Molecular Epidemiology in Children's Environmental Health Training Program (MECEH)

儿童环境健康分子流行病学培训计划（MECEH）

• 批准号: 10410816
• 负责人: Kelly J Brunst
• 金额: $ 71.61万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-15 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10410816
• 关键词: Child; Environmental Health; Molecular Epidemiology; Training Programs

PROJECT SUMMARY / ABSTRACT The Molecular Epidemiology in Children’s Environmental Health (MECEH) Training Program began July, 2001 and is in its 20th training year. MECEH is defined as the use of biological, molecular and biostatistical measures in epidemiological research to determine how environmental exposures impact children’s health at the physiologic, behavioral, cellular, and molecular levels. The marriage of epidemiology, medicine, statistical genetics, molecular biology, molecular genetics, and molecular epidemiology serves as an umbrella for focused research in environmental epidemiology, biomarkers and genetics. MECEH has four participating departments/programs: Environmental and Public Health Sciences, Pediatrics, psychiatry and behavioral neuroscience, and the Cincinnati Medical Scientist Training Program. MECEH has had a continuous full enrollment with 27 Predoctoral and 53 Postdoctoral Fellows, including 39 MD/DO fellows. Trainees have made great professional strides with national presentations, numerous publications, grant submissions and obtaining academic, government and industrial research positions. This application requests support for 4 predoctoral and 6 postdoctoral positions each year for 2022-2027, to maintain its current size. The MECEH Training Program’s long-term objective is to continue to increase the number of cross-trained epidemiologists, physician-scientists, biostatisticians, and molecular biologists who investigate high impact issues related to environmental exposures and complex childhood diseases. The overarching rationale for this program is that training in molecular epidemiology is not only vital to our understanding of the origin of complex disease by providing clues regarding specific mechanisms, molecules and genes that influence risk but also provides a framework for interdisciplinary training for a new generation of pediatric researchers to perform this work. Thus, the MECEH Training Program has three primary goals: 1) provide a strong grounding in epidemiologic, biostatistical, and molecular methods; 2) prepare students for interdisciplinary research and “enhance clinical research workforce training,” as stated in the NIH roadmap; 3) expand growth areas for epidemiological training in epigenomics/’omics’ and community based participatory research; and 4) provide career development programming to promote career success and sustainability. These goals are achieved through the recruitment of high quality applicants, including underrepresented minorities, leadership and mentorship by a core of nationally- and internationally- renowned scientists, support by research-intensive departments; well-funded scientific programs and centers; and advise from a distinguished and enthusiastic External Advisory Board.

项目总结/摘要 儿童环境卫生分子流行病学（MECEH）培训计划于2001年7月开始 这是它的第20个训练年。MECEH被定义为使用生物、分子和生物统计学 流行病学研究中确定环境暴露如何影响儿童健康的措施， 生理、行为、细胞和分子水平。流行病学、医学、统计学的结合 遗传学、分子生物学、分子遗传学和分子流行病学是一个保护伞， 重点研究环境流行病学、生物标志物和遗传学。MECEH有四个参与 部门/计划：环境和公共卫生科学，儿科，精神病学和行为 神经科学和辛辛那提医学科学家培训计划。MECEH已连续满 招生与27名博士预科和53名博士后研究员，包括39名MD/DO研究员。学员们 在国家演讲、众多出版物、赠款提交和获得 学术、政府和工业研究职位。此应用程序请求支持4个博士预科 2022-2027年每年6个博士后职位，以保持现有规模。 MECEH培训计划的长期目标是继续增加交叉培训的人数， 流行病学家、医学科学家、生物统计学家和分子生物学家， 与环境暴露和复杂的儿童疾病有关的问题。最重要的理由是， 分子流行病学的培训不仅对我们理解复杂的 通过提供有关影响风险的特定机制、分子和基因的线索， 为新一代儿科研究人员提供了跨学科培训的框架， 工作因此，MECEH培训计划有三个主要目标：1）提供一个坚实的基础， 流行病学，生物统计学和分子方法; 2）为跨学科研究做好准备， “加强临床研究劳动力培训，”正如NIH路线图所述; 3）扩大增长领域， 表观基因组学/“组学”和基于社区的参与性研究方面的流行病学培训;以及4）提供 职业发展方案，以促进职业成功和可持续性。实现这些目标 通过招聘高素质的申请人，包括代表性不足的少数民族，领导和 由国内和国际知名科学家的核心指导，由研究密集型 部门;资金充足的科学计划和中心;并建议从一个杰出的和热情的 外部咨询委员会。