Administrative Core

行政核心

• 批准号: 10430091
• 负责人: Thomas Patrick Loughran
• 金额: $ 13.69万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-10 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10430091
• 关键词: Accountability; Advisory Committees; Animal Model; Bioinformatics; Biometry; Ceramides; Clinical; Clinical Trials; Collaborations; Ensure; Goals; Institution; Laboratories; Legal patent; Manuscripts; Memorial Sloan-Kettering Cancer Center; Metabolism; Methodology; Modality; Nanotechnology; New Hampshire; Principal Investigator; Productivity; Program Research Project Grants; Progress Reports; Recommendation; Reporting; Resources; Signal Transduction; Sphingolipids; System; United States National Institutes of Health; Universities; Virginia; base; data sharing; galactosylgalactosylglucosylceramidase; glycosylation; lectures; meetings; metabolomics; nanoliposome; performance site; programs; response; success; therapeutic target

PROJECT SUMMARY The overarching goal of the Administrative Core is to oversee and coordinate all scientific, regulatory, administrative and fiscal responsibilities of the Program Project grant. The Administrative Core will accomplish its goal through the following specific aims: 1. Ensure integration of all Projects and Cores by managing all oversight strategies, including coordinating the meetings of the three committees (Executive and the External and Internal Advisory Committees) and implementing the recommendations of these Committees. 2. Realign resources based upon advice from the External and Internal Advisory Committees in collaboration with the Executive Committee (Program Leaders and Project/Core Leaders). 3. Administer and implement the multiple Principal Investigator Plan. 4. Organize the monthly meetings of the Executive Committee, annual meetings of Internal Advisory Committee, and annual meetings of External Advisory Committee. 5. Organize the P01 yearly retreat to assess overall P01 progress, based upon quantitative milestones, and plan and implement next steps making use of the reports from the Internal and External Advisory Committees. 6. Provide governance and accountability for the CAV trial 7. Provide fiscal accountability via coordination with institutional and NCI staff. 8. Document productivity of all Projects and Cores, as defined by discrete endpoints such as manuscripts, filed provisional patent applications, and invited lectures. 9. Prepare all progress reports and responses to External and Internal Advisory Committees. 10. Coordinate and oversee all scientific, regulatory, administrative, and fiscal interactions between the University of Virginia, Eastern Carolina University, Memorial Sloan Kettering Cancer Center, University of New Hampshire, and Penn State University. 11. Ensure accountability and governance of all biostatistics, bioinformatics, and “-omic” methodology across all projects and cores. 12. Coordinate Data Sharing modalities between Institutions, NIH, Nanotechnology Characterization Laboratory (NCL), and the public. 13. Coordinate the monthly Core presentations to the Executive Committee that will include descriptions of the active and pending requests for support from each Project.

项目摘要 行政核心的总体目标是监督和协调所有科学，监管， 计划项目赠款的行政和财务责任。行政核心将实现 通过以下具体目标实现其目标： 1.通过管理所有监督战略，确保所有项目和核心的整合，包括 协调三个委员会（执行委员会、外部和内部咨询委员会）的会议 （三）落实这些委员会的建议。 2.根据外部和内部咨询委员会的建议调整资源 与执行委员会（项目领导人和项目/核心）合作 领导人）。 3.管理和实施多个主要研究者计划。 4.组织执行委员会月度会议、内部委员会年度会议 咨询委员会和外部咨询委员会年度会议。 5.组织P01年度务虚会，根据定量评估P01的总体进展情况 里程碑，并计划和实施后续步骤，利用内部和 外部咨询委员会。 6.为CAV试验提供管理和问责 7.通过与机构和国家癌症研究所工作人员协调，提供财政问责制。 8.记录所有项目和核心的生产力，如离散端点所定义， 手稿，提交临时专利申请，并邀请讲座。 9.准备所有的进度报告和对外部和内部咨询委员会的回应。 10.协调和监督所有科学，监管，行政和财政之间的相互作用， 弗吉尼亚大学，东卡罗莱纳大学，纪念斯隆凯特琳癌症中心， 新罕布什尔州大学和宾夕法尼亚州立大学。 11.确保所有生物统计学、生物信息学和“-omic”的问责制和治理 所有项目和核心的方法。 12.协调机构之间的数据共享模式，NIH，纳米技术表征 实验室（NCL）和公众。 13.协调每月向执行委员会提交的核心报告，包括说明 每个项目正在处理和待处理的支助请求。