Administrative core

行政核心

• 批准号: 10415105
• 负责人: Johann Eli Gudjonsson
• 金额: $ 21.87万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-06-01 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10415105
• 关键词: Address; Advisory Committees; Animal Model; Area; Award; Big Data; Biology; Cell Culture Techniques; Clinic; Collaborations; Communication; Communities; Cutaneous; Dermatology; Development; Disease; Effectiveness; Electronic Mail; Ensure; Environment; Evaluation; Fostering; Funding; Genetically Engineered Mouse; Goals; Grant; Health; Individual; Inflammatory; Infrastructure; Institution; Knowledge; Lead; Leadership; Mentors; Michigan; Mission; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Newsletter; Pathogenesis; Patients; Personnel Management; Recording of previous events; Research; Research Activity; Research Infrastructure; Research Personnel; Resources; Schools; Science; Series; Services; Skin; Surveys; System; Training; Translating; Travel; Universities; Visit; Work; base; improved; innovation; interest; member; model design; operation; programs; skin disorder; success; symposium; tool; web site

The University of Michigan Department of Dermatology has a long history of productive research in areas highly relevant to the NIAMS mission but there are untapped opportunities for engagement with multiple investigators outside of the department whose interests are also highly relevant to skin biology and disease. Cross-cutting collaborations are particularly important in this era of team science, when groups with deep knowledge in defined areas can work together to collectively address fundamental questions in basic biology and disease that would be difficult, if not impossible, to tackle in individual labs. The proposed University of Michigan Skin Biology and Diseases Resource-based Center (UM-SBDRC) will provide investigators at Michigan, and several other institutions, access to outstanding Resource Cores and Center activities. The ultimate goals of the Center include facilitating independently-funded research into skin biology and disease, with an emphasis on inflammatory skin disorders; fostering the development of team-science, combining big- data approaches with functional studies in cell culture and genetically-engineered mouse models; and attracting additional investigators into cutaneous research relevant to the NIAMS mission. The UM-SBDRC Administrative Core will coordinate Center activities and oversee management of the Resource Cores. It will achieve this by 1) establishing a strong leadership and support team, 2) building an effective set of committees to assist with Center and Resource Core administration, 3) fostering effective interactions with Resource Cores, 4) optimizing financial administration throughout the Center, and 5) developing survey tools and metrics to assess Center and Resource Core effectiveness. The Administrative Core will also build an effective communications platform, which will include a dedicated, interactive UM-SBDRC website, a biannual newsletter, and program and informational emails. In addition, to enhance the research environment and provide greater opportunities for member interaction and collaboration, the Administrative Core will build a robust Enrichment Program. This will include 1) a Pilot & Feasibility Program, 2) Mentoring Program, 3) Travel Award Program, 4) quarterly Visiting Speaker Series, and 5) Annual Symposium. As a result of these Center activities and the outstanding training and services provided by the Resource Cores, the UM-SBDRC will have a powerful and sustained impact on cutaneous biology research at the University of Michigan and elsewhere. The Center will facilitate skin-related research activities by its 50 members, help bring new investigators into the field, enhance research infrastructure for improved communication and scientific interactions, significantly increase the visibility of the cutaneous research community at the University of Michigan, and lead to major new research initiatives and external support for team-science projects relevant to the NIAMS mission. Ultimately, the research infrastructure and programs provided through the UM-SBDRC will help translate basic discoveries from the lab to the clinic, improving the health of patients with a variety of skin disorders.

密歇根大学皮肤病学系在该领域的生产性研究方面有着悠久的历史 与NIAMS任务高度相关，但仍有尚未开发的机会与多个 部门外的研究人员，他们的兴趣也与皮肤生物学和疾病高度相关。 在这个团队科学的时代，交叉协作尤为重要，因为团队拥有深度的 特定领域的知识可以共同解决基础生物学中的基本问题 以及疾病，这些疾病即使不是不可能，也很难在单独的实验室中攻克。拟建的香港中文大学 密歇根皮肤生物学和疾病资源中心(UM-SBDRC)将在 密歇根州和其他几个机构，获得优秀的资源核心和中心活动。这个 该中心的最终目标包括促进独立资助的皮肤生物学和疾病研究， 强调炎症性皮肤病；促进团队科学的发展，结合大科学 细胞培养和基因工程小鼠模型的功能研究的数据方法；以及 吸引更多的研究人员参与与NIAMS任务相关的皮肤研究。UM-SBDRC 管理核心将协调中心的活动并监督资源核心的管理。会的 要做到这一点，1)建立一个强大的领导和支持团队，2)建立一套有效的委员会 协助中心和资源核心管理，3)促进与资源的有效互动 核心，4)优化整个中心的财务管理，5)开发调查工具和指标 评估中心和资源的核心有效性。行政核心也将构建一个有效的 通信平台，其中将包括一个专门的、互动的UM-SBDRC网站，每两年一次 时事通讯，以及计划和信息电子邮件。此外，为了改善研究环境和 为成员互动和协作提供更多机会，行政核心将建立 强健的浓缩计划。这将包括1)试点和可行性计划，2)指导计划，3)旅行 颁奖计划，4)季度访问演讲者系列，5)年度研讨会。这些中心的结果 活动以及资源核心提供的杰出培训和服务，UM-SBDRC将拥有 对密歇根大学和其他地方的皮肤生物学研究产生了强大而持久的影响。 该中心将促进其50名成员的皮肤相关研究活动，帮助引入新的研究人员 加强研究基础设施，以改善交流和科学互动， 提高密歇根大学皮肤研究社区的知名度，并导致主要 为与NIAMS任务相关的团队科学项目提供新的研究倡议和外部支持。 最终，通过UM-SBDRC提供的研究基础设施和计划将有助于将BASIC 从实验室到临床的发现，改善了各种皮肤病患者的健康状况。