Developmental Research Program
Developmental Research Program
批准号:
10474305
负责人:
Ross L Levine
金额:
$7.33万
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
未结题
起止时间:
2021-08-24 至 2026-06-30
关键词:
AddressBasic ScienceBiological MarkersBloodClinicalClinical SciencesClinical TrialsCollaborationsCommunitiesCommunity PhysicianComputing MethodologiesDevelopmentDiagnosisDisease ManagementDoctor of PhilosophyFacultyFundingGoalsGrantHematologic NeoplasmsHomeImmunologyIncubatorsIndividualInstitutionInvestigationMalignant NeoplasmsMemorial Sloan-Kettering Cancer CenterMolecular GeneticsMonitorOncologyPathogenesisPatientsPeer ReviewPilot ProjectsPoliciesPreventionProceduresProgram Research Project GrantsRefractoryRelapseResearchResearch PersonnelResearch Project GrantsResearch ProposalsResearch SupportScienceScientistSeedsSeriesTalentsTechnologyTranslational ResearchTreatment ProtocolsUnderrepresented MinorityUniversitiesWomanWorkbasebench to bedsideclinical predictorshigh rewardhigh riskimprovedinnovationleukemialeukemia treatmentmedical schoolsmeetingsmembernew technologynovelnovel strategiesprogramsrelapse patientsresponsetargeted treatmenttherapy resistanttranslational cancer researchtreatment responseworking group
中文摘要
点击翻译按钮获取中文摘要
英文摘要
ABSTRACT
The goal of the Developmental Research Program (DRP) of the Memorial Sloan Kettering Cancer Center
Leukemia SPORE is to provide seed funding for pilot projects that show potential to make meaningful
advances in leukemia prevention, diagnosis, and/or treatment. Supplemented by institutional funds, the DRP
will provide one to two years of funding to talented investigators or research teams from clinical and/or basic
science backgrounds from the MSK community, neighboring institutions, or in support of collaborations with
other Leukemia SPOREs. We will invite candidates annually to submit research proposals for peer-review by
a committee of experts in leukemia and translational cancer research. We will prioritize research proposals that
describe high-risk/high-reward hypothesis-driven work that has the potential to advance new avenues of
leukemia investigation, or proposals that bring together exciting collaborative teams who will address ongoing
problems in the leukemia field using new approaches and technologies. Applicants for DRP funding should
possess an MD and/or PhD degree and should hold independent-investigator status as a faculty member or
clinical researcher/research scientist at their institution. Applicants should have demonstrated a clear
commitment to translational cancer research related to leukemia. The DRP investigators will be considered full
members of the MSK SPORE in Leukemia and will participate ongoing meetings and research seminars
(regular meetings and seminars held by the Leukemia Working Group, Leukemia Disease Management Team,
Center of Hematologic Malignancies Science in Focus) as well as specialized SPORE meetings (annual, multi-
institutional SPORE Retreat; SPORE Seminar Series; monthly progress meetings). The DRP projects will be
monitored by the Executive Committee at monthly progress meetings, and will be reviewed to evaluate
potential to grow into a full SPORE research project in the current or upcoming grant cycle. The DRP
is committed to adhering to and supporting the MSK policies and procedures to promote diversity and
strengthen the participation of women and individuals from underrepresented minorities.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Assessing the Interplay Between Inflammatory Signaling and Epigenetic Dysregulation in Age-associated Clonal Hematopoiesis and Leukemia Initiation
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批准号:10291637
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项目类别:
-
资助金额:$53.8万
-
财政年份:2021
-
负责人:Ross L Levine
-
依托单位:
Assessing the Interplay Between Inflammatory Signaling and Epigenetic Dysregulation in Age-associated Clonal Hematopoiesis and Leukemia Initiation
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批准号:10659254
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项目类别:
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资助金额:$51.55万
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财政年份:2021
-
负责人:Ross L Levine
-
依托单位:
Assessing the Interplay Between Inflammatory Signaling and Epigenetic Dysregulation in Age-associated Clonal Hematopoiesis and Leukemia Initiation
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批准号:10488271
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项目类别:
-
资助金额:$51.81万
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财政年份:2021
-
负责人:Ross L Levine
-
依托单位:
Project 1: Increasing therapeutic efficacy in isocitrate dehydrongenase (IDH)–mutant acute myeloid leukemia (AML)
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批准号:10474275
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项目类别:
-
资助金额:$36.77万
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财政年份:2021
-
负责人:Ross L Levine
-
依托单位:
Synergistic role of signaling and epigenetics in leukemic transformation
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批准号:10323022
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项目类别:
-
资助金额:$105.6万
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财政年份:2017
-
负责人:Ross L Levine
-
依托单位:
Synergistic role of signaling and epigenetics in leukemic transformation
