Molecular Epidemiology in Children's Environmental Health Training Program

儿童环境健康分子流行病学培训项目

• 批准号: 7650233
• 负责人: Grace LeMasters
• 金额: $ 48.22万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-15 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7650233
• 关键词: Child; Environmental Health; Molecular Epidemiology; Training Programs; health training

DESCRIPTION (provide by applicant) The Molecular Epidemiology in Children's Environmental Health (MECEH) training program began July, 2001 and is in its fourth training year. MECEH is defined as the use of biological, molecular and statistical measures in epidemiological research to determine how environmental exposures impact children's health at the physiologic, cellular, and molecular levels. As the offspring of epidemiology, medicine, statistical genetics, molecular biology, and molecular genetics, molecular epidemiology serves as an umbrella for focused research in genetic and biomarker epidemiology. MECEH has 3 participating departments: Environmental Health, Pediatric Medicine and Molecular Genetics. MECEH has had continuous full enrollment with 17 trained, 6 pre-doctoral, 8 M.D./MS fellows and 3 Ph.D./M.D. postdoctoral trainees. Seven have finished or are finishing by summer 2005 and have made great professional strides with national presentation, numerous publications, grant submissions and obtaining academic research positions. This application requests support for 3 additional trainees for the 5-years from 2006 to 2011, 1 pre-doctoral and 2 postdoctoral positions. The MECEH's long term objective is to increase the number of cross-trained epidemiologists, physician epidemiologists and molecular biologists who investigate high impact issues related to environmental exposures and complex childhood diseases. The overarching rationale for this training program has been stated in such federal initiatives as the Children's Health Act of 2000 (H.R.4365) which stressed "investment in tomorrow's pediatric researchers" (sec 1002). The MECEH has 3 primary goals: 1) provide a strong grounding in epidemiologic, statistical and wet and dry laboratory molecular methods, 2) prepare students for interdisciplinary research training and "enhance clinical research workforce training" as stated in the NIH roadmap, and 3) expand the trainee's expertise in statistical genomics, a rapidly developing area and a newer direction for this program. The public health significance of the MECEH program is directly correlated to the increasing national awareness of the rising number of environmentally related disease such as diabetes, obesity, asthma, neurodevelopmental disorders, and prematurity among others. Thus, the public health relevance of the program is great and is directly related to the need for researchers knowledgeable across disciplines in cutting-edge methodologies in the area of pediatric environmental health.

描述（由申请人提供） 儿童环境健康分子流行病学（MECEH）培训项目于2001年7月开始，目前已是第四个培训年。 MECEH 被定义为在流行病学研究中使用生物、分子和统计措施来确定环境暴露如何在生理、细胞和分子水平上影响儿童的健康。 作为流行病学、医学、统计遗传学、分子生物学和分子遗传学的产物，分子流行病学是遗传和生物标志物流行病学重点研究的总括。 MECEH 有 3 个参与科室：环境健康科、儿科科和分子遗传学科。 MECEH 已连续招生满员，共有 17 名受过培训的人员、6 名博士前人员、8 名医学博士/硕士研究员和 3 名博士/医学博士。博士后实习生。到 2005 年夏天，其中七人已完成或即将完成，并在全国演讲、大量出版物、拨款申请和获得学术研究职位方面取得了巨大的专业进步。本申请要求在 2006 年至 2011 年 5 年间增加 3 名实习生、1 名博士前职位和 2 名博士后职位。 MECEH 的长期目标是增加经过交叉培训的流行病学家、医师流行病学家和分子生物学家的数量，他们研究与环境暴露和复杂儿童疾病相关的高影响问题。该培训计划的总体原理已在《2000 年儿童健康法案》(H.R.4365) 等联邦举措中得到阐述，该法案强调“对未来儿科研究人员的投资”（第 1002 条）。 MECEH 有 3 个主要目标：1) 为流行病学、统计和干湿实验室分子方法奠定坚实的基础，2) 为学生做好跨学科研究培训和“加强临床研究人员培训”的准备，如 NIH 路线图所述，3) 扩大学员在统计基因组学方面的专业知识，统计基因组学是一个快速发展的领域，也是该项目的新方向。 MECEH 计划对公共卫生的重要性与国民对日益增多的环境相关疾病（如糖尿病、肥胖、哮喘、神经发育障碍和早产等）的认识的提高直接相关。因此，该计划与公共卫生的相关性很大，并且与对儿科环境健康领域跨学科前沿方法学知识的研究人员的需求直接相关。