Core F: Biostatistics and Bioinformatics

核心F：生物统计学和生物信息学

• 批准号: 10457631
• 负责人: Robert H Lyles
• 金额: $ 64.25万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10457631
• 关键词: Acquired Immunodeficiency Syndrome; Advocate; Applications Grants; Area; Award; Behavioral; Bioinformatics; Biometry; Case Report Form; Clinical; Clinical Research; Collaborations; Consultations; Data; Data Analytics; Development; Doctor of Philosophy; Ensure; Epidemic; Faculty; Fostering; Funding; Future; Goals; Grant; HIV; Infectious Diseases Research; Leadership; Link; Mentorship; Methodology; Mission; Modernization; Participant; Positioning Attribute; Publications; Registries; Research; Research Design; Research Methodology; Research Personnel; Role; Science; Seeds; Services; Statistical Methods; System; Talents; Time; Training; Universities; base; career development; database design; design; epidemiology study; innovation; member; next generation; programs; ranpirnase; recruit; social; sound; success; synergism; working group

PROJECT SUMMARY/ABSTRACT The Biostatistics and Bioinformatics (Bios) Core (Core F) provides CFAR Members with access to a highly qualified team of faculty and staff (core members) who are expert key players in team-based science. The goals for populating and deploying this team are to respond to the traditional biostatistical and bioinformatic service needs of CFAR Members, while maintaining capacity for innovation in terms of developing and employing cutting edge methodology toward statistical design and analytic challenges that arise in modern clinical, basic, translational, and social and behavioral epidemiologic research. The Bios Core enhances the impact and rigor of HIV-related research conducted by CFAR Members through collaboration and consultation, as well as through training and mentorship activities that emphasize the career development of new investigators. An innovative Bios Core Liaison system, implemented in 2016, has matured over the current funding period to facilitate the linking of targeted Bios Core faculty members with all science Cores and Scientific Working Group members. The Core offers a complete suite of services that provide support for proposal development, study design, data analytic plans, case report form and database design, and the publication of scientific research. In the next project period, the Bios Core will continue to prioritize emerging HIV researchers through its collaborations with the Developmental Core's pilot grant programs and with the Clinical Research Core to support proposal development and effective use of registry-based data. At the same time, we will foster and strengthen long-term collaborations with established CFAR Members to promote innovative and impactful team science. The Bios Core will focus its activities on the following Specific Aims: Aim 1: Deliver high quality collaborative support to CFAR Members, with particular emphasis on supporting and enhancing the proposals of early-stage HIV investigators; Aim 2: Leverage Core members' specialized expertise in support of the Emory CFAR's overall mission, to develop long-term and self-sustaining scientific collaborations in transdisciplinary research; Aim 3: Enhance both inter- and intra-CFAR synergy through engagement activities designed to promote and disseminate innovative and impactful HIV-related research methods and practice; Aim 4: Promote the next generation of Bios faculty to Core leadership positions and engage talented trainees to ensure the Core's continued long-term success in enhancing CFAR Members' research through sound and cutting edge biostatistical and bioinformatics methodology.

项目摘要/摘要 生物统计学和生物信息学（BIOS）核心（核心F）为CFAR成员提供了高度访问 合格的教职员工团队（核心成员）是基于团队科学的专家主要参与者。这 填充和部署该团队的目标是应对传统的生物统计学和生物信息 CFAR成员的服务需求，同时在开发和 采用尖端方法来实现统计设计和现代出现的分析挑战 临床，基本，转化以及社会和行为流行病学研究。 BIOS核心增强了 CFAR成员通过协作和咨询进行的HIV相关研究的影响和严格 以及通过强调新的职业发展的培训和指导活动 调查人员。 2016年实施的创新的Bios核心联络系统已经成熟 资助期，以促进有针对性的BIOS核心教师与所有科学核心的联系 科学工作组成员。核心提供了一套完整的服务，为 提案开发，研究设计，数据分析计划，案例报告表和数据库设计以及 科学研究的出版。在下一个项目期间，BIOS核心将继续优先考虑新兴 艾滋病毒研究人员通过与发展核心的试点赠款计划的合作以及与 临床研究核心，以支持提案开发和有效使用基于注册表的数据。同样 时间，我们将培养和加强与已建立的CFAR成员的长期合作以促进 创新且有影响力的团队科学。 BIOS核心将将其活动集中在以下特定目标上： 目标1：向CFAR成员提供高质量的协作支持，特别强调支持 并加强早期艾滋病毒研究者的建议； 目标2：利用核心成员的专业专业知识来支持Emory CFAR的整体使命， 在跨学科研究中发展长期和自我维持的科学合作； 目标3：通过旨在促进和 传播与HIV相关的创新和有影响力的研究方法和实践； 目标4：促进下一代BIOS教师以核心领导职务并参与才华横溢的学员 为了确保核心在通过声音和 尖端生物统计和生物信息学方法。