Research and development of plant-derived nutrient blends

强化食品和食品补充剂可以帮助解决一些关键的健康和环境问题，包括肥胖，营养不良和食物浪费，但是，目前所有的领先品牌都含有合成营养素，目前对合成营养素的了解还不够。越来越多的人依赖合成营养素，这意味着越来越需要了解合成营养素与植物源营养素的健康影响，以便食品制造商更好地做出决策，合成营养素是分离的、实验室制造的类似物，与天然等价物相似但不相同，其分离形式缺乏与植物来源的营养素天然存在的协同化合物和辅因子。现有的研究表明，合成物可能比天然营养素的生物利用度更低，效果更差（例如：_1，Chen，F等人，Association Among Dietary Supplement Use，Nutrient Intake，and Mortality Among U.S.Adults.内科学年鉴。5/2019\.（2_），但目前评估食品中合成营养素和天然营养素在公众食用时对健康影响的研究有限。生物技术和生物技术研究所将研究合成营养素和天然营养素在公众食用时在食品（如营养奶昔）中的生物利用度和有效性方面的差异。对现有天然与合成营养素的研究进行文献综述.规划并进行了试点研究和后续的临床研究.完成中试研究，评估植物源与合成营养素的相对生物利用度和功效.根据项目研究结果，开发新的BIOVIT产品.提高公众对合成与植物来源营养素影响的认识和理解。帮助提供更好的营养选择。

Fortified foods and food supplements could help address a number of key health and environmental issues, including obesity, malnutrition and food waste, however, all current leading brands contain synthetic nutrients, about which not enough is currently known.Increasing reliance on synthetic nutrients presents a growing need to understand the health implications of synthetic vs plant-derived nutrition, to enable better decision making by food manufacturers, health bodies and individuals, with far reaching potential health and environmental benefits.Synthetic nutrients are isolated, lab-made analogues which are similar but not identical to natural equivalents, which in their isolated form, lack the synergistic compounds and cofactors which are naturally present with plant-derived nutrients. Existing studies indicate that synthetics may be less bioavailable and less effective than natural nutrients (for example: _1, Chen, F et al. Association Among Dietary Supplement Use, Nutrient Intake, and Mortality Among U.S. Adults. Annals of Internal Medicine. 5/2019\. 2_), but there is limited research assessing the effects on health of synthetic v natural nutrients incorporated in foods, over time, as they are consumed by the public.BIOVIT will carry out research into the differences between synthetic and natural nutrients, in terms of bioavailability and effectiveness, when consumed as they are by the public, within food, such as nutrition shakes.This project will deliver the following outputs:1. Literature review of existing research on natural v synthetic nutrients.2. Planning and a pilot study and subsequent clinical study.3. Completing a pilot study, assessing relative bioavailability and efficacy of plant-derived vs synthetic nutrients.4. Based on project research findings, development of new BIOVIT products.5. Increased public awareness and understanding of effects of synthetic vs plant-derived nutritions.6. Help enable better nutrition choices.