Research Training in Environmental Toxicology

摘要 在此次Ruth L.Kirschstein NRSA院校研究培训补助金申请的竞争性续签中， 我们申请资金支持加州大学的环境毒理学研究培训 里弗塞德。拟议的跨学科研究培训方案建立在以下坚实的基础上： 现有的环境毒理学研究生课程结构。十八戒是 来自生物医学科学部以及化学、生物化学、植物学和 植物科学、MCSB(分子、细胞和系统生物学)和环境科学。他们一直都是 非常积极地参与环境毒理学的博士后和博士后培训，以及他们的研究 项目资金充足。这些教员的研究项目包括遗传毒理学。 和表观遗传学、分析化学和蛋白质组学、发育毒理学、内分泌干扰和 新陈代谢。博士前实习生将从参与的化学和环境 毒理学研究生课程。成立了一个内部指导委员会来挑选受训人员并监督 学员的进展情况，还任命了一个外部咨询委员会来协助管理培训 程序。每年共招收9名实习生(博士前7名，博士后2名)。实习生将是 接触到涉及纳米制造领域各种尖端技术的多学科研究， 基因组学、蛋白质组学、代谢组学等。继续资助这项研究培训补助金的请求是 以拟议的研究培训与环境健康的相关性为理由，出色的培训 环境，导师精湛的培训经验，强烈的制度承诺，多样化 大学的研究生团体，以及我们在招聘、任命和培养 受训人员在过去两个供资周期中取得的成功。

ABSTRACT In this competitive renewal of the Ruth L. Kirschstein NRSA Institutional Research Training Grant Application, we request funds to support the research training in environmental toxicology at the University of California Riverside. The proposed interdisciplinary research training program is built upon the solid foundation of the existing curriculum structure of the environmental toxicology graduate program. The eighteen preceptors are from the Division of Biomedical Sciences as well as the Departments of Chemistry, Biochemistry, Botany and Plant Science, MCSB (Molecular, Cell and Systems Biology), and Environmental Sciences. They have been very actively engaged in training pre- and postdoctoral individuals in environmental toxicology, and their research projects have been well funded. The research programs of these faculty members include genetic toxicology and epigenetics, analytical chemistry and proteomics, developmental toxicology, and endocrine disruption and metabolism. Pre-doctoral trainees will be selected from the participating Chemistry and Environmental Toxicology graduate programs. An Internal Steering Committee is established to select trainees and monitor progress of trainees, and an External Advisory Board is also named to assist the management of the training program. A total of 9 trainees per year (7 pre-doctorates + 2 postdoctorates) are requested. The trainees will be exposed to multi-disciplinary research involving a variety of cutting-edge technologies in nanofabrication, genomics, proteomics, metabolomics, etc. The request for continued funding of this research training grant is justified by the relevance of the proposed research training to environmental health, the excellent training environment, the superb training experience of the preceptors, the strong institutional commitment, the diverse graduate student body at the University, as well as our success in recruiting, appointing and nurturing the success of trainees in the last two funding cycles.