ICSC Applied Research Project

项目概要-研究 NIH MMRRC对研究中具有科学意义的小鼠模型进行存档、管理和分发 社区以最低的成本。虽然该组织应加快研究步伐， 严格性和可重复性，没有研究表明该计划有多成功。的目标 拟议的应用研究项目是为了更好地了解MMRRC对研究的具体影响。 目标#1建议对MMRRC产品如何在全球范围内使用进行高分辨率测量。 研究频谱以及用户的详细信息。这些研究将表明， 由MMRRC支持的研究。目标#2建议通过提出问题来衡量MMRRC的影响 比如“MMRRC用户是更有效的科学家吗？”这类问题可以通过比较来回答 MMRRC产品和用户到非MMRRC产品和非用户。目标#3：发展研究 指纹有助于在缺乏唯一性的情况下唯一地识别研究产品和作者 由RRID和ORCID iD提供的标识符。这将使我们能够研究MMRRC影响的历史。研究 指纹也有助于根据研究人员的兴趣对他们进行聚类，这将使我们能够主动提出建议。 老鼠模型给有共同研究兴趣的科学家。

PROJECT SUMMARY – RESEARCH The NIH MMRRC archives, curates, and distributes mouse models of scientific interest to the research community at minimal cost. While this organization should accelerate the pace of research and provide greater rigor and reproducibility, there have been no studies that show how successful the program is. The objective of the proposed Applied Research Project is to better understand the specific impact of the MMRRC on research. Aim #1 proposes to produce high resolution measurements of how the MMRRC products are used across the research spectrum as well as details about the users. These studies will indicate the breadth and depth of research supported by the MMRRC. Aim #2 proposes to measure the impact of the MMRRC by asking questions such as “are MMRRC users more effective scientists?” This kind of question can be answered by comparing MMRRC products and users to non-MMRRC products and non-users. Aim #3 proposes to develop research fingerprints which assist in uniquely identifying research products and authors in the absence of the unique identifiers provided by RRIDs and ORCID iDs. This will allow us to study the history of MMRRC impact. Research fingerprints are also useful in clustering researchers by their interests, which will allow us to proactively suggest mouse models to scientists with shared research interests.