Development and Testing of MyPEEPS Mobile for Young Transgender Men

项目总结 美国的变性人青年有独特的健康需求，但在获得和 获得有助于不同健康结果的卫生保健服务，包括对艾滋病毒的高度易感性 以及其他性传播感染。新出现的证据已经开始记录与艾滋病毒相关的性风险 在年轻的变性人中(YTM)，以及接触前预防措施的接受率较低 适应症，表明对艾滋病毒感染的易感性很高。尽管患病率很高，风险也增加了 在与顺性男性发生性行为的YTM中，只制定了一项先前的艾滋病毒预防干预措施 解决青年会的具体性健康需求，这表明在艾滋病毒预防科学方面存在严重差距。在……里面 响应这一需求，并在我们强大的前期工作的基础上，我们建议开发一种移动 对MyPEEPS Mobile上YTM建筑的干预，它最初是为非常年轻的性爱开发的 少数族裔男性。这种干预的核心是前提是它将在发展过程中交付给青年 首次性行为之前或同时发生的时期，是干预的重要时刻，在此之前或同时 伴随着高危行为的开始。考虑到艾滋病毒预防科学方面的差距和目前缺乏 有针对性的干预措施，并建立在我们多学科团队在艾滋病毒预防方面的丰富经验基础上， 移动健康、行为干预、随机对照试验和变性人健康，我们建议 以下具体目标：1)使用定性方法、专家反馈和可用性评估，开发 MyPEEPS Mobile for YTM，2)进行试点随机对照试验，以检验其可行性， 修订后的MyPEEPS移动应用程序在80YTM(15-19)样本中的可接受性和初步疗效 几年)，并为未来的疗效试验改进研究方法，以及3)评估诱因、使能和 通过理论指导的深度访谈，加强MyPEEPS Mobile在YTM中的优势因素。这个 针对YTM提出的MyPEEPS干预是一种利用移动技术进行的新颖的循证干预 向高危青年提供艾滋病毒预防信息。这将是第一个开发和试行规模化 UP，由YTM的不同群体设计并试行的移动艾滋病毒预防干预措施。最终产品 这项研究的结果将成为R01应用程序对这一人群进行大规模疗效研究的基础。 针对YTM提出的MyPEEPS移动干预是一种新颖的、以证据为导向的使用移动干预 提供专门为YTM开发的艾滋病毒预防信息的技术。因此，我们是 相信拟议的干预措施将是改善艾滋病毒预防的高影响力干预措施 YTM的行为，并对公众健康的全面改善具有长期影响。

PROJECT SUMMARY Transgender youth in the United States have unique health needs but often face barriers to accessing and receiving health care services which contribute to disparate health outcomes including high vulnerability to HIV and other sexually transmitted infections. Emerging evidence has begun to document HIV-related sexual risk among young transgender men (YTM), as well as low uptake of pre-exposure prophylaxis among those with indications, suggesting high vulnerability to HIV infection. Despite the high prevalence and increased risk of HIV in YTM who have sex with cisgender men, only one prior HIV prevention intervention has been developed to address the specific sexual health needs of YTM, which indicates a critical gap in HIV prevention science. In response to this need, and building off our strong preliminary work, we propose to develop a mobile intervention for YTM building on MyPEEPS Mobile, which was originally developed for very young sexual minority men. Central to this intervention is the premise that it will be delivered to youth during a developmental period that precedes or coincides with sexual debut, an important time for intervention, prior to or concurrent with initiation of high-risk behaviors. Given both the gap in HIV prevention science and the lack of current targeted interventions, and building upon our multidisciplinary team’s extensive experience in HIV prevention, mHealth, behavioral interventions, randomized controlled trials, and transgender health, we propose the following specific aims: 1) Using qualitative methodology, expert feedback, and usability assessments, develop MyPEEPS Mobile for YTM, 2) Conduct a pilot randomized controlled trial to examine the feasibility, acceptability, and preliminary efficacy of the revised MyPEEPS Mobile App in a sample of 80 YTM (15-19 years) and refine the study methods for a future efficacy trial, and 3) Assess predisposing, enabling, and reinforcing factors for MyPEEPS Mobile among YTM through theoretically-guided in-depth interviews. The proposed MyPEEPS intervention for YTM is a novel and evidence-driven intervention using mobile technology to deliver HIV prevention information to high-risk youth. This will be the first study to develop and pilot a scaled- up, mobile HIV prevention intervention designed by, and piloted for, a diverse group of YTM. The final product of this study will be the basis for an R01 application to conduct a large-scale efficacy study for this population. The proposed MyPEEPS Mobile intervention for YTM is a novel and evidence-driven intervention using mobile technology to deliver HIV prevention information specifically developed for YTM. Consequently, we are confident that the proposed intervention will be of high impact intervention for improving HIV prevention behaviors in YTM and have long-term implications for overall improvement in the public’s health.