P30-Core Grant for Vision Research Core C

生物统计和生物信息学(生物分析)核心的总体目标是提高质量，以及 增加NEI-R01持有者在亚特兰大(AVRC)进行的研究数量。这是通过 更好、更快的生物统计学和信息学方法，而不是那些典型的PI自己可以进行的方法 没有核心支持。生物分析工作人员受益于生物统计学方面的正式严格数学培训 和用于解释实验结果的信息学，因此NEI-R01 PI不需要那么多 生物统计学和信息学培训，以有效地设计实验和解释结果。《生物分析》 核心： 1.与NEIR01相比，提供了更好的资源和更方便地访问最先进的分析工具 PI可以单独提供或支持。 2.与私人投资经理协商，以确定项目范围、时间范围和所需服务。 3.开展原本需要雇用生物信息学和生物统计专家的工作，即 对于R01预算来说，这是不切实际的。 4.酌情为绩效指标和人员提供培训，以执行更多的日常任务。 5.对前沿技术的数据和软件进行预测试和故障排除，避免重复错误 由多个单独的PI。 这些目标有助于最大限度地利用每个R01实验，并使其他实验成为可能 无法进行或分析。生物分析核心利用并促进大学水平的使用 来自组成AVRC的五个机构的资源和人才。

The overall goals of the Biostatistics and Bioinformatics (Bioanalysis) Core are to improve the quality, and increase the quantity of research conducted by NEI-R01 holders in the Atlanta (AVRC). This is done through better and faster biostatistics and informatics approaches than those that the typical PI can conduct by himself without Core support. The Bioanalysis staff benefits from formal rigorous mathematical training in biostatistics and informatics for interpretation of experimental results, so that NEI-R01 PIs do not need as much biostatistics and informatics training to effectively design experiments and interpret results. The Bioanalysis Core: 1. Provides better resources and more convenient access to state of the art analysis tools than an NEIR01 PI could provide or support alone. 2. Consults with PIs to determine scope of a project, timeframe, services needed. 3. Conducts work that would otherwise require hiring of bioinformatics and biostatistics experts that is impractical for an R01 budget. 4. Provides training to PIs and personnel as appropriate for more routine tasks. 5. Pre-tests and troubleshoots data and software from bleeding edge technologies to avoid repeated mistakes by multiple individual PIs. These Aims serve to maximize the utility of each R01 experiment and enables experiments that otherwise could not be conducted or analyzed. The Bioanalysis Core leverages and facilitates usage of university level resources and talents from among the five institutions that make up the AVRC.