Biomedical Entrepreneurship Skills Development Program for the Advancement of Research Translation

促进研究转化的生物医学创业技能发展计划

• 批准号: 10462522
• 负责人: Gabrielle Gold-von Simson
• 金额: $ 10.2万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-12 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10462522
• 关键词: Applications Grants; Area; Attitude; Autoimmunity; Beds; Biological Sciences; Biomedical Technology; Businesses; Case Study; Clinical and Translational Science Awards; Communities; Complex; Consultations; Course Content; Development; Diabetes Mellitus; Disease; Dissemination and Implementation; Education; Educational Curriculum; Educational Models; Educational workshop; Effectiveness; Entrepreneurship; Evaluation; Faculty; Funding; Goals; Gold; Grant; Health; Healthcare; Individual; Industry; Inflammatory; Kidney Diseases; Knowledge; Knowledge acquisition; Learning; Learning Skill; Legal patent; Malignant Neoplasms; Measures; Medical Device; Medicine; Mentors; Metabolic Diseases; Methodology; Methods; Mission; Modeling; Modification; Molecular; Monitor; Motivation; National Institute of Diabetes and Digestive and Kidney Diseases; New York City; Obesity; Outcome; Paper; Participant; Pathogenesis; Pathway interactions; Patients; Postdoctoral Fellow; Process; Program Development; Reach Effectiveness Adoption Implementation and Maintenance; Research; Research Personnel; Running; Science; Scientist; Series; Software Tools; Sutent; Talents; Therapeutic; Translational Research; Translations; United States National Institutes of Health; Work; base; career; career development; commercialization; course implementation; course introduction; curriculum development; design; doctoral student; drug development; falls; formative assessment; improved; infliximab; innovation; interest; invention; learning materials; lectures; member; novel; programs; project-based learning; skill acquisition; skills; student training; success

Abstract: This grant proposal describes a plan to design, implement and integrate within the NYU community an educational program that teaches and trains students in Biomedical Entrepreneurship, with focus on the commercialization of academic discoveries and inventions. The program builds upon the success of the recently funded drug development educational program (NIDDK R25DK092170), developed and directed by Drs. Gold-von Simson and Ramasamy, and aims to further expand the skill set of early stage scientists to prepare them to actively participate in bed to bedside science translation. Through a variety of methods, participants will gain an understanding of the requirements for launching and building a new venture in the complex and highly regulated life sciences industry as well as the entrepreneurial journey of the scientist- entrepreneur. The program will focus on improving health innovations and developing effective solutions; this is at the core of our mentored, entrepreneurial process. We will build upon the academic excellence at NYU with its track record of success; two examples of successful collaborative discoveries at NYU led to the development of disease altering therapies like Infliximab (Remicade) and Sunitinib (Sutent). Our program aims to promote the commercial development of novel discoveries and breakthroughs, while leveraging early stage researchers with innovative and creative ideas. The goal is to teach scientists and likeminded individuals at an early career stage how to create solutions, whether at the molecular level or via the creation of medical devices or software tools, to benefit those who suffer from disease. By introducing participants to the similarities and connections between the pathogenesis mechanisms underlying diabetes and many metabolic diseases, and certain other disease areas, we will enable and encourage them to think creatively about potential applications for their own research from seemingly unrelated disease contexts such as autoimmunity and hyperimmunity, cancer, necro- inflammatory diseases and others ultimately advancing the goals of the NIDDK and the NIH as a whole. With the support of NIDDK, we can build a successful and self-sustaining biomedical entrepreneurship educational program within the NYU and New York City community and provide career development support to talented young scientists. With success of our program, we will share the curricula and methods with other US academic centers, resulting in a positive and expeditious effect on the translation of science and medicine nationally, a great mission of NIH.

摘要： 这项拨款提案描述了一项计划，以设计，实施和融入纽约大学社区， 一个教育计划，教授和培训学生在生物医学创业，重点是 学术发现和发明的商业化。该计划建立在成功的基础上， 最近资助的药物开发教育计划（NIDDK R25 DK 092170），由 Drs. Gold-von Simson和Ramasamy，旨在进一步扩展早期科学家的技能， 准备他们积极参与床到床边的科学翻译。通过各种方法， 参加者将了解在香港开办及建立新企业的要求， 复杂和高度管制的生命科学行业以及科学家的创业之旅- 企业家. 该计划将侧重于改善健康创新和开发有效的解决方案;这是核心 我们的创业过程我们将在纽约大学的学术卓越的基础上， 成功的记录;在纽约大学的两个成功的合作发现的例子导致了发展， 疾病改变疗法，如英夫利西单抗（类克）和舒尼替尼（索坦）。我们的计划旨在促进 新发现和突破的商业开发，同时利用早期研究人员 创新和创造性的想法。其目标是在职业生涯的早期向科学家和志同道合的人传授知识 阶段如何创建解决方案，无论是在分子水平上还是通过创建医疗设备或软件 工具，以造福那些患有疾病的人。通过向参与者介绍 糖尿病和许多代谢性疾病的发病机制与某些其他 在疾病领域，我们将使他们能够并鼓励他们创造性地思考自己的潜在应用， 研究从看似无关的疾病背景，如自身免疫和免疫亢进，癌症，坏死， 炎症性疾病和其他最终推进NIDDK和NIH作为一个整体的目标。 在NIDDK的支持下，我们可以建立一个成功的和自我维持的生物医学创业 在纽约大学和纽约市社区的教育计划，并提供职业发展支持， 年轻的科学家。随着我们计划的成功，我们将与其他美国人分享课程和方法。 学术中心，对科学和医学翻译产生了积极和迅速的影响 在全国范围内，这是NIH的一项伟大的使命。