Development and Testing of MyPEEPS Mobile for Young Transgender Men

项目摘要 美国的跨性别青年有着独特的健康需求，但往往面临着获得和 接受卫生保健服务，导致不同的健康结果，包括艾滋病毒的高度脆弱性 和其他性传播感染。新出现的证据已开始记录与艾滋病毒有关的性风险 在年轻的跨性别男性（YTM）中，以及在那些 这些迹象表明，艾滋病毒感染的脆弱性很高。尽管高患病率和增加的风险， 与顺性别男性发生性关系的YTM中的艾滋病毒，仅制定了一项先前的艾滋病毒预防干预措施 以解决特定的性健康需求的YTM，这表明在艾滋病毒预防科学的关键差距。在 为了满足这一需求，并建立我们强大的初步工作，我们建议开发一个移动的 在MyPEEPS移动的上建立YTM的干预措施，MyPEEPS最初是为非常年轻的性行为开发的 少数民族男子。这种干预的核心是，在发展过程中向青年提供这种干预， 在性初次出现之前或同时的时期，是干预的重要时间，在性初次出现之前或同时 引发高危行为鉴于艾滋病毒预防科学的差距和缺乏现有的 有针对性的干预措施，并建立在我们的多学科团队在艾滋病毒预防方面的丰富经验， 移动健康，行为干预，随机对照试验，和跨性别健康，我们建议 以下具体目标：1）使用定性方法，专家反馈和可用性评估，开发 MyPEEPS移动的用于YTM，2）进行初步随机对照试验以检查可行性， 在80个YTM（15-19）样本中，修订后的MyPEEPS移动的App的可接受性和初步有效性 年），并完善研究方法，为未来的疗效试验，和3）评估易感性，使， 通过理论指导下的深度访谈，在YTM中加强MyPEEPS移动的因素。的 建议的YTM MyPEEPS干预是一种新的、基于证据的干预，使用了移动的技术 向高危青年提供艾滋病毒预防信息。这将是第一个研究开发和试点规模- 由YTM的不同群体设计并试点的向上的移动的艾滋病毒预防干预。最终产品 将作为R 01申请的基础，对该人群进行大规模疗效研究。 所提出的MyPEEPS移动的干预YTM是一种新型的证据驱动的干预，使用移动的 提供专为青训局而设的预防爱滋病资讯的科技。因此，我们 我相信，拟议的干预措施将对改善艾滋病毒预防工作产生重大影响 YTM的行为，并对公众健康的整体改善有长期的影响。

PROJECT SUMMARY Transgender youth in the United States have unique health needs but often face barriers to accessing and receiving health care services which contribute to disparate health outcomes including high vulnerability to HIV and other sexually transmitted infections. Emerging evidence has begun to document HIV-related sexual risk among young transgender men (YTM), as well as low uptake of pre-exposure prophylaxis among those with indications, suggesting high vulnerability to HIV infection. Despite the high prevalence and increased risk of HIV in YTM who have sex with cisgender men, only one prior HIV prevention intervention has been developed to address the specific sexual health needs of YTM, which indicates a critical gap in HIV prevention science. In response to this need, and building off our strong preliminary work, we propose to develop a mobile intervention for YTM building on MyPEEPS Mobile, which was originally developed for very young sexual minority men. Central to this intervention is the premise that it will be delivered to youth during a developmental period that precedes or coincides with sexual debut, an important time for intervention, prior to or concurrent with initiation of high-risk behaviors. Given both the gap in HIV prevention science and the lack of current targeted interventions, and building upon our multidisciplinary team’s extensive experience in HIV prevention, mHealth, behavioral interventions, randomized controlled trials, and transgender health, we propose the following specific aims: 1) Using qualitative methodology, expert feedback, and usability assessments, develop MyPEEPS Mobile for YTM, 2) Conduct a pilot randomized controlled trial to examine the feasibility, acceptability, and preliminary efficacy of the revised MyPEEPS Mobile App in a sample of 80 YTM (15-19 years) and refine the study methods for a future efficacy trial, and 3) Assess predisposing, enabling, and reinforcing factors for MyPEEPS Mobile among YTM through theoretically-guided in-depth interviews. The proposed MyPEEPS intervention for YTM is a novel and evidence-driven intervention using mobile technology to deliver HIV prevention information to high-risk youth. This will be the first study to develop and pilot a scaled- up, mobile HIV prevention intervention designed by, and piloted for, a diverse group of YTM. The final product of this study will be the basis for an R01 application to conduct a large-scale efficacy study for this population. The proposed MyPEEPS Mobile intervention for YTM is a novel and evidence-driven intervention using mobile technology to deliver HIV prevention information specifically developed for YTM. Consequently, we are confident that the proposed intervention will be of high impact intervention for improving HIV prevention behaviors in YTM and have long-term implications for overall improvement in the public’s health.