ACHIEVE Investigator Development Core

摘要 研究者发展核心（IDC）的总体目标是创造一种氛围， 合作和创新研究可以蓬勃发展，通过健全的健康， 研究和实施科学。IDC将为高度多样化的群体提供机会， 熟练的早期研究人员（ESI）通过有效地开发和试点创新研究 在拟议的ACHIEVE中利用三个主要研究机构的现有资源 更大IDC将提供研究设计和生物统计学方面的培训和咨询， 种子资金计划，并促进获得关键基础设施，包括库存生物标本， 电子健康记录和一系列数据位于新开发的韦恩州 大学（WSU）基于Google云的数据仓库，摄取和传播平台。的 IDC的核心职能是促进试点项目获奖者的研究事业， 非常有竞争力的申请人竞争激烈的校外支持。IDC将特别鼓励 来自不同学科和背景的早期研究人员专注于慢性病 提高劳动力的多样性。IDC的具体目标是规划每年的 通过我们的社区顾问和ACHIEVE GREATER计划的投入获得资助机会 领导人的人选信号该计划将提供给ACHIEVE GREATER会员和更广泛的韦恩 州立大学（WSU）、亨利福特卫生系统（HFHS）和凯斯西储大学 （CWRU）/大学医院（UH）研究社区。有兴趣的申请人将提交一封信， 意向书（LOI）将由科学咨询委员会（SAC）审查。的申请人 非常优秀的意向书将被邀请提交一份完整的申请，并将获得 生物统计学、研究设计、IRB和其他监管事务的行政核心。IDC将 在为期5年的“成就更大”资助周期中，每年提供6笔新的试点项目赠款， 每项奖励包括为期一年的40 000美元资金。此外，我们将为获奖者提供 方案支助，包括IRB以及统计支助，不收取任何费用。的 IDC主任（Safwan Badr博士- WSU）和助理主任（Sadeer Al-Kindi博士- CWRU）将 监督一个咨询小组，该小组定期与ACHIEVE GREATER试点项目接受者会面， 审查进展并提供指导。最后，我们将跟踪包括出版物在内的成功措施 和竞争激烈的校外奖项。总体而言，IDC将培育和支持转型 开展对人群健康有利的慢性病预防研究。

Abstract The overarching goal of the Investigator Development Core (IDC) is to create a climate where collaborative and innovative research can thrive, leading to improved population health through sound research and implementation science. The IDC will provide opportunities for a diverse cohort of highly skilled early-stage investigators (ESI) to develop and pilot innovative research studies by efficiently leveraging existing resources across three major research institutions in the proposed ACHIEVE GREATER. The IDC will provide training and consultation on study design and biostatistics, provide a seed funding program, and facilitate access to key infrastructure including banked biospecimens and electronic health records, and an array of data located in the newly developed Wayne State University (WSU) Google-Cloud-based data warehouse, ingestion, and dissemination platform. The core function of the IDC is to promote the research careers of the pilot project awardees to become highly competitive applicants for competitive extramural support. The IDC will specifically encourage early-stage investigators from different disciplines and backgrounds to focus on chronic disease disparities to enhance workforce diversity. The specific aims of the IDC are to plan each year's funding opportunity with input from our community advisors and ACHIEVE GREATER program leaders. This program will be available to the ACHIEVE GREATER membership and broader Wayne State University (WSU), Henry Ford Health System (HFHS) and Case Western Reserve University (CWRU)/University Hospitals (UH) research communities. Interested applicants will submit a letter of intent (LOI) which will be reviewed by the Scientific Advisory Committee ( SAC). Applicants with highly meritorious LOIs will be invited to submit a full application and will receive assistance from the administrative core on biostatistics, study design, IRB and other regulatory matters. The IDC will award six new pilot project grants each year of the 5-year ACHIEVE GREATER funding cycle with each award including funds of $40,000 over a 1-year period. In addition, we will provide awardees with programmatic support, which includes IRB as well as statistical support at no cost to them. The IDC Director (Dr. Safwan Badr – WSU) and Assistant Director (Dr. Sadeer Al-Kindi – CWRU) will oversee an advisory team that meets regularly with ACHIEVE GREATER pilot project recipients to review progress and provide guidance. Finally, we will track success measures including publications and competitive extramural awards. Overall, the IDC will nurture and support transformational research on chronic disease prevention with favorable impact on population health.