Development of a novel polysubstance assessment tool for vulnerable subpopulations

为弱势群体开发新型多物质评估工具

• 批准号: 10649443
• 负责人: Amanda M Bunting
• 金额: $ 18.17万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10649443
• 关键词: Address; Assessment tool; Award; Behavior; Communicable Diseases; Community Workers; Complement; Complex; Data; Development; Device or Instrument Development; Environment; Face; Focus Groups; Frequencies; Funding; Funding Mechanisms; Funding Opportunities; Future; General Population; Goals; Health; Health Services; Individual; Injecting drug user; Injections; Intervention; Interview; Investigation; Jail; Justice; Knowledge; Measures; Mentors; Methodology; Methods; Motivation; National Institute of Drug Abuse; New York; Opioid; Outcome; Overdose; Pattern; Persons; Pharmaceutical Preparations; Population; Positioning Attribute; Prevalence; Prisons; Property; Psychometrics; Reporting; Research; Research Personnel; Risk; Risk Assessment; Risk Behaviors; Route; Sampling; Screening procedure; Sociology; Substance Use Disorder; Surveys; Testing; Training; Universities; Validation; Vulnerable Populations; adverse outcome; career; cognitive interview; contingency management; design; follow-up; heroin use; high risk; high risk population; housing instability; improved; informant; instrument; medical schools; mortality; novel; opioid overdose; opioid user; overdose death; overdose risk; polysubstance use; psychological distress; recruit; skills; substance use; therapy development; tool; tool development

PROJECT SUMMARY/ ABSTRACT The purpose of this timely and significant K01 is to provide the PI (Dr. Bunting) with the training and expertise necessary to become an independent investigator of substance use research, specializing in the development of interventions that improve health outcomes of vulnerable populations with a specific focus on polysubstance use involving opioids. Despite the prevalence of polysubstance use and its association with high-risk outcomes such as overdose, significant gaps in our understanding persist in part due to limitations of existing substance use screening and assessment tools. The ability to accurately measure polysubstance use among high-risk populations is a critical step towards developing effective strategies for improving substance-related health outcomes of this population. The overall goal of the proposal is the development of a novel polysubstance assessment tool and identification of correlates and motivations of polysubstance use behaviors among high- risk vulnerable populations. The long-term goal of this line of investigation is to develop interventions targeted to polysubstance use behaviors in vulnerable populations as an independent investigator of substance use research. To achieve this goal, the proposed award has been designed to augment the PI’s existing training in sociology and health services through a comprehensive plan that will enable her to: (1) obtain methodological skills specific to instrument development and validation, (2) enhance her ability to conduct independent research including the recruitment and retention of vulnerable populations and remote study management, and (3) develop focused skills in health services intervention development specific to vulnerable populations (i.e., persons who use substances, justice-involved). These skills will be developed at the high-impact training environment of the New York University Grossman School of Medicine with a collaborative mentoring team of nationally renowned experts. The training plan is strategically complemented by a rigorous mixed-method study. Building on prior training while expanding to new skills, the independent line of research aims to: (1) develop and test the psychometric properties of a novel assessment tool to measure polysubstance use for high-risk vulnerable populations, (2) examine the predictive validity of the novel polysubstance use assessment tool by examining risk behaviors over a 6-month period in a high-risk vulnerable population, and (3) acquire preliminary data regarding the development and acceptability of intervention strategies for polysubstance use populations. By the conclusion of this award, the PI will be positioned as a rising leader in polysubstance use research and positioned to excel in a career of polysubstance use interventions through future R-mechanism funding opportunities.

项目概要/摘要 这个及时而重要的 K01 的目的是为 PI（Bunting 博士）提供培训和专业知识 有必要成为物质使用研究的独立调查员，专门从事开发 改善弱势群体健康结果的干预措施，特别关注多物质 涉及阿片类药物的使用。尽管多种物质的使用很普遍并且与高风险结果相关 例如药物过量，我们的理解仍然存在重大差距，部分原因是现有物质的局限性 使用筛选和评估工具。能够准确测量高风险人群中多种物质的使用情况 人口是制定有效战略以改善与物质相关的健康的关键一步 该人群的结果。该提案的总体目标是开发一种新型多物质 评估工具并识别高危人群多物质使用行为的相关性和动机 给弱势群体带来风险。这一调查的长期目标是制定有针对性的干预措施 作为物质使用的独立调查员，研究弱势群体中的多物质使用行为 研究。为了实现这一目标，拟议的奖项旨在增强 PI 的现有培训 通过一项全面的计划，社会学和卫生服务将使她能够：（1）获得方法论 特定于仪器开发和验证的技能，（2）增强她独立进行的能力 研究包括招募和保留弱势群体以及远程研究管理，以及 (3) 培养针对弱势群体制定卫生服务干预措施的重点技能（即， 使用物质的人，涉及正义）。这些技能将在高影响力的培训中得到发展 纽约大学格罗斯曼医学院的环境以及协作指导团队 国内知名专家。培训计划由严格的混合方法进行战略性补充 学习。以先前的培训为基础，同时扩展新技能，独立的研究方向旨在：(1) 开发并测试一种新型评估工具的心理测量特性，以测量多物质的使用情况 高风险弱势群体，(2) 检查新型多物质使用评估的预测有效性 通过检查高风险弱势群体 6 个月内的风险行为来使用工具，以及 (3) 获取 关于多物质使用干预策略的制定和可接受性的初步数据 人口。该奖项结束后，PI 将被定位为多物质使用领域的新兴领导者 研究并定位于通过未来的 R 机制在多物质使用干预的职业生涯中表现出色 融资机会。