Development of a novel polysubstance assessment tool for vulnerable subpopulations

为弱势群体开发新型多物质评估工具

• 批准号: 10434816
• 负责人: Amanda M Bunting
• 金额: $ 18.17万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10434816
• 关键词: Address; Assessment tool; Award; Behavior; Communicable Diseases; Community Workers; Complement; Complex; Data; Development; Device or Instrument Development; Environment; Eye; Face; Focus Groups; Frequencies; Funding; Funding Mechanisms; Funding Opportunities; Future; General Population; Goals; Health; Health Services; Individual; Injecting drug user; Injections; Intervention; Interview; Investigation; Jail; Justice; Knowledge; Measures; Mentors; Methodology; Methods; Motivation; National Institute of Drug Abuse; New York; Opioid; Outcome; Overdose; Pattern; Persons; Pharmaceutical Preparations; Population; Positioning Attribute; Prevalence; Prisons; Property; Psychometrics; Reporting; Research; Research Personnel; Risk; Risk Assessment; Risk Behaviors; Route; Sampling; Screening procedure; Sociology; Substance Use Disorder; Surveys; Testing; Time; Training; Universities; Validation; Vulnerable Populations; adverse outcome; career; cognitive interview; contingency management; design; follow-up; heroin use; high risk; high risk population; housing instability; improved; informant; instrument; medical schools; mortality; novel; opioid overdose; opioid user; overdose death; overdose risk; polysubstance use; psychological distress; recruit; skills; substance use; therapy development; tool; tool development

PROJECT SUMMARY/ ABSTRACT The purpose of this timely and significant K01 is to provide the PI (Dr. Bunting) with the training and expertise necessary to become an independent investigator of substance use research, specializing in the development of interventions that improve health outcomes of vulnerable populations with a specific focus on polysubstance use involving opioids. Despite the prevalence of polysubstance use and its association with high-risk outcomes such as overdose, significant gaps in our understanding persist in part due to limitations of existing substance use screening and assessment tools. The ability to accurately measure polysubstance use among high-risk populations is a critical step towards developing effective strategies for improving substance-related health outcomes of this population. The overall goal of the proposal is the development of a novel polysubstance assessment tool and identification of correlates and motivations of polysubstance use behaviors among high- risk vulnerable populations. The long-term goal of this line of investigation is to develop interventions targeted to polysubstance use behaviors in vulnerable populations as an independent investigator of substance use research. To achieve this goal, the proposed award has been designed to augment the PI’s existing training in sociology and health services through a comprehensive plan that will enable her to: (1) obtain methodological skills specific to instrument development and validation, (2) enhance her ability to conduct independent research including the recruitment and retention of vulnerable populations and remote study management, and (3) develop focused skills in health services intervention development specific to vulnerable populations (i.e., persons who use substances, justice-involved). These skills will be developed at the high-impact training environment of the New York University Grossman School of Medicine with a collaborative mentoring team of nationally renowned experts. The training plan is strategically complemented by a rigorous mixed-method study. Building on prior training while expanding to new skills, the independent line of research aims to: (1) develop and test the psychometric properties of a novel assessment tool to measure polysubstance use for high-risk vulnerable populations, (2) examine the predictive validity of the novel polysubstance use assessment tool by examining risk behaviors over a 6-month period in a high-risk vulnerable population, and (3) acquire preliminary data regarding the development and acceptability of intervention strategies for polysubstance use populations. By the conclusion of this award, the PI will be positioned as a rising leader in polysubstance use research and positioned to excel in a career of polysubstance use interventions through future R-mechanism funding opportunities.

项目摘要/摘要 这一及时而重要的K01的目的是为PI(本廷博士)提供培训和专业知识 有必要成为物质使用研究的独立调查者，专门从事开发 改善弱势人群健康状况的干预措施，特别关注多种物质 涉及阿片类药物的使用。尽管多物质使用的盛行及其与高风险结果的关联 例如服药过量，我们在认识上仍然存在重大差距，部分原因是现有物质的限制 使用筛选和评估工具。在高危人群中准确测量多种物质使用情况的能力 人口是制定改善与物质相关的健康的有效战略的关键一步 这群人的结果。该提案的总体目标是开发一种新的多物质 高中生多物质使用行为的评估工具及相关因素和动机的识别 使易受伤害的人群面临风险。这项调查的长期目标是制定有针对性的干预措施 将易感人群中的多物质使用行为作为物质使用的独立调查者 研究。为了实现这一目标，拟议的奖励旨在加强PI在以下方面的现有培训 通过一个全面的计划提供社会学和卫生服务，使她能够：(1)获得方法 具备仪器开发和验证方面的专门技能，(2)增强独立指挥能力 研究，包括招募和留住弱势群体以及远程学习管理； (3)培养针对弱势人群的保健服务干预发展的重点技能(即， 使用物质的人，涉及正义)。这些技能将在高影响力的培训中得到发展 纽约大学格罗斯曼医学院的环境与合作指导团队 全国知名专家。培训计划在战略上得到了严格的混合方法的补充 学习。在先前培训的基础上，同时扩展到新技能，独立的研究方向旨在：(1) 开发和测试一种新的评估工具的心理测量学特性，以衡量多物质的使用 高危易感人群，(2)检验新的多物质使用评估的预测有效性 通过检查高危易感人群在6个月内的风险行为，以及(3)获取 关于多物质使用干预策略的制定和可接受性的初步数据 人口。到这个奖项结束时，PI将被定位为多物质使用领域的新兴领导者 研究并定位于通过未来的R-机制在多物质使用干预事业中脱颖而出 融资机会。