Social determinants of cardiovascular disease risk over the life course

生命历程中心血管疾病风险的社会决定因素

• 批准号: 10483129
• 负责人: ANA V DIEZ-ROUX
• 金额: $ 24.62万
• 依托单位: DREXEL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10483129
• 关键词: Americas; Applications Grants; Cardiovascular Diseases; Central America; Central American; Cities; Collaborations; Communities; Country; Data Analytics; Development; Doctor' s Degree; Educational workshop; Elements; Faculty; Healthcare; Healthcare Systems; Incidence; Income; Information Dissemination; Institutes; Interdisciplinary Study; Intervention; Journals; Lead; Life Cycle Stages; Life course epidemiology; Longevity; Master' s Degree; Mentors; Mentorship; Methods; Neighborhoods; Panama; Periodicity; Persons; Phase; Policies; Policy Maker; Postdoctoral Fellow; Prevalence; Public Health; Public Policy; Publications; Research; Research Methodology; Research Personnel; Risk Factors; Site; Students; Training; Training Activity; Training Programs; Translational Research; Translations; Universities; Urbanization; Visit; base; cardiovascular disorder risk; data management; doctoral student; interdisciplinary approach; mid-career faculty; nutrition; prevent; programs; research data dissemination; social; social determinants; social health determinants; social influence; webinar

PROJECT SUMMARY Over the last several decades, cardiovascular disease (CVD) incidence and the prevalence of CVD risk factors have steadily increased in the Central American region, in contrast to other countries of the Americas where CVD is no longer increasing or on the decline. The rise of CVD in the region has occurred in tandem with increases in urbanization and widening social inequities, and poses a growing, untenable burden for its limited public health and health care systems. While research in high income countries highlights interventions on social determinants of health as levers to prevent cardiovascular disease, less is known about the specific, intervenable social determinants that can help prevent CVD in Central America. Training and mentoring of the local workforce in identifying relevant research questions, in the use of appropriate research methods, and in the dissemination of results to the scientific community, the public, and policy makers is critical to identify and develop interventions to prevent CVD in the region. To this end, researchers from Drexel University and the Institute for Nutrition of Central America and Panama (INCAP) have partnered to establish a training program focused on developing the research capabilities of trainees and local capacity building in the conduct of policy- relevant research on the influence of social determinants and place-based factors on CVD risk across the lifespan. Key elements include: (1) a focus on factors at multiple levels (from cities, to neighborhoods, to persons) and over the lifecourse, (2) the use of rigorous state-of-the-art methods; (3) an emphasis on the value of interdisciplinary approaches; and (4) dissemination and translation of research findings into policy actions. The program leverages the SALURBAL Study, a unique multidisciplinary collaboration focused on the region. Training activities will include (1) training of up to 3 PhD students or up to 5 Masters students; (2) support for up to 4 postdoctoral fellows and 11 visiting faculty fellows promoting the development of junior and mid-career faculty; (3) annual workshops and periodic webinars and journal clubs on social determinants of health, CVD and lifecourse epidemiology, and research methods; (4) support for the development of data management and analytical capacity on site; and (5) enhanced south-south collaborations in mentorship and research. As a result of the program we expect to see an increase in the number researchers with Masters or Doctoral degrees at INCAP, an increase in the number of publications and grant proposals submitted by local researchers, larger numbers of mentoring relationships, publications, and grant proposals involving collaborations between INCAP and other countries in the region, greater capacity for data management/analysis at INCAP, and greater engagement of local investigators in CVD research and dissemination activities, including policy translation in the region. We also expect to see a continuation proposal to this training program submitted by INCAP as lead at the end of the this initial phase of the program.

项目摘要 在过去的几十年里，心血管疾病（CVD）的发病率和CVD危险因素的患病率 在中美洲区域，这一数字稳步上升，与美洲其他国家形成鲜明对比， CVD不再增加或下降。该地区CVD的上升与以下因素同时发生： 城市化的加剧和社会不平等的扩大，给其有限的经济带来了越来越大的、难以承受的负担。 公共卫生和医疗保健系统。虽然高收入国家的研究突出了对以下方面的干预： 健康的社会决定因素作为预防心血管疾病的杠杆，对具体的， 可干预的社会决定因素可以帮助预防中美洲的心血管疾病。培训辅导 当地劳动力在确定相关的研究问题，在使用适当的研究方法，并在 向科学界、公众和政策制定者传播研究结果对于确定和 制定干预措施，以预防该地区的心血管疾病。为此，来自德雷克塞尔大学和 中美洲和巴拿马营养研究所（INCAP）合作建立了一个培训计划， 重点是发展受训人员的研究能力和地方在执行政策方面的能力建设， 社会决定因素和基于地点的因素对心血管疾病风险影响的相关研究， 寿命关键要素包括：（1）关注多个层面的因素（从城市到社区， （2）使用严格的最先进的方法;（3）强调价值 （4）传播研究成果并将其转化为政策行动。 该计划利用SALURBAL研究，这是一项专注于该地区的独特多学科合作。 培训活动将包括（1）培训最多3名博士生或最多5名硕士生;（2）支持 最多4名博士后研究员和11名客座教授研究员，促进初级和中级职业发展 教师;（3）年度研讨会和定期网络研讨会和期刊俱乐部对健康的社会决定因素，心血管疾病 （4）支持发展数据管理， 现场分析能力;以及（5）加强在指导和研究方面的南南合作。作为 该计划的结果，我们预计将看到硕士或博士研究人员的数量增加 在INCAP学位，出版物的数量增加，并提出赠款建议，由当地 研究人员，大量的指导关系，出版物，以及涉及 INCAP和该地区其他国家之间的合作，更大的数据能力 INCAP的管理/分析，以及当地研究者更多地参与CVD研究， 传播活动，包括该区域的政策翻译。我们还希望看到 INCAP在该计划初始阶段结束时作为牵头机构提交的该培训计划提案。