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Northwestern University Clinical and Translational Science Institute (NUCATS)

西北大学临床与转化科学研究所 (NUCATS)

基本信息

批准号：
10434674
负责人：
Susanna A McColley
金额：
$ 35.14万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-08-12 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10434674
关键词：
Address Adolescent Adult Basic Science Brain Neoplasms Child Health Childhood Clinical Clinical Sciences Communication Communities Complement Computers Data Engineering Data Science Data Scientist Discharge Plannings Discipline Doctor of Philosophy Economics Educational Curriculum Elements Engineering Environment Foundations Funding General Anesthesia Goals Health Individual Institutes Leadership Learning Life Cycle Stages Machine Learning Mentors Minority-Serving Institution Modernization Nanotechnology Patient Care Pediatric Research Pediatrics Positioning Attribute Postdoctoral Fellow Research Research Personnel Students TNFSF15 gene Talents Technology Training Training Activity Training Programs Translating Translational Research Underrepresented Minority Universities Work Writing adolescent health bridge program career experience improved innovation interest multidisciplinary novel novel strategies pediatrician peer post-doctoral training pre-doctoral programs summer research tool translational health science

项目摘要

ABSTRACT: The health of children and adolescents is a critical determinant of our nation's health over the entire life course. Yet, research into child health lags behind that for adults. In part, this reflects historical, cultural and economic forces that tend to divert investigators into careers other than pediatric research. To address this concern, the Northwestern University Clinical and Translational Sciences Institute (NUCATS) chose the unique approach of specifically training young investigators to apply engineering solutions to problems in child health. Our overall goal is to generate a community of pediatricians, data scientists and engineers who collaborate across disciplines, using modern technology to improve the health of children and adolescents. The central focus of this continuing and highly successful effort is this Multidisciplinary Training Program in Child and Adolescent Health TL1, which has three specific aims. In Aim 1, we will train 10 postdoctoral fellows in basic science or pediatrics for two years, in a creative and multidisciplinary environment where investigators are equipped to apply innovative engineering approaches to problems in child and adolescent health. The fellows must have a mentor in both pediatrics and engineering. Presently, their projects range from computer-controlled delivery of general anesthesia or using nanotechnology to treat brain tumors, to applying machine learning to optimize discharge planning. This innovative research experience is complemented by mentoring from the TL1 leadership and from their postdoctoral-fellow peers; required foundational elements, which promote communication across traditionally disparate scientific disciplines; required selective components, assigned to individual fellows to optimize their training in pediatric clinical and translational science; and a menu of enrichment opportunities that are optional for each trainee. All of these components include both didactic and experiential approaches. In Aim 2, to expand the pipeline of engineers entering child and adolescent health research, we will provide 2, one-year positions (1 supported by the CTSA and 1 by institutional funds) for predoctoral engineers entering the last year of PhD training, especially those representing underrepresented minorities, as they complete their research and write their thesis. By including engineering trainees who are interested in CTS in the training activities available to our TL1 postdoctoral fellows, we intend to enhance their potential commitment to pediatric translational science. Finally, in Aim 3, we will provide a summer research experience at Northwestern for 4 students in clinical post-baccalaureate programs at a traditionally underrepresented-minority institution. Our experience to date suggests that, with our ongoing involvement after the summer experience, many of these students have been inspired to seek careers in translational research. Together, these aims outline a comprehensive and successful program to increase the number and quality of investigators applying innovative approaches to improving child and adolescent health.

摘要：儿童和青少年的健康状况是决定我国整体健康水平的关键因素