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批准号:10543794
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项目类别:
-
资助金额:$105.6万
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财政年份:2017
-
负责人:Ross L Levine
-
依托单位:
Synergistic role of signaling and epigenetics in leukemic transformation
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批准号:10737736
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项目类别:
-
资助金额:$106.2万
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财政年份:2017
-
负责人:Ross L Levine
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依托单位:
Synergistic role of signaling and epigenetics in leukemic transformation
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批准号:10078940
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项目类别:
-
资助金额:$107.76万
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财政年份:2017
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负责人:Ross L Levine
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依托单位:
ECOG-ACRIN INTEGRATED LEUKEMIA TRANSLATIONAL RESEARCH CENTER
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批准号:9235262
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项目类别:
-
资助金额:$60.0万
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财政年份:2014
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负责人:Ross L Levine
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依托单位:
ECOG-ACRIN INTEGRATED LEUKEMIA TRANSLATIONAL RESEARCH CENTER
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批准号:8605643
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项目类别:
-
资助金额:$60.0万
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财政年份:2014
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负责人:Ross L Levine
-
依托单位:
ECOG-ACRIN INTEGRATED LEUKEMIA TRANSLATIONAL RESEARCH CENTER
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批准号:9031084
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项目类别:
-
资助金额:$60.0万
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财政年份:2014
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负责人:Ross L Levine
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依托单位:
Molecular Pathogenesis and Therapy of ET and PMF
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批准号:9185463
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项目类别:
-
资助金额:$40.71万
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财政年份:2010
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负责人:Ross L Levine
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依托单位:
Molecular Pathogenesis and Therapy of ET and PMF
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批准号:8403844
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项目类别:
-
资助金额:$40.63万
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财政年份:2010
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负责人:Ross L Levine
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依托单位:
Molecular Pathogenesis and Therapy of ET and PMF
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批准号:8208241
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项目类别:
-
资助金额:$43.23万
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财政年份:2010
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负责人:Ross L Levine
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依托单位:
Molecular Pathogenesis and Therapy of ET and PMF
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批准号:8586237
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项目类别:
-
资助金额:$41.93万
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财政年份:2010
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负责人:Ross L Levine
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依托单位:
Molecular Pathogenesis and Therapy of ET and PMF
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批准号:8097381
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项目类别:
-
资助金额:$43.23万
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财政年份:2010
-
负责人:Ross L Levine
-
依托单位:
Dynamics of Tumor Stem Cells in Cancer Initiation, Therapy, and Resistance
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批准号:8119712
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项目类别:
-
资助金额:$48.73万
-
财政年份:2008
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负责人:Ross L Levine
-
依托单位:
High Throughput Screen for JAK2V617F Mutant Selective Inhibitors
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批准号:7522193
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项目类别:
-
资助金额:$2.5万
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财政年份:2008
-
负责人:Ross L Levine
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依托单位:
Dynamics of Tumor Stem Cells in Cancer Initiation, Therapy, and Resistance
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批准号:8326199
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项目类别:
-
资助金额:$47.5万
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财政年份:2008
-
负责人:Ross L Levine
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依托单位:
Dynamics of Tumor Stem Cells in Cancer Initiation, Therapy, and Resistance
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批准号:8235208
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项目类别:
-
资助金额:$46.02万
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财政年份:2008
-
负责人:Ross L Levine
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依托单位:
海外基金