Core A: Administrative Core

核心A：行政核心 总结/摘要 行政核心将负责行政、财政、组织和通信。 这是一个庞大、复杂和高度互动的项目。为了确保U19的成功，该计划已 由华盛顿大学的首席研究员丹尼尔·普罗米斯洛博士和 德克萨斯A&M大学兽医学院的首席兽医官Kate Creevy博士 和生物医学科学Promislow博士和Creevy博士已经密切合作了九年。博士 Creevy将担任Core C的总监和项目1的负责人。除了Creevy博士和Levine博士（也在 TAMU），所有其他科学参与者都隶属于华盛顿大学，确保了访问的便利性 以及核心和项目之间顺畅的沟通渠道。作为U19的核心A和PI总监 Promislow博士将担任NIH的主要联系人，并将监督所有财务互动 和分包合同，在合作研究者马特·凯伯莱因博士的协助下。Promislow博士和Dr. Creevy将得到当地行政支持的协助，以促进 研究人员、核心和项目。行政核心的总体目标是：1）提供领导， 指导和有效的组织结构，促进核心和项目之间的沟通 并确保我们的科学目标的质量和进展; 2）与数据和分析核心B合作， 确保遵守最高标准的研究设计和分析; 3）管理财政监督 整个计划项目;和4）提供短期和长期规划。

CORE A: ADMINISTRATIVE CORE SUMMARY/ABSTRACT The Administrative Core will be responsible for the administrative, fiscal, organizational and communication needs of this large, complex and highly interactive program. To ensure success of this U19, the Program has been established with a Principal Investigator, Dr. Daniel Promislow, at the University of Washington, and a Chief Veterinary Officer, Dr. Kate Creevy, at Texas A&M University's (TAMU) College of Veterinary Medicine and Biomedical Sciences. Dr. Promislow and Dr. Creevy have been close collaborators for nine years. Dr. Creevy will be the Director of Core C and Leader of Project 1. Other than Dr. Creevy and Dr. Levine (also at TAMU), all other scientific participants are affiliated with the University of Washington, ensuring ease of access and smooth lines of communication among Cores and Projects. As Director of Core A and PI of the U19 Program Project, Dr. Promislow will serve as the NIH primary contact and will oversee all financial interactions and sub-contracts, with assistance from co-Investigator Dr. Matt Kaeberlein. Both Dr. Promislow and Dr. Creevy will be assisted by local administrative support to facilitate the lines of communication between the Investigators, Cores and Projects. The overall goals of the Administrative Core are to 1) provide leadership, guidance, and effective organizational structure that promotes communication between Cores and Projects and ensures the quality and progress of our scientific goals; 2) work with the Data and Analysis Core B to ensure adherence to the highest standards of research design and analysis; 3) manage fiscal oversight of the entire Program Project; and 4) provide short- and long-range planning.