SPINE-WORK: An inclusive research community to study and improve force-based manipulations for spine pain

腰背和颈部疼痛，这是生活质量的主要障碍， 对于显著的生产力损失，通常采用昂贵的、有时无效的和 可能会上瘾的毒品。辅助性疗法，特别是基于力的手法 (FBMS)，具有应对这些挑战的潜力，但尤其是仍然知之甚少 治疗脊椎疼痛。FBMS的高度多面性使完全理解变得复杂 与止痛有关的生理机制，需要综合合成 神经科学、物理学、工程学、生理学和临床领域。为了满足这一需求，我们将 创建一个由所有学科的研究人员组成的网络-SPINEWORK，这些研究人员对探索 FBMS在缓解脊柱疼痛方面的潜在作用。该网络将为成员提供 有机会发现新的合作者，了解其他学科，传播思想 并向他们的同事和更大的社区提供信息，并促进更好地 跨学科交流。SPINEWORK将支持研究人员网络和 活动由一系列委员会管理，并将组织成交叉和 不断演变的工作组，每个工作组由来自多个机构和传统的 并专注于特定领域，如成像或动物模型。在工作中 团体将通过物理和虚拟聚会促进跨学科研究，怀特 论文、期刊特刊和视频内容。一个专门的术语工作组将 重点是为脊椎疼痛和基于强迫的操作定义一个通用词典；这项任务是 至关重要，因为即使是简单的术语对不同的社区来说也可能有非常不同的含义， 这会给协作团队带来混乱，阻碍进度。SPINEWORK将赞助一项 为ITS组建的跨学科协作团队提供试点和促进资助计划 会员。赠款将集中在资助或促进R01提案、活动的机会上 建设智力基础设施(例如，智库或研讨会)，以及 来自一个学科的科学家沉浸在其核心领域之外的学科中。每年， SPINEWORK将召集其成员参加峰会，以评估其活动，报告 调查结果，产生新的工作组，审查进展情况，并为来年制定计划。总的来说， SPINEWORK的使命是为改善腰背的治疗奠定智力基础 通过FBMS创建和培育一个多学科的、科学的和文化的 来自不同方法的不同研究人员网络，以了解FBMS 和脊椎疼痛。

Low back and neck pain, which impose major impediments to quality of life and are responsible for significant productivity loss, are often treated with expensive, sometimes ineffective, and potentially addictive drugs. Complementary therapies, especially force-based manipulations (FBMs), have the potential to address these challenges but remain poorly understood especially for spine pain. The highly multifaceted nature of FBMs complicates a complete understanding of the physiologic mechanisms involved with pain relief, requiring the integrative synthesis of neuroscience, physics, engineering, physiology, and clinical fields. To address this need, we will create a network - SPINEWORK - of researchers from all disciplines interested in exploring the potential role of FBMs in alleviating spine pain. The network will provide members with the opportunity to identify new collaborators, to learn about other disciplines, to disseminate ideas and information to their colleagues and the larger community, and to foster better interdisciplinary communication. SPINEWORK will support the network of researchers and activities administered by a set of Committees and will be organized into intersecting and evolving Working Groups, each made up of members from multiple institutions and traditional disciplines and focused on specific areas, such as Imaging or Animal Models. The Working Groups will promote interdisciplinary research through physical and virtual gatherings, white papers, journal special issues, and video content. A special Working Group on Terminology will focus on defining a common lexicon for spine pain and forced-based manipulations; this task is essential because even simple terms can have very different meaning to different communities, leading to confusion and impeding progress for collaborative teams. SPINEWORK will sponsor a pilot and facilitation grant program for interdisciplinary collaborative teams formed by its members. The grants will be focused on opportunities to seed or boost R01 proposals, activities that build intellectual infrastructure (e.g., think tanks or workshops), and opportunities for scientists from one discipline immerse in disciplines outside their core area. Annually, SPINEWORK will bring its members together for a Summit meeting to assess its activities, report findings, spawn new Working Groups, review progress, and plan for the coming year. Overall, SPINEWORK's mission is to lay the intellectual groundwork for improved treatment of low back and neck pain via FBMs by creating and fostering a multidisciplinary, scientifically and culturally diverse network of researchers from across the spectrum of approaches to understand FBMs and spine pain.