The Development of Eating Behavior in Infancy: Associations with Behavior, Diet, and Growth to Age 6 years

婴儿期饮食行为的发展：与行为、饮食和 6 岁生长的关联

• 批准号: 10457444
• 负责人: Julie C Lumeng
• 金额: $ 61.98万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10457444
• 关键词: 5 year old; 6 year old; Address; Adult; Affect; Age; Area; Attention; Behavior; Behavioral; Body mass index; Characteristics; Child; Child Development; Childhood; Coercion; Cohort Studies; Data Collection; Desire for food; Development; Diet; Dimensions; Eating Behavior; Exposure to; Food; Funding; Future; Growth; Health; Individual; Infant; Informal Social Control; Intervention; Literature; Measures; Modeling; Nature; Outcome; Parents; Phenotype; Predictive Value; Predisposition; Protocols documentation; Public Health; Publishing; Reporting; Resources; Stimulus; Structure; Temperament; Testing; Time; United Kingdom; Weight Gain; Work; base; behavior measurement; behavioral phenotyping; cohort; dietary; early childhood; feeding; follow-up; food avoidance; high body mass index; infancy; infant temperament; intervention effect; novel; obesity risk; prospective; response; sucking; therapy development; trait

PROJECT SUMMARY Eating behaviors are robustly associated with dietary quality and weight gain. Given the relevance of eating behaviors to health in children and adults, remarkably little is known regarding the development of these behaviors from infancy, and their continuity (or discontinuity) into childhood. Eating behaviors can be phenotyped in infancy through rigorous measurement of behavior following exposure to different stimuli under careful experimental control, though no studies prior to R01HD084163 have phenotyped multiple eating behaviors objectively in a single longitudinal infant cohort. Eating behavior may be modifiable between infancy and early childhood, potentially altering any associations with future dietary quality or weight gain. Interventions that promote adaptive maternal feeding practices have been effective in reducing obesity risk. Intervention effects might be further strengthened by tailoring to characteristics of the individual child. Identifying interactions of carefully phenotyped child eating behavior and maternal feeding practices in an observational cohort study is an important initial step towards future tailored intervention development. The proposed work will examine for the first time the continuity (or discontinuity) of extensively phenotyped eating behaviors in infancy, based on novel objective measures and maternal report, to age 5 years. The work will, for the first time, test whether maternal feeding practices and infant eating behaviors interact to predict child eating behaviors at age 5 years, as well as dietary quality and BMI at age 6 years. The ABC Baby study (R01HD084163, 7/1/15-06/30/20) and its ancillary funded studies used novel behavioral protocols to phenotype eating behavior and maternal feeding practices longitudinally at ages 2 weeks, and 2, 4, 6, 9, and 12 months in a cohort of 286 infants. The current application proposes to follow up with 200 of these children at ages 5 and 6 years to address the following aims: Aim 1: To test the cross-lagged associations between child eating behaviors and maternal feeding practices across infancy and age 5 years. We hypothesize that child eating behaviors in infancy predict child eating behaviors at age 5 years, maternal feeding practices in infancy predict maternal feeding practices at age 5 years, child eating behaviors in infancy predict maternal feeding practices at 5 years, and maternal feeding practices in infancy predict child eating behaviors at 5 years. Aim 2: To test the hypothesis that eating behaviors measured in infancy have direct and indirect (through eating behaviors at age 5 years) associations with dietary quality and BMI at age 6 years. Aim 3: To test the hypotheses that maternal feeding practices in infancy moderate associations of infant eating behaviors with eating behaviors at 5 years, and that maternal feeding practices at 5 years moderate associations of eating behaviors in infancy with dietary quality and BMI at age 6 years, and moderate associations of eating behaviors at age 5 years with dietary quality and BMI at age 6 years.

项目摘要 饮食行为与饮食质量和体重增加牢固相关。鉴于饮食的相关性 儿童和成人健康的行为，关于这些的发展知之甚少 婴儿期的行为及其连续性（或不连续性）到童年。饮食行为可能是 暴露于不同刺激后的行为，在婴儿期表现出婴儿期 仔细的实验​​对照，尽管在R01HD084163之前没有研究表现出多种饮食 在单个纵向婴儿队列中客观地行为。饮食行为可能在婴儿期之间进行修改 和幼儿期，可能会改变与未来饮食质量或体重增加的任何关联。干预措施 促进适应性产妇的喂养实践可有效降低肥胖风险。干涉 通过针对单个孩子的特征量身定制，可以进一步增强效果。识别 观察性的精心表型儿童饮食行为和孕产妇喂养实践的相互作用 队列研究是朝着未来量身定制的干预开发发展的重要第一步。拟议的工作 将首次检查广泛表型饮食行为的连续性（或不连续性） 婴儿期基于新的客观措施和产妇报告，至5岁。这项工作将是第一个 时间，测试产妇喂养习惯和婴儿饮食行为是否相互作用以预测儿童饮食 5岁的行为以及6岁的饮食质量和BMI。 ABC婴儿研究 （R01HD084163，7/1/1/15-06/30/20）及其辅助资助的研究使用了新的行为方案 表型进食行为和孕产妇喂养实践在2周和2、4、6、9岁时纵向 在286名婴儿的队列中12个月。当前的申请建议跟进这些孩子中的200个孩子 5岁和6岁以解决以下目标：目标1：测试儿童之间的跨滞后关联 在婴儿期和5岁之间的饮食行为和孕产妇喂养做法。我们假设那个孩子 婴儿期的饮食行为可以预测5岁年龄段儿童饮食行为，婴儿期产妇喂养习惯 预测5岁的产妇喂养实践，婴儿期儿童饮食行为预测母亲喂养 5年的实践和婴儿期的产妇喂养实践预测了5年的儿童饮食行为。目标2： 测试以下假设，即婴儿期测得的饮食行为具有直接和间接（通过饮食 5岁的行为）与饮食质量和BMI的关联6岁。目标3：测试 假设婴儿饮食行为中等相关的孕产妇喂养实践与 5年的饮食行为，以及在5年中饮食中的孕产妇喂养做法 饮食质量和BMI在6岁时的婴儿期和BMI的行为，饮食中等关联 饮食质量和6岁的BMI在5岁之间的行为。