Core A - Administrative and Biostatistics Core

核心 A - 行政和生物统计核心

• 批准号: 10493658
• 负责人: Anil K Rustgi
• 金额: $ 13.81万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2021-07-02
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10493658
• 关键词: Core; Administrative; Biostatistics

PROJECT SUMMARY – CORE A The Administrative and Biostatistics Core (referred to as Core A). Core A has two interrelated components: Administrative and Biostatistics, which serve to advance the missions of the P01 that are not able to be served by other entities. The overriding objectives or Specific Aims of the Administrative component, under the direction of Dr. Anil Rustgi (also overall Director of Core A), is to coordinate an integrated research program between the Projects and with strong support from the scientific Cores. This Administrative component also facilitates interactions with Penn's Perelman's School of Medicine, its NCI designated Abramson Cancer Center, external institutions, enrichment programs, career development pathways, catalyzes new directions for our P01, and ensures that the P01 has the unequivocal and wholehearted institutional support. The Biostatistics component, under the direction of Dr. Qi Long, Professor of Biostatistics, is located in the Penn Center for Clinical Epidemiology and Biostatistics (CCEB). Its objectives or Specific Aims are to provide comprehensive support for the Projects in experimental design, statistical modeling/analysis, data interpretation and methodological investigations. In aggregate, this Core enables innovative basic science research with translation of robust preclinical models into new perspectives in therapeutics of esophageal cancer, which is a major gap in the field.

项目摘要--核心A行政和生物统计核心(简称核心A)。核心A有两个相互关联的组成部分：行政和生物统计，这两个组成部分有助于推进P01的任务，而这些任务是其他实体无法完成的。在Anil Rustgi博士(也是核心A的总主任)的指导下，行政部门的首要目标或具体目标是在科学核心的大力支持下，协调项目之间的综合研究计划。该行政部门还促进了与宾夕法尼亚大学佩雷尔曼医学院、NCI指定的艾布拉姆森癌症中心、外部机构、充实计划、职业发展路径的互动，促进了我们P01的新方向，并确保P01获得明确和全心全意的机构支持。生物统计学部分由生物统计学教授齐龙博士指导，位于宾夕法尼亚大学临床流行病学和生物统计中心(CCEB)。其目标或具体目的是在实验设计、统计建模/分析、数据解释和方法学调查方面为项目提供全面支持。总体而言，这一核心使创新的基础科学研究成为可能，将强大的临床前模型转化为食道癌治疗的新视角，这是该领域的一个主要空白。