Social determinants of cardiovascular disease risk over the life course

项目总结 在过去的几十年里，心血管疾病(CVD)的发病率和心血管疾病危险因素的流行 在中美洲地区稳步增长。该地区心血管疾病的上升是同步发生的。 不断扩大的社会不平等阻碍了实现卫生公平的进展，并构成了一个日益增长的、站不住脚的 其有限的公共卫生和医疗保健系统的负担。培训和指导当地劳动力 确定相关研究问题，使用适当的研究方法，并进行传播 向科学界、公众和政策制定者传达成果对于确定和发展 预防该区域心血管疾病的干预措施。重要的是，包括人们的不同观点 通过增加研究人员和中美洲人的多样性，满足最大的卫生需求 有代表的机构增加了所有人口的健康需求得到满足的可能性，以及 不平等现象减少了。为此，来自德雷克塞尔大学和中环营养研究所的研究人员 美国和巴拿马(INCAP)已经建立了一个D43培训计划，重点是发展研究 受训人员的能力和地方能力建设在开展与政策有关的研究方面的影响 社会决定因素和基于地点的因素对终生心血管疾病风险的影响。拟议的行政管理 补充部分将扩展现有的家长培训计划，以包括两个合作机构 在研究中代表性不足的人群。本补充计划的培训活动利用 由家长培训计划创建的培训基础设施，将包括对博士后研究员的支持 和三名初级学者，以及面向方法的讲习班，以提高受训者的分析能力。这些 这些活动最终将加强新的培训伙伴的机构研究能力， 通过提高INCAP参与强有力的南南合作的潜力，增强其协同研究能力 合作。也就是说，通过帮助巩固加强南南合作的基础 INCAP和中美洲的两个伙伴机构，这一行政补编的培训目标 将帮助INCAP加强其在服务不足的土著和农村地区预防心血管疾病方面的研究 人口。因此，培训方案将有助于发展强有力和可持续的研究 解决健康不平等问题并满足中美洲所有人口的健康需求的能力 通过增加研究队伍的多样性。

PROJECT SUMMARY Over the last several decades, cardiovascular disease (CVD) incidence and the prevalence of CVD risk factors have steadily increased in the Central American region. The rise of CVD in the region has occurred in tandem with widening social inequities that hamper progress toward health equity, and pose a growing, untenable burden for its limited public health and health care systems. Training and mentoring the local workforce in identifying relevant research questions, in the use of appropriate research methods, and in the dissemination of results to the scientific community, the public, and policy makers is critical to identify and develop interventions to prevent CVD in the region. Importantly, including diverse perspectives of the very populations with greatest health needs, through increasing the diversity of the research workforce and Central American institutions represented, increases the probability that the health needs of all populations are addressed and inequities are reduced. To this end, researchers from Drexel University and the Institute for Nutrition of Central America and Panama (INCAP) have established a D43 training program focused on developing the research capabilities of trainees and local capacity building in the conduct of policy-relevant research on the influence of social determinants and place-based factors on CVD risk across the lifespan. The proposed administrative supplement will extend the existing parent training program to include two partner institutions that work populations that have been underrepresented in research. Training activities for the supplement leverage the training infrastructure created by the parent training program and will include support for a postdoctoral fellow and three junior scholars, and methods-oriented workshops to increase analytical capacity of trainees. These activities will ultimately strengthen the institutional research capacity of new training partners, and, synergistically research capacity at INCAP by increasing its potential to engage in robust south-south collaborations. That is, by helping to solidify the foundation for increased south-south collaboration between INCAP and two partner institutions from Central America, the training goals of this administrative supplement will help INCAP strengthen its research on in CVD prevention among underserved indigenous and rural populations. Thus, the training program will contribute to developing a strong and sustainable research capacity that addresses health inequities and meets the health needs of all populations within Central America through increasing the diversity of the research workforce.