Pilot Project Program

项目总结(试点项目计划) OCSB试点项目方案的目标是：(1)为研究人员提供项目支助，以便获得 将增强其外部赠款竞争力的结构生物学相关项目的初步数据 (Ii)加强有组织及三合会资助的核心设施的用户基础；(Iii)继续支持及早- 阶段调查人员，以及(Iv)激励合作研究。在第一阶段和第二阶段，有组织及严重罪行科资助了16 种子或试点项目，导致向这些调查人员发放14份出版物和22份新的外部赠款； 这相当于这笔投资的11.7倍回报。我们打算继续我们的开放和竞争试点 OCSB第三阶段的项目计划。我们将从早期开始优先考虑创新和有价值的项目- 阶段研究人员，也鼓励结构生物学家和非结构生物学家之间的合作 作为促进我们科布雷核心设施的使用。指导和培训是我们中心的标志，将继续下去 为我们拟议的试点项目的成功做出贡献。我们特别感兴趣的是 新的结构生物学技术，包括冷冻-EM，纳入了我们的研究计划和其他中心 参与者。

Project Summary (Pilot Project Program) The objectives of the OCSB Pilot Project Program are to: (i) provide project support for researchers to obtain preliminary data for structural biology-related projects that will enhance competitiveness of their external grant applications, (ii) enhance the user base of the OCSB-supported core facilities, (iii) continue to support early- stage investigators, and (iv) incentivize collaborative research. During Phases 1 and 2, the OCSB funded 16 seed or pilot projects that resulted in 14 publications and 22 new external grants awarded to these investigators, which represents a 11.7-fold return on the investment. We intend to continue our open and competitive pilot project program during Phase 3 of the OCSB. We will prioritize innovative and meritorious projects from early- stage investigators, encourage collaborations between structural biologists and non-structural biologists, as well as promote the use of our COBRE core facilities. Mentorship and training, hallmarks of our center, will continue to contribute to the success of our proposed pilot project program. We are particularly interested in incorporating new structural biology techniques, including cryo-EM, into the research programs of our PPLs and other center participants.