The UNC Core Center for Clinical Research: Admin Core

摘要 – 行政核心 行政核心的目的是提供领导、监督、协调和 为北卡罗来纳大学 (UNC) 核心中心的所有活动提供一般行政支持 临床研究（CCCR）。行政核心的具体目标是最大限度地提高科学性 CCCR 工作的完整性和传播，重点是优化临床研究和 临床试验将促进针对患有此类疾病的个人的临床护理和公共卫生工作 骨关节炎 (OA) 和其他风湿病和肌肉骨骼疾病 (RMD)。 该核心将促进我们提供的新颖、创新和令人兴奋的服务的交付 我们的研究社区的方法论以及我们的表型和精准医学资源核心： 北卡罗来纳大学，整个北卡罗来纳州 (NC) 及其他地区。我们的研究社区还包括 内部 (IAB) 和外部 (EAB) 顾问委员会成员，以及与 NC 的具体合作 转化和临床科学研究所 (NC TraCS)，我们临床和转化科学的所在地 CCCR 将以当前多学科临床研究中心 (MCRC) 的巨大成功为基础 位于瑟斯顿关节炎研究中心 (TARC)，旨在减轻 OA 对公共健康的影响。的 CCCR 将利用 TARC 的沟通和发展官员以及骨关节炎行动 联盟 (OAAA)，由 100 多个组织组成的联盟，致力于将 OA 提升为国民健康水平 优先权，位于拉曼大学拉曼学院。 行政核心的目的将通过以下具体目标来实现： 1) 提供 领导力和愿景指导 CCCR 重点优化临床研究和临床试验， 推进针对 OA 和其他 RMD 患者的临床护理和公共卫生工作 NIAMS 的使命； 2) 为方法论提供监督、协调和一般行政支持 核心、表型和精准医学资源核心、试点和可行性资助计划以及 他们的目标，包括培训学生和初级研究人员； 3) 提供结构和监督 CCCR 与 TARC 正在进行的广泛研究活动之间的互动和沟通， OAAA、NC TraCS 和其他 UNC 学校、部门、中心和项目，以及公立和私立学校 国家、国家和国际各级的私人组织； 4) 保持系统间的通信联系 执行委员会、方法学核心、表型分析和精准医学资源核心、IAB、EAB、 利益相关者咨询委员会 (SAB)、CCCR 研究社区和其他 NIAMS 资助的 CCCR； 5） 对 CCCR 活动进行持续评价和评估，以确保目标、预期成果和 满足申请中规定的输出。

ABSTRACT – ADMINISTRATIVE CORE The purpose of the Administrative Core is to provide leadership, oversight, coordination, and general administrative support for all activities of the University of North Carolina (UNC) Core Center for Clinical Research (CCCR). The Administrative Core's specific goal is to maximize the scientific integrity and dissemination of the CCCR's work, which is focused on optimizing clinical research and clinical trials that will advance clinical care and public health efforts targeted toward individuals with osteoarthritis (OA) and other Rheumatic and Musculoskeletal Diseases (RMDs). This Core will facilitate the delivery of novel, innovative, and exciting services provided by our Methodology and our Phenotyping and Precision Medicine Resource Cores to our research community at UNC, throughout the state of North Carolina (NC) and beyond. Our research community also includes members of the Internal (IAB) and External (EAB) Advisory Boards, and specific collaborations with the NC Translational and Clinical Sciences Institute (NC TraCS), home to our Clinical and Translational Science This CCCR will build on the strong success of the current Multidisciplinary Clinical Research Center (MCRC) housed at the Thurston Arthritis Research Center (TARC), Mitigating the Public Health Impact of OA. The CCCR will leverage TARC's Communications and Development Officers, as well as the Osteoarthritis Action Alliance (OAAA), a coalition of more than 100 organizations committed to elevating OA as a national health priority, which is housed at TARC. The Administrative Core's purpose will be accomplished through the following specific aims: 1) Provide leadership and vision to guide the CCCR in its focus on optimizing clinical research and clinical trials to advance clinical care and public health efforts targeted toward people with OA and other RMDs within the mission of NIAMS; 2) Provide oversight, coordination and general administrative support to the Methodology Core, Phenotyping and Precision Medicine Resource Core, and the Pilot and Feasibility grant program and their goals, including the training of students and junior investigators; 3) Provide structure and oversight of interactions and communications between the CCCR and the extensive ongoing TARC research activities, OAAA, NC TraCS, and other UNC Schools, Departments, Centers, and Programs, as well as with public and private organizations at the state, national, and international levels; 4) Maintain communication links among the Executive Committee, Methodology Core, Phenotyping and Precision Medicine Resource Core, IAB, EAB, Stakeholder Advisory Board (SAB), the CCCR Research Community, and the other NIAMS funded CCCRs; 5) Conduct ongoing evaluation and assessment of CCCR activities to ensure that goals, expected outcomes and outputs set forth in the application are met.