Studies on Antimicrobial resistance in bacteria of veterinary importance

项目摘要/摘要 纽约州/康奈尔动物健康诊断中心(Ahdc)是一个全方位的多学科服务中心 兽医诊断实验室，也是美国东北部唯一的兽医诊断实验室。阿赫德克 2016年收到了20多万份客户申请。细菌科有MALDI-TOF，敏感度，血液 培养机、BSL3可升级工作区和16S DNA测序功能，使其成为全方位服务 细菌学实验室。此外，AHDC拥有内部ISO批准的全基因组测序 这是传染病实验室独有的能力。美国食品和药物管理局细菌学实验室 2016年对临床样本、组织、血清、细菌分离株进行了大约100,000次测试， 环境、食品和饲料样品。美国食品和药物管理局与食品和药物管理局合作，并在 在过去的十几年里，宠物食品和动物饲料污染调查多次。我们希望 继续参与FDA Vet-LIRN计划和其他网络实验室，以： 1)继续参加VPO指定的样本分析和监督活动，以促进 动物健康和福利，并增加兽医-LIRN网络的紧急援助能力 以及大规模的疫情检测。 2)通过开发和使用标准化方法，提供支持监管行动的分析数据； 设备平台和报告方法，继续参加由 VPO，应VPO的要求继续调查消费者报告的案件，并继续 改进和实施VPO指定的标准化质量管理体系。 3)继续参与小规模抗生素敏感性测试研究，以解决新出现的问题 抗菌素耐药性问题，并参与全基因组测序项目。 AHDC细菌科打算继续与FDA Vet-LIRN、Vet-LIRN和Vet-LIRN合作。 LIRN网络，以及联邦、州、地方和部落组织，以促进动物健康以及饲料和食物 安全和安保。

Project Summary/Abstract The New York State/Cornell Animal Health Diagnostic Center (AHDC) is a full-service multidisciplinary veterinary diagnostic laboratory and the only one of its kind in the northeastern United States. The AHDC received over 200,000 client accessions in 2016. The Bacteriology section has MALDI-TOF, Sensititer, Blood culture machine, BSL3 upgradable workspace and 16S DNA sequencing capabilities, making it a full-service bacteriology laboratory. Additionally, the AHDC has in-house ISO approved Whole genome sequencing capacity which are unique to infectious disease laboratories. The Bacteriology laboratory of the AHDC performed approximately 100,000 tests in the year 2016 on clinical samples, tissue, serum, bacterial isolates, environmental, food, and feed samples. The AHDC has partnered with the FDA and played an active role in pet food and animal feed contamination investigations many times over the past dozen years. We hope to continue our participation with the FDA Vet-LIRN program and other network laboratories to: 1) Continue participation in VPO designated sample analyses and surveillance activities to promote animal health and welfare and add to the Vet-LIRN Network's surge capacity to assist in emergency and large-scale outbreak testing. 2) Provide analytical data to support regulatory actions by developing and using standardized methods, equipment platforms, and reporting methods, continued participation in proficiency testing provided by the VPO, continue investigating consumer reported cases as requested by the VPO, and continuing to improve and implement standardized quality management systems as designated by the VPO. 3) Continue to participate in small-scale antibiotic susceptibility testing studies to address emerging antimicrobial resistance issues, and participate in Whole genome sequencing project. The bacteriology section of the AHDC intends to continue cooperative activities with the FDA Vet-LIRN, the Vet- LIRN network, and federal, state, local and tribal organizations to promote animal health and feed and food safety and security.