Biomedical Entrepreneurship Skills Development Program for the Advancement of Research Translation

促进研究转化的生物医学创业技能发展计划

• 批准号: 10462522
• 负责人: Gabrielle Gold-von Simson
• 金额: $ 10.2万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-12 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10462522
• 关键词: Applications Grants; Area; Attitude; Autoimmunity; Beds; Biological Sciences; Biomedical Technology; Businesses; Case Study; Clinical and Translational Science Awards; Communities; Complex; Consultations; Course Content; Development; Diabetes Mellitus; Disease; Dissemination and Implementation; Education; Educational Curriculum; Educational Models; Educational workshop; Effectiveness; Entrepreneurship; Evaluation; Faculty; Funding; Goals; Gold; Grant; Health; Healthcare; Individual; Industry; Inflammatory; Kidney Diseases; Knowledge; Knowledge acquisition; Learning; Learning Skill; Legal patent; Malignant Neoplasms; Measures; Medical Device; Medicine; Mentors; Metabolic Diseases; Methodology; Methods; Mission; Modeling; Modification; Molecular; Monitor; Motivation; National Institute of Diabetes and Digestive and Kidney Diseases; New York City; Obesity; Outcome; Paper; Participant; Pathogenesis; Pathway interactions; Patients; Postdoctoral Fellow; Process; Program Development; Reach Effectiveness Adoption Implementation and Maintenance; Research; Research Personnel; Running; Science; Scientist; Series; Software Tools; Sutent; Talents; Therapeutic; Translational Research; Translations; United States National Institutes of Health; Work; base; career; career development; commercialization; course implementation; course introduction; curriculum development; design; doctoral student; drug development; falls; formative assessment; improved; infliximab; innovation; interest; invention; learning materials; lectures; member; novel; programs; project-based learning; skill acquisition; skills; student training; success

Abstract: This grant proposal describes a plan to design, implement and integrate within the NYU community an educational program that teaches and trains students in Biomedical Entrepreneurship, with focus on the commercialization of academic discoveries and inventions. The program builds upon the success of the recently funded drug development educational program (NIDDK R25DK092170), developed and directed by Drs. Gold-von Simson and Ramasamy, and aims to further expand the skill set of early stage scientists to prepare them to actively participate in bed to bedside science translation. Through a variety of methods, participants will gain an understanding of the requirements for launching and building a new venture in the complex and highly regulated life sciences industry as well as the entrepreneurial journey of the scientist- entrepreneur. The program will focus on improving health innovations and developing effective solutions; this is at the core of our mentored, entrepreneurial process. We will build upon the academic excellence at NYU with its track record of success; two examples of successful collaborative discoveries at NYU led to the development of disease altering therapies like Infliximab (Remicade) and Sunitinib (Sutent). Our program aims to promote the commercial development of novel discoveries and breakthroughs, while leveraging early stage researchers with innovative and creative ideas. The goal is to teach scientists and likeminded individuals at an early career stage how to create solutions, whether at the molecular level or via the creation of medical devices or software tools, to benefit those who suffer from disease. By introducing participants to the similarities and connections between the pathogenesis mechanisms underlying diabetes and many metabolic diseases, and certain other disease areas, we will enable and encourage them to think creatively about potential applications for their own research from seemingly unrelated disease contexts such as autoimmunity and hyperimmunity, cancer, necro- inflammatory diseases and others ultimately advancing the goals of the NIDDK and the NIH as a whole. With the support of NIDDK, we can build a successful and self-sustaining biomedical entrepreneurship educational program within the NYU and New York City community and provide career development support to talented young scientists. With success of our program, we will share the curricula and methods with other US academic centers, resulting in a positive and expeditious effect on the translation of science and medicine nationally, a great mission of NIH.

抽象的： 该拨款提案描述了一项在纽约大学社区内设计、实施和整合的计划 教授和培训学生生物医学创业的教育计划，重点关注 学术发现和发明的商业化。该计划建立在 最近资助的药物开发教育计划（NIDDK R25DK092170），由 博士。 Gold-von Simson 和 Ramasamy，旨在进一步扩展早期科学家的技能 准备他们积极参与床边科学转化。通过多种方式， 参与者将了解在该地区启动和建立新企业的要求 复杂且监管严格的生命科学行业以及科学家的创业之旅—— 企业家。 该计划将重点关注改善健康创新和开发有效的解决方案；这是核心 我们的指导创业过程。我们将在纽约大学的学术卓越基础上建立其轨道 成功记录；纽约大学成功合作发现的两个例子导致了 疾病改变疗法，如英夫利昔单抗 (Remicade) 和舒尼替尼 (Sutent)。我们的计划旨在促进 新发现和突破的商业开发，同时利用早期研究人员 具有创新和创意的想法。目标是在早期职业生涯中教授科学家和志同道合的人 阶段如何创建解决方案，无论是在分子水平还是通过创建医疗设备或软件 工具，造福那些患有疾病的人。通过向参与者介绍相似之处和联系 糖尿病和许多代谢性疾病以及某些其他疾病的发病机制之间的关系 疾病领域，我们将帮助并鼓励他们创造性地思考自己的潜在应用 来自看似无关的疾病背景的研究，例如自身免疫和超免疫、癌症、坏死性 炎症性疾病和其他疾病最终推进 NIDDK 和 NIH 的整体目标。 在NIDDK的支持下，我们可以建立一个成功的、自我维持的生物医药创业企业 纽约大学和纽约市社区内的教育计划，并为以下人员提供职业发展支持 有才华的年轻科学家。随着我们项目的成功，我们将与美国其他国家分享课程和方法 学术中心，对科学和医学的翻译产生积极而迅速的影响 在全国范围内，这是 NIH 的一项伟大使命。