The UNC Core Center for Clinical Research: Admin Core

摘要-行政核心 行政核心的目的是提供领导、监督、协调和 为北卡罗来纳州（UNC）核心中心的所有活动提供一般行政支持 临床研究（CCCR）。行政核心的具体目标是最大限度地科学化 CCCR工作的完整性和传播，其重点是优化临床研究， 临床试验，将促进针对个人的临床护理和公共卫生工作， 骨关节炎（OA）和其他风湿性和肌肉骨骼疾病（RMD）。 这一核心将促进提供新颖的，创新的，令人兴奋的服务，由我们的 方法学和我们的表型和精准医学资源核心，我们的研究社区， 在整个北卡罗来纳州（NC）和更远的地方。我们的研究社区还包括 内部（IAB）和外部（EAB）咨询委员会的成员，以及与NC的具体合作 转化和临床科学研究所（NC TraCS），我们的临床和转化科学的所在地 CCCR将建立在当前多学科临床研究中心（MCRC）的巨大成功基础上 Thurston关节炎研究中心（TARC），减轻OA对公共卫生的影响。的 CCCR将利用TARC的通信和发展官员，以及骨关节炎行动 联盟（OAAA），一个由100多个组织组成的联盟，致力于将OA提升为国家健康 优先权，这是安置在TARC。 行政核心的目的将通过以下具体目标实现：1）提供 领导力和愿景，以指导CCCR专注于优化临床研究和临床试验， 推进针对OA和其他RMD患者的临床护理和公共卫生工作， 国家机构间评估和监测系统的使命; 2）为该方法提供监督、协调和一般行政支助 核心，表型和精准医学资源核心，以及试点和可行性赠款计划， 他们的目标，包括学生和初级研究人员的培训; 3）提供结构和监督， CCCR与正在进行的广泛的TARC研究活动之间的互动和沟通， OAAA，NC TraCS和其他学校，部门，中心和计划，以及与公共和 4.在国家、国家和国际各级的私人组织; 4.保持 执行委员会，方法学核心，表型和精准医学资源核心，IAB，EAB， 利益相关者咨询委员会（SAB）、CCCR研究社区和其他NIAMS资助的CCCR; 5） 对CCCR活动进行持续的评价和评估，以确保目标、预期成果和 满足申请中规定的产出。

ABSTRACT – ADMINISTRATIVE CORE The purpose of the Administrative Core is to provide leadership, oversight, coordination, and general administrative support for all activities of the University of North Carolina (UNC) Core Center for Clinical Research (CCCR). The Administrative Core's specific goal is to maximize the scientific integrity and dissemination of the CCCR's work, which is focused on optimizing clinical research and clinical trials that will advance clinical care and public health efforts targeted toward individuals with osteoarthritis (OA) and other Rheumatic and Musculoskeletal Diseases (RMDs). This Core will facilitate the delivery of novel, innovative, and exciting services provided by our Methodology and our Phenotyping and Precision Medicine Resource Cores to our research community at UNC, throughout the state of North Carolina (NC) and beyond. Our research community also includes members of the Internal (IAB) and External (EAB) Advisory Boards, and specific collaborations with the NC Translational and Clinical Sciences Institute (NC TraCS), home to our Clinical and Translational Science This CCCR will build on the strong success of the current Multidisciplinary Clinical Research Center (MCRC) housed at the Thurston Arthritis Research Center (TARC), Mitigating the Public Health Impact of OA. The CCCR will leverage TARC's Communications and Development Officers, as well as the Osteoarthritis Action Alliance (OAAA), a coalition of more than 100 organizations committed to elevating OA as a national health priority, which is housed at TARC. The Administrative Core's purpose will be accomplished through the following specific aims: 1) Provide leadership and vision to guide the CCCR in its focus on optimizing clinical research and clinical trials to advance clinical care and public health efforts targeted toward people with OA and other RMDs within the mission of NIAMS; 2) Provide oversight, coordination and general administrative support to the Methodology Core, Phenotyping and Precision Medicine Resource Core, and the Pilot and Feasibility grant program and their goals, including the training of students and junior investigators; 3) Provide structure and oversight of interactions and communications between the CCCR and the extensive ongoing TARC research activities, OAAA, NC TraCS, and other UNC Schools, Departments, Centers, and Programs, as well as with public and private organizations at the state, national, and international levels; 4) Maintain communication links among the Executive Committee, Methodology Core, Phenotyping and Precision Medicine Resource Core, IAB, EAB, Stakeholder Advisory Board (SAB), the CCCR Research Community, and the other NIAMS funded CCCRs; 5) Conduct ongoing evaluation and assessment of CCCR activities to ensure that goals, expected outcomes and outputs set forth in the application are met.