Administrative Core

行政核心

• 批准号: 10494255
• 负责人: Michael Isaac Goran
• 金额: $ 103.05万
• 依托单位: CHILDREN'S HOSPITAL OF LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-24 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10494255
• 关键词: 5 year old; Achievement; Address; Advisory Committees; Advocacy; Affect; Behavior Therapy; Behavioral; Benchmarking; Biological; Biometry; Birth; California; Child; Chronic; Chronic Disease; Clinical; Clinical Informatics; Cohort Studies; Collaborations; Colorado; Communities; Complex; Data; Development; Dietary intake; Dyslipidemias; Elderly; Ensure; Environmental Risk Factor; Evaluation; Family; Feedback; Fostering; Generations; Goals; Government; Household; Individual; Intervention; Knowledge; Latino; Latino Population; Leadership; Life; Los Angeles; Measures; Mentors; Methodology; Methods; Non-Insulin-Dependent Diabetes Mellitus; Nutritional; Obesity; Parents; Pediatric Hospitals; Phenotype; Pilot Projects; Policies; Prevention; Prevention strategy; Program Evaluation; Research; Research Methodology; Research Personnel; Research Project Grants; Research Training; Resources; Risk Reduction; Science; Specialized Center; Structure; System; Testing; Translational Research; Underrepresented Populations; Universities; Vision; Work; base; career development; community engagement; data harmonization; data management; data quality; disorder risk; effectiveness evaluation; environmental intervention; health disparity; meetings; minority health disparity; non-alcoholic fatty liver disease; obesity treatment; outreach; programs; response; social factors; social health determinants; success; synergism; treatment effect; treatment program

The overall goal of the Southern California Center for Chronic Health Disparities in Latino Families and Children (SCC-CHDLFC) is to establish a regional coalition of academic, clinical, government and community stakeholders to address the co-occurring disparities in obesity, type 2 diabetes, non-alcoholic fatty liver disease, and dyslipidemia that are disproportionally affecting Latinos in our region with a focus on addressing early life determinants and family-based strategies for prevention and treatment. The SCC-CHDLFC is a comprehensive and inclusive regional coalition of individuals and organizations that builds on existing collaborations and leverages numerous resources. This coalition will provide the necessary expertise and support to advance understanding, prevention, and treatment of the multilevel behavioral, nutritional, biological, inter-personal, social, and environmental factors that contribute to vulnerabilities for these chronic conditions among Latinos. The overall goal of the Administrative Core is to ensure the success, scientific rigor, and regional and societal impact of the Center. The Core will be led by Drs. Goran (CHLA) and Baezconde-Garbanati (USC) who provide complementary expertise in clinical/translational research in Latinos and community engagement and have a track record of working together leading mulit-investigator Centers related to minority health and health disparities. The Core will be responsible for structuring, initiating, maintaining, and coordinating all Center activities to ensure that goals are met, including scientific progress, developing a diverse pool of young investigators, program evaluation, and influencing lasting changes at the community and system levels, through 3 Specific Aims. Aim 1 is to provide overall leadership and vision as well as scientific, fiscal, and administrative oversight. This oversight will ensure scientific rigor and maximize interaction between Center cores, research projects, and pilot studies to ensure integrated efforts in research, training, career development, and community engagement are met, that team science strategies are utilized, and that trans-disciplinary opportunities are maximized. Aim 2 is to ensure data quality and harmonization by providing high-level methodological expertise to the projects and pilot studies through a Methods and Data Sub-Core. By leveraging existing Research Cores, we will provide efficient and rigorous Center-wide expertise in biostatistics, data management and and assessment of social determinants of health, dietary intake, and geospatial factors. This will accelerate and promote transdisciplinary research, integration, and synergy across our Center and the P50 program. Aim 3 is to conduct ongoing program evaluation to guide the progress and impact of the Center, with a feedback loop for Center improvements to ensure the Center stays on track and meets its objectives. Ongoing and systematic evaluation will determine progress towards aims within each project and core, and achievement of milestones and benchmarks of the projects, cores, and pilot studies, as well as evaluating the effectiveness of interaction between Center components, investigator development, and meeting outreach and engagement objectives.

南加州南加州慢性健康差异的总体目标 儿童（SCC-CHDLFC）是建立一个学术，临床，政府和 社区利益相关者解决肥胖症，2型糖尿病，非酒精脂肪的共同发生差异 肝病和血脂异常，对我们地区的拉丁美洲人不成比例，重点 解决早期生命决定因素和基于家庭的预防和治疗策略。 SCC-CHDLFC 是一个由个人和组织组成的全面而包容的区域联盟，以现有 协作和利用众多资源。该联盟将提供必要的专业知识和 支持促进对多层次行为，营养，生物学，预防和治疗的理解，预防和治疗 有助于这些慢性条件的脆弱性的人际关系，社会和环境因素 在拉丁美洲人中。行政核心的总体目标是确保成功，科学严谨和区域 和中心的社会影响。核心将由博士领导。 Goran（CHLA）和Baezconde-Garbanati（USC） 在拉丁裔和社区参与方面提供互补的专业知识 并具有与少数民族健康有关的领先的MULIT投资者中心共同努力的记录 健康差异。核心将负责结构，启动，维护和协调所有中心 确保实现目标的活动，包括科学进步，发展各种各样的年轻人 调查人员，计划评估以及通过 3个具体目标。目标1是提供整体领导和愿景以及科学，财政和行政 监督。这种疏忽将确保科学严格并最大程度地提高中心核之间的相互作用，研究 项目和试点研究，以确保在研究，培训，职业发展和社区中综合努力 达到了参与，利用了团队科学策略，跨学科的机会是 最大化。 AIM 2是通过提供高级方法论专业知识来确保数据质量和协调 通过方法和数据子核心进行项目和试点研究。通过利用现有的研究核心， 我们将在生物统计学，数据管理和 评估健康，饮食摄入和地理空间因素的社会决定因素。这将加速并 在我们的中心和P50计划中促进跨学科研究，整合和协同作用。 AIM 3是 进行正在进行的计划评估以指导中心的进度和影响，并有一个反馈循环 中心的改进，以确保中心保持轨道并达到其目标。正在进行的和系统的 评估将确定每个项目和核心内目标的进步，并实现里程碑 项目，核心和试点研究的基准，以及评估相互作用的有效性 在中心组件，调查员开发以及实现外展和参与目标之间。