The National Drug Abuse Clinical Trials Network: New England Consortium Node
国家药物滥用临床试验网络:新英格兰联盟节点
基本信息
- 批准号:10450554
- 负责人:
- 金额:$ 170万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-03-01 至 2022-02-28
- 项目状态:已结题
- 来源:
- 关键词:Accident and Emergency departmentBuprenorphineCase SeriesClinicalClinical Trials NetworkDrug abuseElectronic Health RecordEligibility DeterminationEmergency Department patientEmergency department visitNew EnglandOpioidPatientsPhenotypeRandomized Controlled TrialsResourcesSiteTrainingWithdrawal Symptomaddictioncompare effectivenessdesignimplementation facilitationopioid use disorderopioid withdrawalpatient engagementprescription opioidprimary outcomerecruit
项目摘要
ABSTRACT
This study will (1) recruit, train and provide resources to approximately 30 Emergency Department (ED) sites
throughout the U.S. using implementation facilitation strategies to provide ED-initiated BUP for patients
presenting with opioid use disorder (OUD) not receiving medications for opioid use disorder (MOUD). Once
implementation is adequately achieved, the sites will (2) conduct a randomized controlled trial (RCT) to
compare the effectiveness of sublingual buprenorphine (SL-BUP) versus extended-release buprenorphine
(XR-BUP) on ED patients’ engagement in formal addiction treatment 7-days after their ED visit. In addition, in
an ancillary component of the study, we will (3) assess the use of XR-BUP in ED patients with Clinical Opioid
Withdrawal Scale (COS) scores < 8 in a case series to potentially expand the eligibility of patients in the larger
RCT to those presenting with little to no opioid withdrawal symptoms. Finally, we will (4) develop and validate
ED electronic health record (HER) opioid-related phenotypes, both of which will inform the main RCT.
摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Gail D'Onofrio其他文献
Gail D'Onofrio的其他文献
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{{ truncateString('Gail D'Onofrio', 18)}}的其他基金
Yale-METRO Metropolitan Emergency Trial netwoRK to advance patient Outcomes
耶鲁大学-METRO 大都会紧急试验网络可改善患者的治疗效果
- 批准号:
10552382 - 财政年份:2023
- 资助金额:
$ 170万 - 项目类别:
Clinical Trials Network: Admin Supplement: Integrating MOUD with BUP in Non-medical Community Settings
临床试验网络:管理补充:在非医疗社区环境中将 MOUD 与 BUP 集成
- 批准号:
10801347 - 财政年份:2023
- 资助金额:
$ 170万 - 项目类别:
Standard versus High Dose ED-Initiated Buprenorphine Induction
标准剂量与高剂量 ED 引发的丁丙诺啡诱导
- 批准号:
10801950 - 财政年份:2023
- 资助金额:
$ 170万 - 项目类别:
Clinical Trials Network New England Consortium Node: Admin Supplement CTN0131
临床试验网络新英格兰联盟节点:管理补充 CTN0131
- 批准号:
10655837 - 财政年份:2022
- 资助金额:
$ 170万 - 项目类别:
National Institute on Drug Abuse Clinical Trial Network: New England Consortium Node
国家药物滥用研究所临床试验网络:新英格兰联盟节点
- 批准号:
10684501 - 财政年份:2022
- 资助金额:
$ 170万 - 项目类别:
Clinical Trials Network New England Consortium Node: Admin Supplement CTN0126
临床试验网络新英格兰联盟节点:管理补充 CTN0126
- 批准号:
10655828 - 财政年份:2022
- 资助金额:
$ 170万 - 项目类别:
The National Drug Abuse Clinical Trials Network: New England Consortium Node
国家药物滥用临床试验网络:新英格兰联盟节点
- 批准号:
10442107 - 财政年份:2021
- 资助金额:
$ 170万 - 项目类别:
The National Drug Abuse Clinical Trials Network: New England Consortium Node
国家药物滥用临床试验网络:新英格兰联盟节点
- 批准号:
10451986 - 财政年份:2021
- 资助金额:
$ 170万 - 项目类别:
EMBED: Pragmatic trial of user-centered clinical decision support to implement EMergency department-initiated BuprenorphinE for opioid use Disorder
EMBED:以用户为中心的临床决策支持的实用试验,以实施急诊部门发起的丁丙诺啡E治疗阿片类药物使用障碍
- 批准号:
9928151 - 财政年份:2018
- 资助金额:
$ 170万 - 项目类别:
EMBED: Pragmatic trial of user-centered clinical decision support to implement EMergency department-initiated BuprenorphinE for opioid use Disorder
EMBED:以用户为中心的临床决策支持的实用试验,以实施急诊部门发起的丁丙诺啡E治疗阿片类药物使用障碍
- 批准号:
10379284 - 财政年份:2018
- 资助金额:
$ 170万 - 项目类别:
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