Southeast Collaborative for Innovative and Equitable Solutions to Chronic Disease Disparities

东南合作以创新和公平的方式解决慢性病差异

• 批准号: 10494158
• 负责人: Nancy J Cox
• 金额: $ 247.46万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-24 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10494158
• 关键词: Academic Medical Centers; Address; African American; African American population; Asthma; Award; Behavioral; Bioinformatics; Biological; Black Populations; Black race; Cardiovascular Diseases; Cause of Death; Cessation of life; Chronic; Chronic Disease; Clinical; Collaborations; Communities; Community Health Aides; Complex; Coping Behavior; Data; Data Science; Decision Making; Dentists; Diabetes Mellitus; Disadvantaged minority; Discipline; Discrimination; Doctor of Philosophy; Environment; Faculty; Fostering; Genetic; Glycosylated hemoglobin A; Health; Health Disparities Research; Health Expenditures; Health Insurance; Health Professional; Health Services Accessibility; Health system; Hispanic; Home; Human; Hypertension; Individual; Infrastructure; Institutes; Institution; International; Intervention; Latino; Latino Population; Lead; Link; Malignant Neoplasms; Medicine; Mentors; Minority; Obesity; Operative Surgical Procedures; Outcome; Patients; Personal Satisfaction; Physicians; Policies; Population; Poverty; Prevention; Psyche structure; Quality of life; Research; Research Personnel; Research Training; Resources; Risk; Risk Factors; Rural Community; Science; Scientist; Secure; Services; Sleep; Social Work; Social support; Socioeconomic Status; Southeastern United States; Stephania; Structural Racism; Structure; Technology; Testing; Time; Tobacco use; Training; Trauma; United States Public Health Service; Universities; Urban Community; Vascular Diseases; adaptive intervention; career development; community center; community intervention; coping mechanism; data harmonization; design; diabetes management; disease disparity; diverse data; ethnic health disparity; ethnic minority; experience; family support; genomic data; health data; health disparity; health equity; health inequalities; implementation science; improved; innovation; mHealth; medical schools; novel; personalized medicine; phenotypic data; population health; premature; prevent; preventable death; professional atmosphere; professor; programs; racial and ethnic; racial minority; racism; social; social health determinants

The burden of racial and ethnic health disparities is most evident in the southeastern United States, where Black and Latino populations suffer the highest rates of cardiovascular disease, diabetes, obesity, hypertension, cancer, and asthma. These chronic conditions are a primary cause of poor health, reduced quality of life, and premature death, and account for more than 50% of health care expenditures. Despite substantial reduction of some chronic diseases and risk factors over the last few decades, the Southeast continues to have the highest number of potentially preventable deaths for each of the five leading causes of death. Racial and ethnic minorities comprise 39% of the population of the Southeast (HHS Region IV), which includes nearly 15 million African Americans and 9 million Latinos. Minorities in the Southeast fare worse on many health indicators compared to other regions, in large part due to poor socioeconomic status, with more than 22% of Southeastern residents living in poverty. Effectively addressing pervasive chronic disease disparities will require interventions that consider the needs, priorities, and lived experiences of those disproportionately impacted. Research teams with expertise in social, environmental, behavioral, and biological disciplines must collaborate to develop and test multicomponent strategies aimed at the multilevel determinants that drive disparities. Via a new center - the Southeast Collaborative for Innovative and Equitable Solutions to Chronic Disease Disparities, we will bring together Vanderbilt University Medical Center, University of Miami, and Meharry Medical College to address to reduce risk factors for and disparities in diabetes, cardiovascular disease, obesity, and related conditions among African American and Latino populations in the Southeast. We aim to: Specific Aim 1: Establish the human and technical infrastructure to foster highly collaborative, transdisciplinary research collaborations focused on using technology and data science to reduce chronic disease disparities among African American and Latino populations in the southeastern United States. Specific Aim 2: Facilitate a regional, cross-institutional pilot awards program focused on chronic disease disparities that nurtures and supports career development, advances use of data science, technology, and bioinformatics to address the complex drivers of health disparities, and promotes inclusive excellence. Specific Aim 3: Propel novel health disparities research leveraging technology, individual-level and community- level social determinants of health data, and genomic and phenotypic data to prevent, treat, and manage diabetes, cardiovascular disease, obesity and related conditions in African American and Latino populations. Specific Aim 4: Partner with African American and Latino communities in the Southeast integrate their priorities into the Center’s infrastructure, and collaboratively develop, adapt, and test socially and culturally appropriate interventions to secure the earliest impact on eliminating chronic disease disparities.

种族和民族健康差异的负担在美国东南部最为明显， 黑人和拉丁美洲人患心血管疾病、糖尿病、肥胖症、高血压的比率最高， 癌症和哮喘这些慢性病是健康状况不佳、生活质量下降以及 过早死亡，占医疗保健支出的50%以上。尽管大幅度减少 在过去的几十年里，一些慢性疾病和危险因素，东南部仍然是最高的 五个主要死因中每一个的潜在可预防死亡人数。 种族和少数民族占东南部（HHS第四区）人口的39%，其中包括 近1500万非洲裔美国人和900万拉丁裔美国人。东南部的少数民族在许多健康状况上更差 与其他地区相比，这在很大程度上是由于社会经济状况差，22%以上的 生活在贫困中的东南部居民。有效解决普遍存在的慢性病差异需要 干预措施考虑到不成比例地受到影响的人的需求，优先事项和生活经历。 具有社会、环境、行为和生物学科专业知识的研究团队必须合作 制定和测试针对造成差距的多层次决定因素的多成分战略。 通过一个新的中心-东南合作创新和公平的解决方案，以慢性 疾病差异，我们将汇集范德比尔特大学医学中心，迈阿密大学， 梅哈里医学院致力于减少糖尿病、心血管疾病、 肥胖症，以及东南部非洲裔美国人和拉丁裔人口的相关状况。我们的目标是： 具体目标1：建立人力和技术基础设施，以促进高度协作、跨学科 研究合作侧重于利用技术和数据科学来减少慢性病的差异 在美国东南部的非洲裔美国人和拉丁裔人口中。 具体目标2：促进区域性、跨机构的试点奖励计划，重点关注慢性病 促进和支持职业发展的差距，促进数据科学，技术的使用， 生物信息学解决健康差距的复杂驱动因素，并促进包容性卓越。 具体目标3：利用技术、个人和社区推动新的健康差距研究- 健康数据的社会决定因素以及预防、治疗和管理的基因组和表型数据 糖尿病、心血管疾病、肥胖症及相关疾病。 具体目标4：与东南部的非洲裔美国人和拉丁裔社区合作，整合他们的优先事项 纳入中心的基础设施，并协同开发，适应和测试社会和文化上合适的 采取干预措施，确保尽早消除慢性病差距。