Core F: Biostatistics and Bioinformatics

核心F：生物统计学和生物信息学

• 批准号: 10839607
• 负责人: Robert H Lyles
• 金额: $ 28.48万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10839607
• 关键词: Core; Biostatistics; Bioinformatics

PROJECT SUMMARY/ABSTRACT The Biostatistics and Bioinformatics (Bios) Core (Core F) provides CFAR Members with access to a highly qualified team of faculty and staff (core members) who are expert key players in team-based science. The goals for populating and deploying this team are to respond to the traditional biostatistical and bioinformatic service needs of CFAR Members, while maintaining capacity for innovation in terms of developing and employing cutting edge methodology toward statistical design and analytic challenges that arise in modern clinical, basic, translational, and social and behavioral epidemiologic research. The Bios Core enhances the impact and rigor of HIV-related research conducted by CFAR Members through collaboration and consultation, as well as through training and mentorship activities that emphasize the career development of new investigators. An innovative Bios Core Liaison system, implemented in 2016, has matured over the current funding period to facilitate the linking of targeted Bios Core faculty members with all science Cores and Scientific Working Group members. The Core offers a complete suite of services that provide support for proposal development, study design, data analytic plans, case report form and database design, and the publication of scientific research. In the next project period, the Bios Core will continue to prioritize emerging HIV researchers through its collaborations with the Developmental Core’s pilot grant programs and with the Clinical Research Core to support proposal development and effective use of registry-based data. At the same time, we will foster and strengthen long-term collaborations with established CFAR Members to promote innovative and impactful team science. The Bios Core will focus its activities on the following Specific Aims: Aim 1: Deliver high quality collaborative support to CFAR Members, with particular emphasis on supporting and enhancing the proposals of early-stage HIV investigators; Aim 2: Leverage Core members’ specialized expertise in support of the Emory CFAR’s overall mission, to develop long-term and self-sustaining scientific collaborations in transdisciplinary research; Aim 3: Enhance both inter- and intra-CFAR synergy through engagement activities designed to promote and disseminate innovative and impactful HIV-related research methods and practice; Aim 4: Promote the next generation of Bios faculty to Core leadership positions and engage talented trainees to ensure the Core’s continued long-term success in enhancing CFAR Members’ research through sound and cutting edge biostatistical and bioinformatics methodology.

项目总结/摘要 生物统计学和生物信息学（Bios）核心（核心F）为CFAR成员提供了一个高度 合格的教师和工作人员（核心成员）团队，他们是团队科学的专家关键人物。的 组建和部署该团队的目标是响应传统的生物统计学和生物信息学 满足CFAR成员的服务需求，同时保持发展和 采用尖端的方法对统计设计和分析的挑战，出现在现代 临床、基础、转化以及社会和行为流行病学研究。Bios核心增强了 CFAR成员通过合作和协商进行的艾滋病毒相关研究的影响和严谨性， 以及通过培训和辅导活动，强调新的职业发展， investigators.创新的Bios核心联络系统于2016年实施，目前已经成熟 资助期，以促进目标生物核心教师与所有科学核心的联系， 科学工作组成员。核心提供一整套服务， 方案制定、研究设计、数据分析计划、病例报告表和数据库设计，以及 科学研究的出版。在下一个项目期间，Bios Core将继续优先考虑新兴的 艾滋病毒研究人员通过与发展核心的试点赠款计划和 临床研究核心支持提案制定和有效使用基于注册的数据。在同一 同时，我们将促进和加强与CFAR成员的长期合作， 创新和有影响力的团队科学。Bios核心将把活动重点放在以下具体目标上： 目标1：向CFAR成员提供高质量的协作支持，特别强调支持 加强艾滋病早期调查人员的建议; 目标2：利用核心成员的专业知识支持埃默里CFAR的整体使命， 在跨学科研究中发展长期和自我维持的科学合作; 目标3：通过旨在促进和 传播创新和有影响力的艾滋病毒相关研究方法和实践; 目标4：将下一代Bios教师提升到核心领导岗位，并吸引有才华的学员 以确保核心的持续长期的成功，加强CFAR成员的研究， 尖端的生物统计学和生物信息学方法。