STROKENET REGIONAL COORDINATING CENTER Georgia StrokeNet

STROKENET 区域协调中心 佐治亚州 StrokeNet

• 批准号: 10457481
• 负责人: MICHAEL Ross FRANKEL
• 金额: $ 30.47万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-01 至 2023-12-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10457481
• 关键词: Accident and Emergency department; Acute; Agreement; Caring; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Network; Collaborations; Communities; Data; Detection; Discipline; Disease; Early treatment; Emergency Care; Emergency Medicine; Enrollment; Evidence based practice; Funding; Goals; Hospitals; Hour; Individual; Industry; Infrastructure; Institutes; Institutional Review Boards; Intervention; Interview; Investigation; Joints; Leadership; Link; Master of Public Health; Master of Science; Medical; Medicine; Methods; Mission; Multi-Institutional Clinical Trial; National Institute of Neurological Disorders and Stroke; Neurologic; Neurological emergencies; Neurology; Neurosciences Research; Outreach Research; Patients; Pediatrics; Peer Review; Persons; Pharmacy Ethics; Protocols documentation; Public Health; Randomized Clinical Trials; Recording of previous events; Recovery; Recurrence; Registries; Rehabilitation therapy; Research; Research Assistant; Research Personnel; Research Subject Recruitments; Research Subjects; Research Training; Resources; Risk; Scientist; Site; Source; Stroke; Stroke prevention; StrokeNet clinical trials; StrokeNet trials; System; Translating; Translational Research; United States National Institutes of Health; Work; acute stroke; base; career; clinical practice; data management; data sharing; design; effective therapy; evidence base; experience; faculty mentor; improved; innovation; interest; member; neurosurgery; participant enrollment; patient registry; patient screening; pre-clinical; programs; recruit; screening; skills; stroke clinical trials; stroke rehabilitation; success; synergism; telestroke; training opportunity; treatment trial; working group

The Specific Aims of this proposal are to: : 1) enhance the successful mission of the Georgia StrokeNet by accelerating recruitment into NIH StrokeNet clinical trials for patients with acute stroke, people at risk for recurrent stroke and individuals recovering from stroke; 2) develop and propose new and innovative clinical trials in stroke to be conducted within the NIH StrokeNet; and 3) enhance the training opportunities for promising young investigators interested in clinical stroke research as a career. As a currently-funded NIH StrokeNet Regional Coordinating Center (RCC), the Georgia StrokeNet brings an established infrastructure of highly successful and collaborative investigators and coordinators, with many years of proven expertise in designing, conducting, and enrolling patients into randomized clinical trials across the continuum of stroke care, from pre-hospital through rehabilitation. Our RCC has demonstrated the ability to quickly implement research protocols using master trial agreements and a central IRB, and has brought to the existing network strong leadership skills, as evidenced by our team members’ active and ongoing participation in NIH StrokeNet working groups including Co-Chair of the NIH StrokeNet’s Rehabilitation working group and the only Project Coordinator representation in the Acute Stroke Working Group since implementation. Emory’s Georgia StrokeNet proposal builds upon our RCC’s track record of 5 years of highly successful participation as an NIH StrokeNet site, 10 years as a top enroller for the NINDS-sponsored Neurological Treatment Trials Network (NETT), recent selection as one of only 11 hubs for the NIH-funded SIREN (Strategies to Innovate EmeRgENcy Care) Clinical Trials Network, and a 25 year history of high enrollment in multiple NIH and industry sponsored practice changing randomized clinical trials in stroke.

本提案的具体目标是：1）通过以下方式加强格鲁吉亚StrokeNet的成功使命 加速招募急性卒中患者和高危人群进入NIH StrokeNet临床试验 对于复发性中风和中风恢复的个人; 2）开发和提出新的和创新的 在NIH StrokeNet内进行中风临床试验; 3）加强培训 有前途的年轻研究人员有兴趣在临床中风研究作为一个职业的机会。 作为目前资助的NIH StrokeNet区域协调中心（RCC），格鲁吉亚StrokeNet带来了 多年来，建立了非常成功和协作的调查员和协调员的基础设施 在设计、实施和招募患者参加随机临床试验方面， 中风护理的连续性，从院前到康复。我们的RCC已经证明有能力 使用主试验协议和中央IRB快速实施研究方案，并使 现有的网络强大的领导能力，我们的团队成员的积极和持续的参与证明 NIH StrokeNet工作组，包括NIH StrokeNet康复工作组的联合主席， 自实施以来，急性卒中工作组中唯一的项目协调员代表。埃默里的 格鲁吉亚StrokeNet提案建立在我们RCC 5年来非常成功的参与记录之上， 一个NIH StrokeNet网站，10年来一直是NINDS赞助的神经治疗试验的最佳注册者 网络（NETT），最近被选为NIH资助的SIREN（创新战略）仅有的11个中心之一 EmeRgENcy Care）临床试验网络，以及25年来在多个NIH和行业的高招募历史 赞助的实践改变了中风的随机临床试验。