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Strengthening COVID-19 prevention strategies via wastewater surveillance in a Northern Plains Tribe

通过北部平原部落的废水监测加强 COVID-19 预防策略

基本信息

批准号：
10436763
负责人：
Jeffrey A Henderson
金额：
$ 51.67万
依托单位：
BLACK HILLS CTR/AMERICAN INDIAN HEALTH
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-09-01 至 2026-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10436763
关键词：
2019-nCoV Address Affect Alaska Native American Indians Attitude Behavioral Businesses COVID-19 COVID-19 pandemic COVID-19 prevention COVID-19 surveillance Cessation of life Cheyenne Chronic Clinical Data Color Communicable Diseases Communities Coronavirus Detection Diagnostic Reagent Kits Disease Disease Outbreaks Disease Surveillance Emergency response Environmental Impact Environmental Monitoring Epidemic Ethics Ethnic group Future Generations Geographic state Goals Health Housing Incidence Indian reservation Infectious Agent Infrastructure Knowledge Mind Northern Plains Tribe Prevention strategy Process Qualitative Methods Research Research Personnel Reservations Resources Rivers Running Rural Schools Sioux Indians Smallpox South Dakota Spanish flu Speed Surveillance Program System Testing Teton Sioux Indian Thinking Travel Tribes United States United States Indian Health Service Viral Virus density design effectiveness evaluation epidemiologic data experience frontier multidisciplinary northern plains novel coronavirus pandemic disease personal protective equipment programs public health emergency racial and ethnic screening social tribal community tribal leader tribal member wastewater surveillance wastewater testing

项目摘要

Despite the abundance of clinical and epidemiologic data collected during this pandemic, relatively little focus has been paid to the examination of infectious agents through bulk wastewater detection and epidemiological data that is particularly well-suited for disease surveillance in remote, frontier settings such as the CRST Reservation. The goal of this application is to develop and implement a 15-community wastewater testing program for viral contaminants, including SARS-CoV-2, to better understand the utility of wastewater testing and COVID-19 or other viral outbreaks in this remote, low-resourced, and relatively low-density Tribal community. We will use our highly collaborative, multidisciplinary team of Native investigators to develop and implement, and evaluate the effectiveness of a viral wastewater sequencing testing program in a very rural and remote Northern Plains Lakota Reservation. Therefore, we propose to leverage our 20-year, long-running partnership with CRST to address the following Specific Aims: 1. Use a highly participatory approach to design, garner approval for, and implement a wastewater testing system in a large Tribal reservation community. This community surveillance approach will screen for viral isolates, including SARS-CoV-2, in coordination with CRST’s preexisting COVID-19 surveillance system; and 2. Deploy qualitative methods to examine 16 key Tribal stakeholders’ and Tribal members’ attitudes towards this new community wastewater testing approach and, ultimately, how this new environmental testing effort affects Tribal members socially, ethically, and behaviorally; and 3. Seek to codify this new resource into the Tribe’s public health emergency response program, thereby enhancing the Tribe’s capacity for future viral and other likely epidemic and pandemic outbreaks.

尽管在这次大流行期间收集了丰富的临床和流行病学数据，但相对而言