Mentoring and Patient-Oriented Research on Social Exposures and CVD Risk in Underrepresented Women

针对代表性不足的女性的社会暴露和心血管疾病风险的指导和以患者为导向的研究

基本信息

批准号：
10440016
负责人：
Tené T Lewis
金额：
$ 12.38万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-05-01 至 2027-04-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10440016
关键词：
African American Age Animal Model Antral Automobile Driving Award Biological Assay Biological Markers Blood specimen Body mass index Cardiology Cardiovascular Diseases Chronology Collaborations Consultations Data Development Discipline Discrimination Disease Doctor of Philosophy Education Educational workshop Emotional Epidemiology Estrogens Exposure to Family Fellowship Program Female Financial Hardship Follicle Stimulating Hormone Fostering Friends Funding Future Genetic Goals Grant Health Health Services Accessibility Hormones Knowledge Link Master of Public Health Measures Menopause Menstrual cycle Mentors Meta-Analysis Modeling Morbidity - disease rate National Heart, Lung, and Blood Institute Outcome Ovarian Ovarian aging Parents Physiologic pulse Physiological Pilot Projects Play Premature Menopause Premenopause Process Public Health Schools Records Reporting Research Research Personnel Risk Risk Factors Role Science Smoking Socioeconomic Status Study of Women&apos s Health Across the Nation Subgroup System Time Training Training Programs Underrepresented Populations Universities Vulnerable Populations Weather Woman Women&apos s Group Women&apos s Health aged black/white disparity cardiovascular disorder prevention cardiovascular disorder risk cardiovascular health cardiovascular risk factor career cohort design diminished ovarian reserve health inequalities interest intima media medical schools men middle age minority scientist mortality mullerian-inhibiting hormone multidisciplinary multimodality nonhuman primate ovarian reserve patient oriented patient oriented research programs prospective racial and ethnic reproductive reproductive senescence skills social social stress social stressor sociodemographics stress management supportive environment therapy design ultrasound

项目摘要

PROJECT SUMMARY This Mid-Career Investigator Award in Patient-Oriented Research is designed to provide Dr. Tené T. Lewis with protected time and other support to: 1) advance her current program of research, focused on understanding how social stressors contribute to cardiovascular disease (CVD) risk in underrepresented and understudied groups of women; 2) accelerate a successful record of mentoring junior patient-oriented researchers across disciplines, with an emphasis on trainees historically underrepresented in research (e.g. racial/ethnic minority scientists); 3) enhance her mentoring skills, with a particular focus on transdisciplinary approaches and best-practices in providing mentoring and support to underrepresented groups; and 4) obtain training in the examination of biomarkers of ovarian aging, as emerging risk factors for CVD in women. Mentoring activities will leverage Dr. Lewis’ ongoing involvement in several training programs at Emory University, including an NHLBI-funded multidisciplinary T32 training grant on cardiovascular health inequities that she co-directs, the research-track Cardiology fellowship program at the School of Medicine, and the Master of Public Health and PhD programs in Epidemiology at the Rollins School of Public Health. Mentoring training will occur via workshops and regular consultation with senior investigators with established track records in mentoring of patient-oriented researchers from a range of disciplinary and sociodemographic backgrounds. Training in ovarian aging will build upon Dr. Lewis’ existing collaborations at Emory and with the Study of Women’s Health Across the Nation (SWAN). Finally, the science proposed in the award will extend Dr. Lewis’ research in critically important new directions, by examining ovarian aging as a biologically plausible mechanism that might further contribute to our understanding of how social stressors impact subclinical CVD in vulnerable subgroups of women (particularly African-American women) highlighting processes occurring at midlife, when excess rates are most pronounced.

项目摘要这项以患者为导向研究的中期研究员奖旨在为TenéT。Lewis博士提供有受保护的时间和其他支持：1）推进她当前的研究计划，重点关注代表性不足以及社会压力源如何促进代表性不足的心血管疾病（CVD）风险研究的妇女群体； 2）加速了脑力以来以患者为导向的成功记录跨学科的研究人员，重点是研究人员的研究不足（例如，种族/族裔少数民族科学家）； 3）提高她的心理技能，特别关注跨学科在为代表性不足的群体提供心理和支持方面的方法和最佳实践； 4）获得在检查卵巢衰老的生物标志物的培训中，作为女性CVD的新兴风险因素。指导活动将利用刘易斯博士持续参与Emory的多个培训计划大学，包括NHLBI资助的多学科T32心血管健康不平等培训补助金她共同指导，医学院的研究轨道心脏病学研究金计划，罗林斯公共卫生学院的流行病学公共卫生和博士学位硕士。指导培训将通过研讨会和与既定轨道的高级调查员进行定期咨询来自一系列学科和社会人口统计学的患者研究人员的心理记录背景。在卵巢衰老的培训将基于刘易斯博士在埃默里的现有合作以及与研究全国妇女健康（天鹅）。最后，奖项中提出的科学将扩展刘易斯博士在至关重要的新方向上的研究，通过研究卵巢老化为生物学上的合理可能进一步有助于我们对社会压力源如何影响亚临床CVD的机制妇女的弱势亚组（尤其是非裔美国妇女）强调了发生的过程中年，当超过率最明显时。