The National Drug Abuse Clinical Trials Network: New England Consortium Node

摘要 NIDA临床试验网络的管理补充：新英格兰联盟 Node支持三个具体概念： 1)按种族和性别分类的CTN治疗结局的综合荟萃分析 该项目将进行额外的荟萃分析，检查种族和性别是否/如何 相互作用，以预测治疗成功的可能性和随机分组的可能性。 CTN试验与筛选失败。将进行探索性分析，评估这些 结果因种族而异（即西班牙裔/拉丁裔）。 2)使用综合数据分析来检查心理社会的影响 入组CTN的黑人患者的治疗 利用多个CTN试验的综合数据分析，本项目将检查 物质使用障碍治疗的比较有效性和调节剂， 黑人吸毒者 3)NIDA CTN物质使用障碍（SUD）登记倡议概念 该项目将建立一个NIDA CTN物质使用障碍登记处， 调查人员将跟踪物质使用者一段时间。

ABSTRACT This Administrative Supplement to the NIDA Clinical Trials Network: New England Consortium Node is to support three specific concepts: 1) Comprehensive Meta-Analysis of CTN Treatment Outcomes by Race and Sex This project will perform additional meta-analyses examining whether/how race and sex interact to predict likelihood of treatment success and likelihood of randomization into a CTN trial versus screen fail. Exploratory analysis will be conducted evaluating how these outcomes vary by ethnicity (i.e. Hispanic/Latinx). 2) Using Integrative Data Analysis to Examine the Impact of Psychosocial Treatments for Black Cocaine Users Enrolled in the CTN Using integrative data analysis of multiple CTN trials, this project will examine comparative effectiveness and moderators of substance use disorder treatments for Black substance users. 3) NIDA CTN Substance Use Disorder (SUD) Registry Initiative concept This project will establish a NIDA CTN Substance Use Disorder Registry to allow investigators to follow substance users over time.