键词: Address; Adopted; Aging; American; Applications Grants; Area; Biological Specimen Banks; Capsicum; Certification; Characteristics; Collaborations; Communities; Data; Data Set; Development; Elderly; FAIR principles; Fostering; Frequencies; Funding; Future; Generations; Geography; Gerontology; Goals; Hand; Infrastructure; Journals; Licensing; Link; Measures; Medical; Metadata; Modernization; Paper; Physical Function; Pilot Projects; Play; Postdoctoral Fellow; Process; Publications; Publishing; Quality Control; Registries; Research; Research Personnel; Resource Sharing; Resources; Role; Sample Size; Sampling; Science; Scientist; Statistical Methods; Structure; TRUST principles; Testing; Text; Trust; United States National Institutes of Health; Update; Visual; career; computer center; cost; data access; data repository; data sharing; design; early-career faculty; experience; forest; improved; innovation; interest; interoperability; machine learning method; multiple datasets; repository; statistics; study characteristics; synergism; tool; usability

Project Summary The Integrated Aging Studies Databank and Registry (IASDR) is a repository designed for sharing data across the NIH-funded national network of Older Americans Independence Centers (OAICs). The IASDR hosted and maintained by the OAIC’s Coordinating Center (CC). As a domain-specific repository, the existing IASDR contains multiple data sets generated from aging studies conducted at the Wake Forest OAIC (WF-OAIC), as well as a biospecimen bank for samples collected from some of the included studies. The IASDR thus serves as a valuable resource for the aging research community, especially for early career faculty. The data repository befits early career investigators who want to conduct small pilot studies for testing out conjectures and research hypotheses, and to efficiently produce useful information such as preliminary effect sizes for grant applications or to power future studies. Gaps were identified when the IASDR was evaluated against modern repository requirements. The IASDR was first started more than a decade ago, and the development process did not necessarily strictly adhere to contemporary biomedical-data repository principles such as the FAIR and TRUST principles. Importantly, barriers are present for users in accessing key information for decision support. For example, currently summary statistics such as mean, standard deviation, frequency for variables and association information between variables, which are often critical in helping users to decide whether or not to pursue actual data, are not present in the IASDR metadata. The lack of such preliminary information could deter interested users from using the repository. To address gaps and limitations of the IASDR as related to its “FAIR”-ness and “TRUST”- worthiness, this proposal contains two specific aims: (1) Enhance the metadata layer by providing users with key analytic information such as mean, frequency, and association between variables, and (2) improve the IASDR along the FAIR and TRUST principles and seek certification.

项目摘要 综合老龄化研究数据库和登记处（IASDR）是一个专为 在NIH资助的美国老年人独立国家网络中共享数据 中心（OAIC）。IASDR由OAIC的协调中心主持和维护。 作为一个特定于领域的存储库，现有的IASDR包含从 在维克森林OAIC（WF-OAIC）进行的老化研究，以及生物标本库 从一些纳入的研究中收集的样本。因此，IASDR是一个有价值的 老龄化研究社区的资源，特别是对早期职业教师。数据 存储库适合那些希望进行小型试点研究以进行测试的早期职业调查人员 假设和研究假设，并有效地产生有用的信息，如 初步的效应量用于资助申请或为未来的研究提供动力。查明了差距 当IASDR根据现代存储库要求进行评估时。IASDR是第一个 十多年前就开始了，发展过程不一定严格 坚持当代生物医学数据存储原则，如公平和信任 原则重要的是，用户在获取决策所需的关键信息方面存在障碍 支持.例如，目前的汇总统计量，如平均值，标准差，频率 变量和变量之间的关联信息，这些信息通常对帮助 IASDR元数据中不存在用户决定是否追求实际数据的权利。 缺乏这种初步信息可能会阻碍感兴趣的用户使用存储处。 为了解决国际减灾战略在“公平”和“信任”方面的差距和局限性， 值得注意的是，该建议包含两个具体目标：（1）通过以下方式增强元数据层： 为用户提供关键的分析信息，如均值、频率和关联 （2）沿着公平和信任原则改进IASDR， 认证