Development of a novel polysubstance assessment tool for vulnerable subpopulations

为弱势群体开发新型多物质评估工具

• 批准号: 10434816
• 负责人: Amanda M Bunting
• 金额: $ 18.17万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10434816
• 关键词: Address; Assessment tool; Award; Behavior; Communicable Diseases; Community Workers; Complement; Complex; Data; Development; Device or Instrument Development; Environment; Eye; Face; Focus Groups; Frequencies; Funding; Funding Mechanisms; Funding Opportunities; Future; General Population; Goals; Health; Health Services; Individual; Injecting drug user; Injections; Intervention; Interview; Investigation; Jail; Justice; Knowledge; Measures; Mentors; Methodology; Methods; Motivation; National Institute of Drug Abuse; New York; Opioid; Outcome; Overdose; Pattern; Persons; Pharmaceutical Preparations; Population; Positioning Attribute; Prevalence; Prisons; Property; Psychometrics; Reporting; Research; Research Personnel; Risk; Risk Assessment; Risk Behaviors; Route; Sampling; Screening procedure; Sociology; Substance Use Disorder; Surveys; Testing; Time; Training; Universities; Validation; Vulnerable Populations; adverse outcome; career; cognitive interview; contingency management; design; follow-up; heroin use; high risk; high risk population; housing instability; improved; informant; instrument; medical schools; mortality; novel; opioid overdose; opioid user; overdose death; overdose risk; polysubstance use; psychological distress; recruit; skills; substance use; therapy development; tool; tool development

PROJECT SUMMARY/ ABSTRACT The purpose of this timely and significant K01 is to provide the PI (Dr. Bunting) with the training and expertise necessary to become an independent investigator of substance use research, specializing in the development of interventions that improve health outcomes of vulnerable populations with a specific focus on polysubstance use involving opioids. Despite the prevalence of polysubstance use and its association with high-risk outcomes such as overdose, significant gaps in our understanding persist in part due to limitations of existing substance use screening and assessment tools. The ability to accurately measure polysubstance use among high-risk populations is a critical step towards developing effective strategies for improving substance-related health outcomes of this population. The overall goal of the proposal is the development of a novel polysubstance assessment tool and identification of correlates and motivations of polysubstance use behaviors among high- risk vulnerable populations. The long-term goal of this line of investigation is to develop interventions targeted to polysubstance use behaviors in vulnerable populations as an independent investigator of substance use research. To achieve this goal, the proposed award has been designed to augment the PI’s existing training in sociology and health services through a comprehensive plan that will enable her to: (1) obtain methodological skills specific to instrument development and validation, (2) enhance her ability to conduct independent research including the recruitment and retention of vulnerable populations and remote study management, and (3) develop focused skills in health services intervention development specific to vulnerable populations (i.e., persons who use substances, justice-involved). These skills will be developed at the high-impact training environment of the New York University Grossman School of Medicine with a collaborative mentoring team of nationally renowned experts. The training plan is strategically complemented by a rigorous mixed-method study. Building on prior training while expanding to new skills, the independent line of research aims to: (1) develop and test the psychometric properties of a novel assessment tool to measure polysubstance use for high-risk vulnerable populations, (2) examine the predictive validity of the novel polysubstance use assessment tool by examining risk behaviors over a 6-month period in a high-risk vulnerable population, and (3) acquire preliminary data regarding the development and acceptability of intervention strategies for polysubstance use populations. By the conclusion of this award, the PI will be positioned as a rising leader in polysubstance use research and positioned to excel in a career of polysubstance use interventions through future R-mechanism funding opportunities.

项目摘要/摘要 这种及时而重要的K01的目的是为PI（Bunting博士）提供培训和专业知识 成为成为物质使用研究的独立研究者所必需的，专门从事开发 改善弱势群体健康结果的干预措施，专门针对和polysubstance 使用涉及阿片类药物。尽管使用了多核电的使用及其与高风险结果的关联 例如过量服用，我们的理解差距很大，部分原因是现有主题的局限性 使用筛选和评估工具。能够准确测量高风险之间使用多物质使用的能力 人口是制定有效策略以改善与物质有关的健康的关键一步 这个人群的结果。该提案的总体目标是开发新颖的polysubstance 评估工具和识别高级polysubstance使用行为的相关性和动机 风险脆弱人群。这种调查的长期目标是制定针对的干预措施 在弱势群体中，多物质的使用行为是底物使用的独立研究者 研究。为了实现这一目标，拟议的奖项旨在增强PI现有的培训 通过一项综合计划，社会学和卫生服务将使她能够：（1）获得方法论学 特定于仪器开发和验证的技能，（2）增强了她独立进行独立的能力 研究包括招募和保留脆弱人群和远程研究管理以及 （3）在卫生服务干预开发方面发展专注的技能，特定于弱势群体（即 使用物质的人，涉及正义的人）。这些技能将在高影响力培训中发展 纽约大学格罗斯曼医学院的环境与一个合作心理团队 全国知名的专家。严格的混合方法从战略上完成培训计划 学习。在先前培训的同时，在扩展到新技能的同时，独立研究线的目的是：（1） 开发和测试一种新型评估工具的心理测量特性，以测量多进步的使用 高风险的弱势群体，（2）检查新型多物质使用评估的预测有效性 通过在高风险脆弱人群中检查六个月内的风险行为，并获得（3）获取工具 有关多进步的干预策略的发展和可接受性的初步数据 人群。根据该奖项的结论，PI将被定位为PolySubstance使用的崛起领导者 研究并在通过未来的R-Menerianc的PolySubstance使用干预措施的职业中表现出色 资金机会。