Multidisciplinary Training in Translational Gastrinointestinal and Liver Research

项目摘要 这是哥伦比亚大学Vagelos内科和外科医学院的续签申请 它的消化和肝病博士后培训计划。该项目的任务是培养医学博士和 MD/PHD实习生将成为胃肠病学和翻译领域的独立基础、临床和翻译研究人员 肝病。到目前为止，该计划已经存在了九年，并在这方面取得了巨大的成功 任务。学员是从内科和医学系的消化内科研究员中挑选出来的 哥伦比亚大学儿科。内科和儿科的胃肠病奖学金项目是多种多样的， 具有很强的竞争力，在选拔和培训他们的过程中，主要强调研究性培训 伙计们。这为培训计划提供了一个特别强大的申请者池。此外， 培训方案已经成功地并将继续从任职人数不足的人中招募优秀的受训人员 少数群体。该计划的教职员工是多学科的，不仅包括系内的导师 医学和儿科，以及哥伦比亚大学的其他部门、研究所和中心 大学。大多数导师都是由美国国立卫生研究院资助的知名研究人员，但也有几位初出茅庐 导师也被包括在内，他们与成熟的导师配对进行培训。学员们选择了 从事三大主题领域的研究-1)基础胃肠病研究，2)基础肝脏研究 3)临床流行病学/精准医学--并在这些领域中选择一位导师。实习生致力于 他们的大部分努力都是为了完成一个有指导的研究项目，同时也完成了一个严格的教学计划， 如果他们愿意的话，包括获得临床研究硕士学位的机会。此外，强势 重点是负责任地进行研究以及严谨和可重复性方面的培训。Dr。 蒂莫西·C·王担任这一培训项目的主任，并得到副主任Dr。 乔尔·拉文和霍华德·沃曼。这些人中的每一个都有富有成效的、积极的研究计划和 在博士后培训和医学教育方面有出色的记录。该计划受到两家公司的支持 哥伦比亚大学机构领导人内部咨询委员会和 其他机构在胃肠病和肝病方面的领先研究人员。该培训计划利用 其他由美国国立卫生研究院资助的哥伦比亚大学实体，包括临床和翻译科学奖 计划和其中的教育计划。这一培训计划将继续产生非凡的 内科医生-胃肠病和肝病基础和临床研究的调查员 对我们国家的公共卫生做出了重大贡献。

Project Summary This is a renewal application from the Columbia University's Vagelos College of Physicians and Surgeons for its postdoctoral training program in digestive and liver diseases. The program's mission is to train MD and MD/PhD trainees to become independent basic, clinical and translational researchers in gastroenterology and hepatology. The program has been in existence for nine years to date and has been highly successful in this mission. Trainees are selected from gastroenterology fellows in the Department of Medicine and Department of Pediatrics at Columbia. The gastroenterology fellowship programs in both Medicine and Pediatrics are diverse, highly competitive and put a primary emphasis on research training in both the selection and training of their fellows. This provides for an exceptionally strong pool of applicants to the training program. Furthermore, the training programs has succeeded in and will continue to recruit outstanding trainees from underrepresented minority groups. The program faculty is multidisciplinary and includes mentors not only in the Department of Medicine and Department of Pediatrics but also in other departments, institutes and centers at Columbia University. Most of the mentors are well-established, NIH-funded investigators but several early-stage junior mentors, who are paired with established mentors for training purposes, are also included. Trainees chose to pursue research in three broad thematic areas – 1) basic gastroenterology research, 2) basic liver research and 3) clinical epidemiology/precision medicine – and select a mentor in one of these areas. Trainees devote most of their effort to a mentored research project but also complete a rigorous program of didactic instruction, including, if they chose, the opportunity to obtain a master's degree in clinical research. In addition, strong emphasis is given to training in the responsible conduct of research and in rigor and reproducibility. Dr. Timothy C. Wang serves as Director of this training program and is ably assisted by Associate Directors Drs. Joel Lavine and Howard Worman. Each of these individuals have productive, active research programs and superb track records in postdoctoral training and medical education. The program is supported by both an Internal Advisory Committee of institutional leaders at Columbia and an External Advisory Committee of leading researchers in gastroenterology and hepatology at other institutions. The training program leverages other NIH-funded entities at Columbia University, including its Clinical and Translational Science Award program and educational programs within it. This training program will continue to produce exceptional physician-investigators in basic and clinical research in gastroenterology and liver diseases who will make significant contributions to our nation's public health.