One treatment, multiple targets: Prism adaptation and left brain stroke rehabilitation

一种治疗,多个目标:棱镜适应和左脑中风康复

基本信息

  • 批准号:
    10411926
  • 负责人:
  • 金额:
    --
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2020
  • 资助国家:
    美国
  • 起止时间:
    2020-07-01 至 2023-06-30
  • 项目状态:
    已结题

项目摘要

Stroke is the most frequent cause of US adult disability, and post-acute stroke care is among the fastest-growing expense categories. The functional disability experienced by Veterans after stroke, and the limited rehabilitation resources available, highlight the importance of identifying feasible treatments acting on more than one recovery target. Currently, cognitive and motor impairments, and pain, are addressed with separate and modality-specific treatment pathways. As a result, Veteran stroke survivors are vulnerable to a fragmented interprofessional care process, with under-treatment of some disabling conditions and failure to coordinate synergistic interventions. This fragmented care process leads to longer hospital stays, greater risk of falls and accidents, incomplete recovery and poor quality of life. Our overall objective in this project is to employ prism adaptation treatment (PAT), a 10-day regimen reported to enhance spatial function, motor recovery, and reduce post-stroke pain. Although spatial-motor-sensory impairments are common in both left and right brain stroke, previous studies of PAT have only included right-brain stroke survivors. A potential barrier to broad implementation of PAT as a multi-target treatment in stroke rehabilitation, is lack of evidence for the feasibility of assessment and treatment procedures in patients with left-brain stroke who often experience co-morbid language disorder (aphasia) and memory impairments. We propose the first study of PAT in subacute left-brain stroke patients with aphasia and memory deficits to systematically investigate the feasibility of using adapted PAT procedures (Aim 1) and adapted spatial-motor- sensory assessments (Aim 2), which is a prerequisite to conducting a full-scale clinical trial. Additionally, previous brain-mapping studies have shown that lesion patterns can be used to identify patients who respond optimally to PAT. Thus, we also seek to establish a clinically accessible, reliable way of categorizing lesion location (Aim 3), a prerequisite for broad implementation of clinical guidelines about patient selection for PAT. In the proposed study, we will collect and analyze data on four key areas of feasibility, including acceptability, implementation, adaptation and limited efficacy. Our long-term goal is to implement PAT in both left and right-brain stroke rehabilitation to simultaneously improve cognitive and motor function, and pain. By demonstrating the feasibility of adapted assessment and treatment procedures in left-brain stroke patients with aphasia and memory impairment, and the feasibility and reliability of clinically accessible lesion categorization methods, we will open a path to a full-scale investigation of PAT as a multi-target treatment stroke rehabilitation. This line of research has the potential to increase the efficiency and effectiveness of currently fragmented care processes and significantly improve functioning, independence and quality of life in thousands of Veterans with stroke-related disabilities.
中风是美国成年人残疾的最常见原因,急性中风后的护理是其中之一

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Motivation as a Predictor of Aphasia Treatment Outcomes: A Scoping Review.
动机作为失语症治疗结果的预测因子:范围界定审查。
  • DOI:
    10.1097/tld.0000000000000286
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    1.4
  • 作者:
    Weatherill,Maryanne;Tibus,Elizabeth;Rodriguez,AmyD
  • 通讯作者:
    Rodriguez,AmyD
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Amy D Rodriguez其他文献

Effects of Gesture and Semantic-Phonologic Treatments for Verb Retrieval
手势和语义语音处理对动词检索的影响
  • DOI:
  • 发表时间:
    2005
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Amy D Rodriguez;A. Raymer;L. Rothi
  • 通讯作者:
    L. Rothi
Aphasia Rehabilitation Service Delivery in a Stroke Rehabilitation Unit in Australia: A Clinical Audit of Speech Pathology Practices
澳大利亚中风康复中心失语症康复服务的提供:言语病理学实践的临床审核
People with aphasia share their views on self-management and the role of technology to support self-management of aphasia
失语症患者分享他们对自我管理的看法以及技术在支持失语症自我管理中的作用
  • DOI:
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    2.2
  • 作者:
    L. Nichol;S. Wallace;Rachelle Pitt;Amy D Rodriguez;Zhi Zhi Diong;Annie J Hill
  • 通讯作者:
    Annie J Hill
Apraxia of Speech: Change in Error Consistency Following a Multimodal intensive Treatment (MMiT)
言语失用症:多模式强化治疗 (MMiT) 后错误一致性的变化
  • DOI:
  • 发表时间:
    2011
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Dana M Szeles;S. Harnish;Amy D Rodriguez;Fletcher Bowden;Stephanie Uhazie;J. Gilbert;Courtney Hamm;J. Rosenbek;Tiffany Fernandes;B. Crosson;L. Gonzalez;T. Conway
  • 通讯作者:
    T. Conway
Crosswalk of participation self-report measures for aphasia to the ICF: what content is being measured?
向 ICF 提供失语症参与自我报告测量的 Crosswalk:正在测量哪些内容?
  • DOI:
  • 发表时间:
    2015
  • 期刊:
  • 影响因子:
    2.2
  • 作者:
    C. Brandenburg;L. Worrall;Amy D Rodriguez;Karl S. Bagraith
  • 通讯作者:
    Karl S. Bagraith

Amy D Rodriguez的其他文献

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{{ truncateString('Amy D Rodriguez', 18)}}的其他基金

One treatment, multiple targets: Prism adaptation and left brain stroke rehabilitation
一种治疗,多个目标:棱镜适应和左脑中风康复
  • 批准号:
    10016838
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
Intention Treatment for Anomia: Investigating Dose Frequency Effects and Predictors ofTreatment Response to Improve Efficacy and Clinical Translation
失智症的意向治疗:研究剂量频率效应和治疗反应的预测因素,以提高疗效和临床转化
  • 批准号:
    10597989
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
One treatment, multiple targets: Prism adaptation and left brain stroke rehabilitation
一种治疗,多个目标:棱镜适应和左脑中风康复
  • 批准号:
    10183359
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
Intention Treatment for Anomia: Investigating Dose Frequency Effects and Predictors of Treatment Response to Improve Efficacy and Clinical Translation
失智症的意向治疗:研究剂量频率效应和治疗反应的预测因素,以提高疗效和临床转化
  • 批准号:
    10112761
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
Intention Treatment for Anomia: Investigating Dose Frequency Effects and Predictors ofTreatment Response to Improve Efficacy and Clinical Translation
失智症的意向治疗:研究剂量频率效应和治疗反应的预测因素,以提高疗效和临床转化
  • 批准号:
    10382269
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
Acute Exercise Effects on Word Learning in Aging and Stroke-induced Aphasia
急性运动对衰老和中风引起的失语症的单词学习的影响
  • 批准号:
    9242454
  • 财政年份:
    2016
  • 资助金额:
    --
  • 项目类别:

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