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Southeast Collaborative for Innovative and Equitable Solutions to Chronic Disease Disparities

东南合作以创新和公平的方式解决慢性病差异

基本信息

批准号：
10494158
负责人：
Nancy J Cox
金额：
$ 247.46万
依托单位：
VANDERBILT UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-24 至 2026-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10494158
关键词：
Academic Medical Centers Address African American African American population Asthma Award Behavioral Bioinformatics Biological Black Populations Black race Cardiovascular Diseases Cause of Death Cessation of life Chronic Chronic Disease Clinical Collaborations Communities Community Health Aides Complex Coping Behavior Data Data Science Decision Making Dentists Diabetes Mellitus Disadvantaged minority Discipline Discrimination Doctor of Philosophy Environment Faculty Fostering Genetic Glycosylated hemoglobin A Health Health Disparities Research Health Expenditures Health Insurance Health Professional Health Services Accessibility Health system Hispanic Home Human Hypertension Individual Infrastructure Institutes Institution International Intervention Latino Latino Population Lead Link Malignant Neoplasms Medicine Mentors Minority Obesity Operative Surgical Procedures Outcome Patients Personal Satisfaction Physicians Policies Population Poverty Prevention Psyche structure Quality of life Research Research Personnel Research Training Resources Risk Risk Factors Rural Community Science Scientist Secure Services Sleep Social Work Social support Socioeconomic Status Southeastern United States Stephania Structural Racism Structure Technology Testing Time Tobacco use Training Trauma United States Public Health Service Universities Urban Community Vascular Diseases adaptive intervention career development community center community intervention coping mechanism data harmonization design diabetes management disease disparity diverse data ethnic health disparity ethnic minority experience family support genomic data health data health disparity health equity health inequalities implementation science improved innovation mHealth medical schools novel personalized medicine phenotypic data population health premature prevent preventable death professional atmosphere professor programs racial and ethnic racial minority racism social social health determinants

项目摘要

The burden of racial and ethnic health disparities is most evident in the southeastern United States, where Black and Latino populations suffer the highest rates of cardiovascular disease, diabetes, obesity, hypertension, cancer, and asthma. These chronic conditions are a primary cause of poor health, reduced quality of life, and premature death, and account for more than 50% of health care expenditures. Despite substantial reduction of some chronic diseases and risk factors over the last few decades, the Southeast continues to have the highest number of potentially preventable deaths for each of the five leading causes of death. Racial and ethnic minorities comprise 39% of the population of the Southeast (HHS Region IV), which includes nearly 15 million African Americans and 9 million Latinos. Minorities in the Southeast fare worse on many health indicators compared to other regions, in large part due to poor socioeconomic status, with more than 22% of Southeastern residents living in poverty. Effectively addressing pervasive chronic disease disparities will require interventions that consider the needs, priorities, and lived experiences of those disproportionately impacted. Research teams with expertise in social, environmental, behavioral, and biological disciplines must collaborate to develop and test multicomponent strategies aimed at the multilevel determinants that drive disparities. Via a new center - the Southeast Collaborative for Innovative and Equitable Solutions to Chronic Disease Disparities, we will bring together Vanderbilt University Medical Center, University of Miami, and Meharry Medical College to address to reduce risk factors for and disparities in diabetes, cardiovascular disease, obesity, and related conditions among African American and Latino populations in the Southeast. We aim to: Specific Aim 1: Establish the human and technical infrastructure to foster highly collaborative, transdisciplinary research collaborations focused on using technology and data science to reduce chronic disease disparities among African American and Latino populations in the southeastern United States. Specific Aim 2: Facilitate a regional, cross-institutional pilot awards program focused on chronic disease disparities that nurtures and supports career development, advances use of data science, technology, and bioinformatics to address the complex drivers of health disparities, and promotes inclusive excellence. Specific Aim 3: Propel novel health disparities research leveraging technology, individual-level and community- level social determinants of health data, and genomic and phenotypic data to prevent, treat, and manage diabetes, cardiovascular disease, obesity and related conditions in African American and Latino populations. Specific Aim 4: Partner with African American and Latino communities in the Southeast integrate their priorities into the Center’s infrastructure, and collaboratively develop, adapt, and test socially and culturally appropriate interventions to secure the earliest impact on eliminating chronic disease disparities.

种族和民族健康差异的负担在美国东南部最为明显，那里黑人和拉丁裔人群患心血管疾病、糖尿病、肥胖、高血压、癌症和哮喘。这些慢性病是导致健康状况不佳、生活质量下降和过早死亡，占医疗保健支出的 50% 以上。尽管大幅减少过去几十年来，东南部地区的一些慢性病和危险因素仍然是最高的五种主要死因中每一种的潜在可预防死亡人数。少数民族人口占东南部（HHS 第四区）人口的 39%，其中包括近 1500 万非裔美国人和 900 万拉丁裔美国人。东南部少数族裔的健康状况较差与其他地区相比，这在很大程度上是由于社会经济地位较差，超过22% 东南部居民生活贫困。有效解决普遍存在的慢性病差异需要干预措施考虑到那些受到不成比例影响的人的需求、优先事项和生活经历。具有社会、环境、行为和生物学科专业知识的研究团队必须合作制定和测试针对造成差异的多层次决定因素的多组成部分战略。通过一个新中心 - 慢性病创新和公平解决方案东南合作组织疾病差异，我们将汇集范德比尔特大学医学中心、迈阿密大学和梅哈里医学院致力于减少糖尿病、心血管疾病、东南部非裔美国人和拉丁裔人群的肥胖及相关状况。我们的目标是：具体目标 1：建立人力和技术基础设施，以促进高度协作、跨学科研究合作的重点是利用技术和数据科学来减少慢性病差异美国东南部的非裔美国人和拉丁裔人口中。具体目标 2：促进专注于慢性病的区域性、跨机构试点奖励计划培养和支持职业发展、促进数据科学、技术和技术的使用的差异生物信息学解决健康差异的复杂驱动因素，并促进包容性卓越。具体目标 3：利用技术、个人层面和社区推动新型健康差异研究确定健康数据以及基因组和表型数据的社会决定因素，以预防、治疗和管理非裔美国人和拉丁裔人群的糖尿病、心血管疾病、肥胖症和相关疾病。具体目标 4：与东南部的非裔美国人和拉丁裔社区合作，整合他们的优先事项融入中心的基础设施，并协作开发、适应和测试适合社会和文化的采取干预措施，以确保尽早对消除慢性病差异产生影响。