Molecular Epidemiology in Children's Environmental Health Training Program

儿童环境健康分子流行病学培训项目

• 批准号: 7468402
• 负责人: Grace LeMasters
• 金额: $ 57.6万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-15 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7468402
• 关键词: Training Programs; environmental toxicology

DESCRIPTION (provide by applicant) The Molecular Epidemiology in Children's Environmental Health (MECEH) training program began July, 2001 and is in its fourth training year. MECEH is defined as the use of biological, molecular and statistical measures in epidemiological research to determine how environmental exposures impact children's health at the physiologic, cellular, and molecular levels. As the offspring of epidemiology, medicine, statistical genetics, molecular biology, and molecular genetics, molecular epidemiology serves as an umbrella for focused research in genetic and biomarker epidemiology. MECEH has 3 participating departments: Environmental Health, Pediatric Medicine and Molecular Genetics. MECEH has had continuous full enrollment with 17 trained, 6 pre-doctoral, 8 M.D./MS fellows and 3 Ph.D./M.D. postdoctoral trainees. Seven have finished or are finishing by summer 2005 and have made great professional strides with national presentation, numerous publications, grant submissions and obtaining academic research positions. This application requests support for 3 additional trainees for the 5-years from 2006 to 2011, 1 pre-doctoral and 2 postdoctoral positions. The MECEH's long term objective is to increase the number of cross-trained epidemiologists, physician epidemiologists and molecular biologists who investigate high impact issues related to environmental exposures and complex childhood diseases. The overarching rationale for this training program has been stated in such federal initiatives as the Children's Health Act of 2000 (H.R.4365) which stressed "investment in tomorrow's pediatric researchers" (sec 1002). The MECEH has 3 primary goals: 1) provide a strong grounding in epidemiologic, statistical and wet and dry laboratory molecular methods, 2) prepare students for interdisciplinary research training and "enhance clinical research workforce training" as stated in the NIH roadmap, and 3) expand the trainee's expertise in statistical genomics, a rapidly developing area and a newer direction for this program. The public health significance of the MECEH program is directly correlated to the increasing national awareness of the rising number of environmentally related disease such as diabetes, obesity, asthma, neurodevelopmental disorders, and prematurity among others. Thus, the public health relevance of the program is great and is directly related to the need for researchers knowledgeable across disciplines in cutting-edge methodologies in the area of pediatric environmental health.

描述（申请人提供） 儿童环境卫生分子流行病学（MECEH）培训计划于2001年7月开始，目前已进入第四个培训年。 MECEH被定义为在流行病学研究中使用生物、分子和统计措施，以确定环境暴露如何在生理、细胞和分子水平上影响儿童健康。 作为流行病学、医学、统计遗传学、分子生物学和分子遗传学的产物，分子流行病学是遗传学和生物标志物流行病学的重点研究领域。 MECEH有3个参与部门：环境卫生，儿科医学和分子遗传学。 MECEH已连续满招17培训，6博士预科，8 M.D./硕士研究员和3名博士/ M.D.博士后研究生。到2005年夏季，有7个国家已经完成或正在完成学业，并在专业方面取得了很大的进步，在国家一级发表了论文，发表了许多论文，提交了赠款，并获得了学术研究职位。该申请要求在2006年至2011年的5年中支持3名额外的受训人员，1名博士前和2名博士后职位。 MECEH的长期目标是增加交叉培训的流行病学家，医生流行病学家和分子生物学家的数量，他们调查与环境暴露和复杂儿童疾病有关的高影响问题。这项培训计划的总体原理已在联邦倡议中阐明，如2000年儿童健康法（H.R.4365），强调“投资于明天的儿科研究人员”（第1002节）。MECEH有3个主要目标：1）提供流行病学，统计学和干湿实验室分子方法的坚实基础，2）为跨学科研究培训和“加强临床研究劳动力培训”做好准备正如NIH路线图所述，以及3）扩大受训者在统计基因组学方面的专业知识，这是一个快速发展的领域，也是该计划的新方向。 MECEH计划的公共卫生意义与国民对糖尿病、肥胖症、哮喘、神经发育障碍和早产等环境相关疾病数量不断增加的认识直接相关。因此，该计划的公共卫生相关性是巨大的，并直接关系到需要跨学科的研究人员在儿科环境健康领域的尖端方法。