Administrative Core

行政核心

• 批准号: 10494255
• 负责人: Michael Isaac Goran
• 金额: $ 103.05万
• 依托单位: CHILDREN'S HOSPITAL OF LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-24 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10494255
• 关键词: 5 year old; Achievement; Address; Advisory Committees; Advocacy; Affect; Behavior Therapy; Behavioral; Benchmarking; Biological; Biometry; Birth; California; Child; Chronic; Chronic Disease; Clinical; Clinical Informatics; Cohort Studies; Collaborations; Colorado; Communities; Complex; Data; Development; Dietary intake; Dyslipidemias; Elderly; Ensure; Environmental Risk Factor; Evaluation; Family; Feedback; Fostering; Generations; Goals; Government; Household; Individual; Intervention; Knowledge; Latino; Latino Population; Leadership; Life; Los Angeles; Measures; Mentors; Methodology; Methods; Non-Insulin-Dependent Diabetes Mellitus; Nutritional; Obesity; Parents; Pediatric Hospitals; Phenotype; Pilot Projects; Policies; Prevention; Prevention strategy; Program Evaluation; Research; Research Methodology; Research Personnel; Research Project Grants; Research Training; Resources; Risk Reduction; Science; Specialized Center; Structure; System; Testing; Translational Research; Underrepresented Populations; Universities; Vision; Work; base; career development; community engagement; data harmonization; data management; data quality; disorder risk; effectiveness evaluation; environmental intervention; health disparity; meetings; minority health disparity; non-alcoholic fatty liver disease; obesity treatment; outreach; programs; response; social factors; social health determinants; success; synergism; treatment effect; treatment program

The overall goal of the Southern California Center for Chronic Health Disparities in Latino Families and Children (SCC-CHDLFC) is to establish a regional coalition of academic, clinical, government and community stakeholders to address the co-occurring disparities in obesity, type 2 diabetes, non-alcoholic fatty liver disease, and dyslipidemia that are disproportionally affecting Latinos in our region with a focus on addressing early life determinants and family-based strategies for prevention and treatment. The SCC-CHDLFC is a comprehensive and inclusive regional coalition of individuals and organizations that builds on existing collaborations and leverages numerous resources. This coalition will provide the necessary expertise and support to advance understanding, prevention, and treatment of the multilevel behavioral, nutritional, biological, inter-personal, social, and environmental factors that contribute to vulnerabilities for these chronic conditions among Latinos. The overall goal of the Administrative Core is to ensure the success, scientific rigor, and regional and societal impact of the Center. The Core will be led by Drs. Goran (CHLA) and Baezconde-Garbanati (USC) who provide complementary expertise in clinical/translational research in Latinos and community engagement and have a track record of working together leading mulit-investigator Centers related to minority health and health disparities. The Core will be responsible for structuring, initiating, maintaining, and coordinating all Center activities to ensure that goals are met, including scientific progress, developing a diverse pool of young investigators, program evaluation, and influencing lasting changes at the community and system levels, through 3 Specific Aims. Aim 1 is to provide overall leadership and vision as well as scientific, fiscal, and administrative oversight. This oversight will ensure scientific rigor and maximize interaction between Center cores, research projects, and pilot studies to ensure integrated efforts in research, training, career development, and community engagement are met, that team science strategies are utilized, and that trans-disciplinary opportunities are maximized. Aim 2 is to ensure data quality and harmonization by providing high-level methodological expertise to the projects and pilot studies through a Methods and Data Sub-Core. By leveraging existing Research Cores, we will provide efficient and rigorous Center-wide expertise in biostatistics, data management and and assessment of social determinants of health, dietary intake, and geospatial factors. This will accelerate and promote transdisciplinary research, integration, and synergy across our Center and the P50 program. Aim 3 is to conduct ongoing program evaluation to guide the progress and impact of the Center, with a feedback loop for Center improvements to ensure the Center stays on track and meets its objectives. Ongoing and systematic evaluation will determine progress towards aims within each project and core, and achievement of milestones and benchmarks of the projects, cores, and pilot studies, as well as evaluating the effectiveness of interaction between Center components, investigator development, and meeting outreach and engagement objectives.

南加州拉丁裔家庭慢性健康差异中心的总体目标 和儿童(SCC-CHDLFC)将建立一个由学术、临床、政府和 社区利益攸关方解决肥胖、2型糖尿病、非酒精性脂肪共同存在的差异 肝病和血脂异常正不成比例地影响着我们区域的拉美裔人，重点是 解决早期生活决定因素和以家庭为基础的预防和治疗战略。SCC-CHDLFC 是建立在现有基础上的个人和组织的全面和包容的地区性联盟 协作，并利用大量资源。这一联盟将提供必要的专业知识和 支持促进对多层次行为、营养、生物学、 导致这些慢性疾病脆弱性的个人、社会和环境因素 在拉丁裔中。行政核心的总体目标是确保成功、科学严谨和地区性 以及该中心的社会影响。核心将由Goran博士(CHLA)和Baezconde-Garbanati博士(南加州大学)领导 在拉丁裔临床/翻译研究和社区参与方面提供补充专业知识 并有与领先的多项研究中心合作的记录，这些中心与少数族裔健康和 健康差距。核心将负责组织、发起、维护和协调所有中心 确保实现目标的活动，包括科学进步，培养多样化的青年群体 调查人员、项目评估，并通过以下方式影响社区和系统层面的持久变化 3具体目标。目标1是提供全面的领导和远见，以及科学、财政和管理 疏忽。这种监督将确保科学的严谨性，并最大限度地提高中心核心、研究 项目和试点研究，以确保在研究、培训、职业发展和社区方面的综合努力 参与度得到满足，团队科学战略得到利用，跨学科的机会得到了 最大化。目标2是通过提供高水平的方法学专门知识来确保数据质量和协调一致 通过一个方法和数据分核心向项目和试点研究提供资金。通过利用现有的研究核心， 我们将提供高效和严谨的全中心生物统计、数据管理和 评估健康、饮食摄入量和地理空间因素的社会决定因素。这将加速并 在我们的中心和P50计划中促进跨学科研究、整合和协同。目标3是 进行持续的计划评估，以指导中心的进展和影响，并为 中心改进，以确保中心保持在正轨上并实现其目标。持续和系统的 评价将决定每个项目和核心目标的进展情况，以及里程碑的实现情况 以及项目、核心和试点研究的基准，以及评价互动的有效性 在中心组成部分、调查员发展以及满足外展和参与目标之间。