Building Interdisciplinary Research Careers in Women's Health

项目摘要 这是杜兰BIRCWH计划的竞争续订申请，该计划已成功培训了 在种族/族裔和专业上不同的妇女健康跨学科研究人员群体-- 在过去的4年里，杜兰大学提高了对妇女健康研究的认识。我们现在建议在此基础上 我们以往的成功，扩大和加强了BIRCWH项目基础。长期目标是增加 受过高度培训的具有文化能力的独立跨学科调查员的数量和多样性 妇女健康，重点是心血管疾病领域的性别/性别差异研究 心血管疾病(CVD)、传染病(ID)和神经科学(NS)。该计划将重点关注CVD、ID和NS BE- 这些疾病对妇女的影响的原因、关于性别/性别差异的现有知识差距 整个研究领域，以及杜兰大学这些领域的实力。我们成功的关键组件 职业发展计划包括1)为特定学者需求量身定做的教学课程；2)个性化教学-- REER发展培训；3)BIRCWH系列研讨会；4)正在进行的会议；5)所需拨款和SCI- 专门的写作和项目管理研讨会；6)指导跨学科研究；7)负责协调 研究训练中的管道。创新的方法包括根据学者计划的需要使用Self- 功效评估和职业发展计划，并对每位学者采用网络辅导模式， 包括基础科学和临床研究方面的专业知识。学者们立即接触到研究 并被指导及早建立学术记录，并通过交流获得演示和组织技能 积极参加健康科学研究日--妇女健康/性别差异科。新的COM- 增强的BIRCWH计划的主要内容包括利用最近成立的杜兰大学扩大产能 性别生物学和医学卓越中心(TCESBM)；增加教职员工对前 ID和NS的细分领域；在团队科学和公平、多样性和包容性方面建立学者能力 (EDI)研究；促进对性/性别与社会决定因素之间相互作用的理解 健康(SDOH)。学者们将从BASCH(细胞、分子和分子)那里学习尖端的研究方法和技能。 从理论、遗传学)，到床边(临床研究、临床试验)，再到人口(流行病学、预防、健康 服务研究)，并在有指导的现有实验室/小组中进行自己的研究项目， 解决2019-2023年跨NIH妇女健康再战略计划的跨学科环境 搜索。学者的跨学科研究将集中在心血管疾病、ID、NS和广告方面的性别/性别差异。 着装主题(寿命、性别/性别决定因素、健康差异、跨学科研究)。 我们建议培训6名教师学者，为期2-3年(内科科学家通常为3年)。正在进行中，COM- 综合评估将指导改进该计划在衔接研究方面所展示的成功 初级学者的培训和研究独立性侧重于心血管疾病、ID和NS的性别/性别差异。

Project Summary This is a competing renewal application for the Tulane BIRCWH Program, which has successfully trained a racially/ethnically and professionally diverse group of interdisciplinary researchers in women’s health and in- creased awareness of women’s health research at Tulane over the last 4 years. We propose now to build on our prior success and expand and reinforce the BIRCWH program base. The long-term goal is to increase the number and diversity of highly trained culturally competent, independent, interdisciplinary investigators in Women’s Health with an emphasis on Sex/Gender Differences research in the fields of cardiovascular dis- ease (CVD), infectious disease (ID) and neuroscience (NS). The program will focus on CVD, ID and NS be- cause of the impacts of these diseases on women, the existing knowledge gaps on the sex/gender differences across the research spectrum, and the strength of these areas at Tulane. Key components of our successful career development plan include 1) didactic courses tailored to specific Scholar needs; 2) individualized ca- reer development training; 3) BIRCWH seminar series; 4) Work-in-Progress sessions; 5) required grant & sci- entific writing and project management workshops; 6) mentored interdisciplinary research; 7) responsible con- duct in research training. The innovative approach includes tailoring the program to Scholars needs using self- efficacy assessment and career development plans, and using a network mentoring model for each Scholar, including expertise in both basic science and clinical research. Scholars are immediately exposed to research and are guided to establish a scholarly track record early, and gain presentation and organization skills by ac- tive participation in the Health Sciences Research days-Women’s Health/Sex Differences Section. New com- ponents of the enhanced BIRCWH program include expanding capacity with the recently established Tulane Center of Excellence in Sex-based Biology and Medicine (TCESBM); increasing faculty participation in ex- panded fields of ID and NS; building Scholar competence in team science and equity,diversity, and inclusion (EDI) in research; and advancing understanding of the interplay between sex/gender with social determinants of health (SDOH). The Scholars will learn cutting-edge research methods and skills from Bench (cellular, mo- lecular, genetics), to Bedside (clinical research, clinical trials) to Population (epidemiology, prevention, health services research) and conduct their own research projects in established laboratories/groups in a mentored, interdisciplinary environment that address the 2019-2023 Trans-NIH Strategic Plan for Women’s Health Re- search. Scholar’s interdisciplinary research will focus on sex/gender differences in CVD, ID, and NS and ad- dress overarching themes (lifespan, sex/gender determinants, health disparities, interdisciplinary research). We propose to train 6 faculty Scholars for 2-3 years (3 years typical for physician-scientists). Ongoing, com- prehensive evaluation will guide improvements to the program's demonstrated success in bridging research training & research independence for junior scholars focused on sex/gender differences in CVD, ID, and NS.