Multidisciplinary Training in Translational Gastrinointestinal and Liver Research

项目摘要 这是哥伦比亚大学瓦格洛斯内外科医学院的更新申请， 消化和肝脏疾病博士后培养计划。该计划的使命是培养医学博士和 MD/PhD学员将成为胃肠病学的独立基础，临床和转化研究人员， 肝病学该计划已经存在了九年，迄今为止，一直非常成功，在这方面， 使命。学员是从内科系和内科系的胃肠病学研究员中挑选出来的。 哥伦比亚的儿科。医学和儿科的胃肠病学奖学金项目多种多样， 竞争力强，并把主要重点放在研究培训的选择和培训，他们的 伙计们这为培训方案提供了一个非常强大的申请人库。而且 培训方案成功地从代表性不足的国家招募了优秀学员，并将继续这样做 少数群体。该计划的教师是多学科的，包括导师不仅在系 医学和儿科系，以及哥伦比亚的其他系、研究所和中心 大学大多数导师都是知名的，NIH资助的研究人员，但也有一些早期的初级研究人员。 此外，亦包括与资深导师配对以进行培训的导师。学员选择 在三个广泛的主题领域进行研究- 1）基础胃肠病学研究，2）基础肝脏研究 以及3）临床流行病学/精确医学-并在其中一个领域选择一名导师。学员奉献 他们的大部分精力都用于指导研究项目，但也要完成严格的教学计划， 包括，如果他们愿意，获得临床研究硕士学位的机会。此外，强 重点是在负责任地进行研究以及严谨性和可重复性方面进行培训。博士 蒂莫西·C王先生担任该培训计划的总监，并由副总监王博士及王先生的助理协助。 乔尔·拉文和霍华德·沃曼。每个人都有富有成效的，积极的研究计划， 在博士后培训和医学教育方面有着卓越的记录。该计划得到了 哥伦比亚的机构领导人内部咨询委员会和 在其他机构的胃肠病学和肝病学的领先研究人员。培训计划利用 哥伦比亚大学的其他NIH资助的实体，包括其临床和转化科学奖 该培训计划将继续产生卓越的 胃肠病学和肝病基础和临床研究的医生-研究者， 为我国的公共卫生做出了重大贡献。

Project Summary This is a renewal application from the Columbia University's Vagelos College of Physicians and Surgeons for its postdoctoral training program in digestive and liver diseases. The program's mission is to train MD and MD/PhD trainees to become independent basic, clinical and translational researchers in gastroenterology and hepatology. The program has been in existence for nine years to date and has been highly successful in this mission. Trainees are selected from gastroenterology fellows in the Department of Medicine and Department of Pediatrics at Columbia. The gastroenterology fellowship programs in both Medicine and Pediatrics are diverse, highly competitive and put a primary emphasis on research training in both the selection and training of their fellows. This provides for an exceptionally strong pool of applicants to the training program. Furthermore, the training programs has succeeded in and will continue to recruit outstanding trainees from underrepresented minority groups. The program faculty is multidisciplinary and includes mentors not only in the Department of Medicine and Department of Pediatrics but also in other departments, institutes and centers at Columbia University. Most of the mentors are well-established, NIH-funded investigators but several early-stage junior mentors, who are paired with established mentors for training purposes, are also included. Trainees chose to pursue research in three broad thematic areas – 1) basic gastroenterology research, 2) basic liver research and 3) clinical epidemiology/precision medicine – and select a mentor in one of these areas. Trainees devote most of their effort to a mentored research project but also complete a rigorous program of didactic instruction, including, if they chose, the opportunity to obtain a master's degree in clinical research. In addition, strong emphasis is given to training in the responsible conduct of research and in rigor and reproducibility. Dr. Timothy C. Wang serves as Director of this training program and is ably assisted by Associate Directors Drs. Joel Lavine and Howard Worman. Each of these individuals have productive, active research programs and superb track records in postdoctoral training and medical education. The program is supported by both an Internal Advisory Committee of institutional leaders at Columbia and an External Advisory Committee of leading researchers in gastroenterology and hepatology at other institutions. The training program leverages other NIH-funded entities at Columbia University, including its Clinical and Translational Science Award program and educational programs within it. This training program will continue to produce exceptional physician-investigators in basic and clinical research in gastroenterology and liver diseases who will make significant contributions to our nation's public health.