SPINE-WORK: An inclusive research community to study and improve force-based manipulations for spine pain

SPINE-WORK：一个包容性研究社区，致力于研究和改进基于力量的脊柱疼痛治疗方法

• 批准号: 10612059
• 负责人: VICTOR H BAROCAS
• 金额: $ 64.11万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-20 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10612059
• 关键词: Address; Advisory Committees; Affect; Anatomy; Animal Model; Animals; Area; Award; Biological Markers; Biomechanics; Calendar; Clinic; Clinical; Clinical Sciences; Communication; Communities; Complementary therapies; Computer Models; Confusion; Consultations; Data; Development; Discipline; Education; Educational Activities; Educational workshop; Engineering; Ensure; Event; Experimental Models; Fertilization; Focus Groups; Fostering; Goals; Grant; Health; Image; Infrastructure; Institution; Interdisciplinary Communication; Interdisciplinary Study; Intervention; Journals; Language; Learning; Low Back Pain; Manuscripts; Mission; Molecular; Musculoskeletal; Nature; Neck Pain; Neuromechanics; Neurosciences; Outcome; Pain; Pain Disorder; Pain management; Paper; Pathway interactions; Persons; Pharmaceutical Preparations; Physical therapy; Physics; Physiological; Physiology; Population; Process; Protocols documentation; Publishing; Quality of life; Reporting; Research; Research Personnel; Research Project Grants; Resources; Review Committee; Role; Scientist; Spinal Manipulation; Spine pain; Terminology; Testing; Vertebral column; Vocabulary; Work; chronic pain; diagnostic biomarker; diversity and inclusion; effective therapy; health equity; improved; in vitro Model; innovation; insight; interest; knowledge base; meetings; member; multidisciplinary; neural; non-opioid analgesic; opioid epidemic; organizational structure; outreach; pain relief; productivity loss; programs; support network; symposium; tool; virtual; web site; working group

Low back and neck pain, which impose major impediments to quality of life and are responsible for significant productivity loss, are often treated with expensive, sometimes ineffective, and potentially addictive drugs. Complementary therapies, especially force-based manipulations (FBMs), have the potential to address these challenges but remain poorly understood especially for spine pain. The highly multifaceted nature of FBMs complicates a complete understanding of the physiologic mechanisms involved with pain relief, requiring the integrative synthesis of neuroscience, physics, engineering, physiology, and clinical fields. To address this need, we will create a network - SPINEWORK - of researchers from all disciplines interested in exploring the potential role of FBMs in alleviating spine pain. The network will provide members with the opportunity to identify new collaborators, to learn about other disciplines, to disseminate ideas and information to their colleagues and the larger community, and to foster better interdisciplinary communication. SPINEWORK will support the network of researchers and activities administered by a set of Committees and will be organized into intersecting and evolving Working Groups, each made up of members from multiple institutions and traditional disciplines and focused on specific areas, such as Imaging or Animal Models. The Working Groups will promote interdisciplinary research through physical and virtual gatherings, white papers, journal special issues, and video content. A special Working Group on Terminology will focus on defining a common lexicon for spine pain and forced-based manipulations; this task is essential because even simple terms can have very different meaning to different communities, leading to confusion and impeding progress for collaborative teams. SPINEWORK will sponsor a pilot and facilitation grant program for interdisciplinary collaborative teams formed by its members. The grants will be focused on opportunities to seed or boost R01 proposals, activities that build intellectual infrastructure (e.g., think tanks or workshops), and opportunities for scientists from one discipline immerse in disciplines outside their core area. Annually, SPINEWORK will bring its members together for a Summit meeting to assess its activities, report findings, spawn new Working Groups, review progress, and plan for the coming year. Overall, SPINEWORK's mission is to lay the intellectual groundwork for improved treatment of low back and neck pain via FBMs by creating and fostering a multidisciplinary, scientifically and culturally diverse network of researchers from across the spectrum of approaches to understand FBMs and spine pain.

下背部和颈部疼痛，这是生活质量的主要障碍， 对于显著的生产力损失，通常使用昂贵的，有时无效的， 可能上瘾的药物补充疗法，特别是基于力的操作 （FBM）具有应对这些挑战的潜力，但人们对它们的了解仍然很少， 治疗脊椎疼痛FBM的高度多面性使全面理解变得复杂 疼痛缓解的生理机制，需要整合的综合 神经科学、物理学、工程学、生理学和临床领域。为了满足这一需求，我们将 创建一个网络- SPINEWORK -来自所有学科的研究人员有兴趣探索 FBM在缓解脊柱疼痛中的潜在作用。该网络将为成员提供 有机会发现新的合作者，了解其他学科，传播思想 向他们的同事和更大的社区提供信息， 跨学科交流。SPINEWORK将支持研究人员网络， 由一系列委员会管理的活动，并将组织成交叉和 不断发展的工作组，每个工作组由来自多个机构和传统 学科和专注于特定领域，如成像或动物模型。工作 小组将通过物理和虚拟聚会促进跨学科研究，白色 论文、期刊特刊和视频内容。专门的术语工作组将 重点是定义脊柱疼痛和基于强迫的操作的通用词汇;这项任务是 因为即使是简单的术语对不同的社区也有非常不同的含义， 从而导致混乱并阻碍协作团队的进展。SPINEWORK将赞助 试点和促进赠款计划，为跨学科的合作小组形成的，其 成员赠款将集中在种子或促进R 01提案，活动， 构建智能基础设施（例如，智囊团或讲习班），以及 一个学科的科学家们沉浸在他们核心领域之外的学科中。每年， SPINEWORK将召集其成员参加首脑会议，评估其活动，报告 调查结果，产生新的工作组，审查进展情况，并为来年制定计划。总的来说， SPINEWORK的使命是为改善下背部的治疗奠定知识基础 通过建立和促进多学科的，科学的和文化的 来自各种方法的研究人员组成的多元化网络，以了解FBMs 脊椎疼痛