The UNC Core Center for Clinical Research: Admin Core

抽象行政核心 行政核心的目的是提供领导、监督、协调和 对北卡罗来纳大学(北卡罗来纳大学)核心中心所有活动的一般行政支助 临床研究(CCCR)。行政核心的具体目标是最大限度地发挥科学 CCCR工作的完整性和传播，其重点是优化临床研究和 临床试验将促进临床护理和公共卫生努力，针对患有 骨关节炎(OA)和其他风湿性和肌肉骨骼疾病(RMD)。 这一核心将促进我们提供的创新和令人兴奋的服务 方法学和我们的表型和精确医学资源核心提供给我们的研究社区，网址为 北卡罗来纳州(北卡罗来纳州)及更远地区。我们的研究社区还包括 内部(IAB)和外部(EAB)咨询委员会成员，以及与NC的具体合作 翻译和临床科学研究所(NC TraCS)，我们的临床和翻译科学的大本营 CCCR将在目前多学科临床研究中心(MCRC)取得巨大成功的基础上再接再厉 位于瑟斯顿关节炎研究中心(TARC)，减轻了关节炎对公共卫生的影响。这个 CCCR将利用TARC的通信和发展官员以及骨性关节炎行动 联盟(OAAA)，一个由100多个组织组成的联盟，致力于将OA提升为国民健康 PRIORITY，位于TARC。 行政核心的目标将通过以下具体目标来实现：1)提供 领导和远见，指导CCCR专注于优化临床研究和临床试验，以 推进临床护理和公共卫生努力，针对骨性关节炎和其他RMD患者 NIAMS的使命；2)为方法学提供监督、协调和一般行政支助 核心，表型和精确医学资源核心，以及试点和可行性赠款计划和 他们的目标，包括培训学生和初级调查员；3)提供结构和监督 CCCR与正在进行的广泛的TARC研究活动之间的互动和交流， OAAA、NC TraCS和其他北卡罗来纳大学的学校、部门、中心和计划，以及与公共和 国家、国家和国际各级的私营组织；4)在国家、国家和国际各级 执行委员会，方法学核心，表型和精确医学资源核心，IAB， 利益攸关方咨询委员会(SAB)、CCCR研究社区和其他由NIAMS资助的CCCR；5) 对CCCR活动进行持续评价和评估，以确保目标、预期成果和 符合申请中规定的产出。

ABSTRACT – ADMINISTRATIVE CORE The purpose of the Administrative Core is to provide leadership, oversight, coordination, and general administrative support for all activities of the University of North Carolina (UNC) Core Center for Clinical Research (CCCR). The Administrative Core's specific goal is to maximize the scientific integrity and dissemination of the CCCR's work, which is focused on optimizing clinical research and clinical trials that will advance clinical care and public health efforts targeted toward individuals with osteoarthritis (OA) and other Rheumatic and Musculoskeletal Diseases (RMDs). This Core will facilitate the delivery of novel, innovative, and exciting services provided by our Methodology and our Phenotyping and Precision Medicine Resource Cores to our research community at UNC, throughout the state of North Carolina (NC) and beyond. Our research community also includes members of the Internal (IAB) and External (EAB) Advisory Boards, and specific collaborations with the NC Translational and Clinical Sciences Institute (NC TraCS), home to our Clinical and Translational Science This CCCR will build on the strong success of the current Multidisciplinary Clinical Research Center (MCRC) housed at the Thurston Arthritis Research Center (TARC), Mitigating the Public Health Impact of OA. The CCCR will leverage TARC's Communications and Development Officers, as well as the Osteoarthritis Action Alliance (OAAA), a coalition of more than 100 organizations committed to elevating OA as a national health priority, which is housed at TARC. The Administrative Core's purpose will be accomplished through the following specific aims: 1) Provide leadership and vision to guide the CCCR in its focus on optimizing clinical research and clinical trials to advance clinical care and public health efforts targeted toward people with OA and other RMDs within the mission of NIAMS; 2) Provide oversight, coordination and general administrative support to the Methodology Core, Phenotyping and Precision Medicine Resource Core, and the Pilot and Feasibility grant program and their goals, including the training of students and junior investigators; 3) Provide structure and oversight of interactions and communications between the CCCR and the extensive ongoing TARC research activities, OAAA, NC TraCS, and other UNC Schools, Departments, Centers, and Programs, as well as with public and private organizations at the state, national, and international levels; 4) Maintain communication links among the Executive Committee, Methodology Core, Phenotyping and Precision Medicine Resource Core, IAB, EAB, Stakeholder Advisory Board (SAB), the CCCR Research Community, and the other NIAMS funded CCCRs; 5) Conduct ongoing evaluation and assessment of CCCR activities to ensure that goals, expected outcomes and outputs set forth in the application are met.