SPINE-WORK: An inclusive research community to study and improve force-based manipulations for spine pain

SPINE-WORK：一个包容性研究社区，致力于研究和改进基于力量的脊柱疼痛治疗方法

• 批准号: 10458296
• 负责人: VICTOR H BAROCAS
• 金额: $ 65.68万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-20 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10458296
• 关键词: Address; Advisory Committees; Affect; Anatomy; Animal Model; Animals; Archives; Area; Award; Biological Markers; Biomechanics; Calendar; Clinic; Clinical; Clinical Sciences; Communication; Communities; Complementary therapies; Computer Models; Confusion; Consultations; Data; Development; Discipline; Education; Educational Activities; Educational workshop; Engineering; Ensure; Event; Experimental Models; Fertilization; Focus Groups; Fostering; Goals; Grant; Health; Image; Infrastructure; Institution; Interdisciplinary Communication; Interdisciplinary Study; Intervention; Journals; Language; Learning; Low Back Pain; Manuscripts; Mission; Molecular; Musculoskeletal; Nature; Neck Pain; Neuromechanics; Neurosciences; Outcome; Pain; Pain Disorder; Pain management; Paper; Pathway interactions; Persons; Pharmaceutical Preparations; Physical therapy; Physics; Physiological; Physiology; Population; Process; Protocols documentation; Publishing; Quality of life; Reporting; Research; Research Personnel; Research Project Grants; Resources; Review Committee; Role; Scientist; Seeds; Spinal Manipulation; Spine pain; Terminology; Testing; Vertebral column; Vocabulary; Work; base; chronic pain; diagnostic biomarker; diversity and inclusion; effective therapy; health equity; improved; in vitro Model; innovation; insight; interest; knowledge base; lens; meetings; member; multidisciplinary; non-opioid analgesic; opioid epidemic; organizational structure; outreach; pain relief; productivity loss; programs; relating to nervous system; support network; symposium; tool; virtual; web site; working group

Low back and neck pain, which impose major impediments to quality of life and are responsible for significant productivity loss, are often treated with expensive, sometimes ineffective, and potentially addictive drugs. Complementary therapies, especially force-based manipulations (FBMs), have the potential to address these challenges but remain poorly understood especially for spine pain. The highly multifaceted nature of FBMs complicates a complete understanding of the physiologic mechanisms involved with pain relief, requiring the integrative synthesis of neuroscience, physics, engineering, physiology, and clinical fields. To address this need, we will create a network - SPINEWORK - of researchers from all disciplines interested in exploring the potential role of FBMs in alleviating spine pain. The network will provide members with the opportunity to identify new collaborators, to learn about other disciplines, to disseminate ideas and information to their colleagues and the larger community, and to foster better interdisciplinary communication. SPINEWORK will support the network of researchers and activities administered by a set of Committees and will be organized into intersecting and evolving Working Groups, each made up of members from multiple institutions and traditional disciplines and focused on specific areas, such as Imaging or Animal Models. The Working Groups will promote interdisciplinary research through physical and virtual gatherings, white papers, journal special issues, and video content. A special Working Group on Terminology will focus on defining a common lexicon for spine pain and forced-based manipulations; this task is essential because even simple terms can have very different meaning to different communities, leading to confusion and impeding progress for collaborative teams. SPINEWORK will sponsor a pilot and facilitation grant program for interdisciplinary collaborative teams formed by its members. The grants will be focused on opportunities to seed or boost R01 proposals, activities that build intellectual infrastructure (e.g., think tanks or workshops), and opportunities for scientists from one discipline immerse in disciplines outside their core area. Annually, SPINEWORK will bring its members together for a Summit meeting to assess its activities, report findings, spawn new Working Groups, review progress, and plan for the coming year. Overall, SPINEWORK's mission is to lay the intellectual groundwork for improved treatment of low back and neck pain via FBMs by creating and fostering a multidisciplinary, scientifically and culturally diverse network of researchers from across the spectrum of approaches to understand FBMs and spine pain.

腰背和颈部疼痛，对生活质量造成重大障碍，并且是造成这种疼痛的原因 对于严重的生产力损失，通常采用昂贵且有时无效的治疗方法 潜在的成瘾药物。补充疗法，尤其是基于力量的操作 （FBM），有潜力解决这些挑战，但仍然知之甚少，尤其是 用于脊椎疼痛。 FBM 的高度多面性使全面理解变得复杂 涉及缓解疼痛的生理机制，需要综合合成 神经科学、物理学、工程学、生理学和临床领域。为了满足这一需求，我们将 创建一个网络 - SPINEWORK - 由来自所有学科、有兴趣探索该领域的研究人员组成 FBM 在缓解脊柱疼痛方面的潜在作用。该网络将为会员提供 识别新合作者、了解其他学科、传播想法的机会 向同事和更大的社区提供信息，并促进更好的 跨学科交流。 SPINEWORK 将支持研究人员网络和 由一组委员会管理的活动将被组织成交叉和 不断发展的工作组，每个工作组由来自多个机构和传统组织的成员组成 学科并专注于特定领域，例如成像或动物模型。工作中 团体将通过实体和虚拟聚会促进跨学科研究，白人 论文、期刊特刊和视频内容。术语特别工作组将 专注于定义脊柱疼痛和强迫性操作的通用词汇；这个任务是 至关重要，因为即使是简单的术语对于不同的社区也可能具有截然不同的含义， 导致混乱并阻碍协作团队的进展。 SPINEWORK 将赞助 为由其组成的跨学科合作团队提供试点和便利补助金计划 成员。赠款将重点用于种子或促进 R01 提案、活动的机会 建立知识基础设施（例如智囊团或研讨会）以及机会 来自某一学科的科学家沉浸在其核心领域之外的学科中。每年， 报告称，SPINEWORK 将召集其成员召开峰会，以评估其活动 调查结果，组建新的工作组，审查进展情况，并为来年制定计划。全面的， SPINEWORK 的使命是为改善腰背治疗奠定知识基础 通过创建和培养多学科、科学和文化的方法，通过 FBM 来治疗颈部疼痛 来自各种不同方法的研究人员网络来理解 FBM 和脊椎疼痛。