Core A - Administrative and Biostatistics Core

核心 A - 行政和生物统计核心

• 批准号: 10493658
• 负责人: Anil K Rustgi
• 金额: $ 13.81万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2021-07-02
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10493658
• 关键词: Core; Administrative; Biostatistics

PROJECT SUMMARY – CORE A The Administrative and Biostatistics Core (referred to as Core A). Core A has two interrelated components: Administrative and Biostatistics, which serve to advance the missions of the P01 that are not able to be served by other entities. The overriding objectives or Specific Aims of the Administrative component, under the direction of Dr. Anil Rustgi (also overall Director of Core A), is to coordinate an integrated research program between the Projects and with strong support from the scientific Cores. This Administrative component also facilitates interactions with Penn's Perelman's School of Medicine, its NCI designated Abramson Cancer Center, external institutions, enrichment programs, career development pathways, catalyzes new directions for our P01, and ensures that the P01 has the unequivocal and wholehearted institutional support. The Biostatistics component, under the direction of Dr. Qi Long, Professor of Biostatistics, is located in the Penn Center for Clinical Epidemiology and Biostatistics (CCEB). Its objectives or Specific Aims are to provide comprehensive support for the Projects in experimental design, statistical modeling/analysis, data interpretation and methodological investigations. In aggregate, this Core enables innovative basic science research with translation of robust preclinical models into new perspectives in therapeutics of esophageal cancer, which is a major gap in the field.

项目摘要 - 核心A行政和生物统计学核心（称为核心A）。核心A有两个相互关联的组成部分：行政和生物统计学，这些组件有助于推进其他实体无法执行的P01任务。在Anil Rustgi博士（也是Core A的总统总监）的指导下，行政组成部分的压倒性对象或特定目标是协调项目之间的综合研究计划，并在科学核心的强烈支持下。该行政组成部分还促进了与Penn的Perelman医学院的互动，其NCI指定的Abramson癌症中心，外部机构，丰富计划，职业发展途径，为我们的P01催化新的方向，并确保P01具有明确的和全心全意的机构支持。生物统计学教授Qi Long博士在宾夕法尼亚州临床流行病学与生物统计学中心（CCEB）的指导下。它的目标或特定目的是为实验设计，统计建模/分析，数据解释和方法学研究中的项目提供全面的支持。总体而言，该核心可以通过将强大的临床前模型转化为食管癌治疗的新观点，这是该领域的主要差距。