Vevo 3100 Ultrasound System

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Project Summary/Abstract: The Fujifilm VisualSonics Vevo 3100 is a state of the art preclinical ultrasound imaging system that leverages a suite of features to improve image quality, acquisition time, and user experience. This instrument will provide users of the Baylor College of Medicine Mouse Metabolism and Phenotyping Core with an in vivo imaging platform suitable for mouse and rat models of disease. With this resource, core users will be able to interrogate the structure and function of the heart and blood vessels in small animals. Additionally, users will be able to interrogate internal organ and embryo morphology as well as blood perfusion of internal organs. The Vevo 3100’s improvements in image clarity, additional imaging modes such as 4D imaging, and faster acquisition rates will help users decrease technical variation related to poor image quality. Additionally, the system will help users to improve the throughput of their data acquisition and reduce biases in scoring of cardiac function through the use of artificial intelligence and machine learning algorithms to standardize measurements. Furthermore, advances in acquisition gating and image reconstruction permit the Vevo 3100 to acquire 4D images providing high temporal and spatial resolution 3D renderings of internal structures such as the heart and major blood vessels, permitting spatially unbiased assessment of these structures. The Vevo 3100 represents an exciting and necessary advance in the in vivo imaging capabilities at Baylor College of Medicine and has the potential to enhance and accelerate our research on the topics of cardiovascular and congenital disease.