Pilot and Feasibility Program

试点和可行性计划

• 批准号: 10512737
• 负责人: JOEL K. ELMQUIST
• 金额: $ 20.5万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10512737
• 关键词: Award; Behavioral; Biological; Collaborations; Communities; Data; Energy Metabolism; Ensure; Evaluation; Faculty; Fostering; Functional disorder; Funding; Funding Agency; Genetic; Goals; Grant; Intervention; Lead; Mentorship; Metabolism; Mission; National Institute of Diabetes and Digestive and Kidney Diseases; Nutrient; Nutritional; Obesity; Obesity associated disease; Output; Physiological; Publications; Research; Research Personnel; Research Support; Resources; Scientist; Techniques; Underrepresented Minority; Woman; career development; comorbidity; disorder risk; energy balance; innovation; member; novel; novel therapeutics; nutrition; outreach; programs; recruit

Abstract/Summary – Pilot & Feasibility Grants Program The UT Southwestern Nutrition and Obesity Research Center (UTSW NORC) Pilot & Feasibility Grants Program (P&F) will foster research on the genetic, physiological, nutritional, and behavioral determinants that regulate energy balance and metabolism. This includes studies investigating the pathophysiology of obesity and the effects of altered composition and quantity of nutrients to impact intermediary metabolism and modulate disease risk. We will also support studies aimed at developing novel interventions to reduce obesity and associated comorbidities. To achieve this goal, we will provide opportunities for both new and established UT Southwestern investigators to generate sufficient preliminary data for a successful application for major research funding from NIDDK or other national granting agencies. The $100K/year for the UTSW NORC P&F grants program will fund up to 4 applications each year. These awards will be important for recruiting and fostering new investigators to the field. We also strongly believe that given the nutrition and obesity research expertise at UT Southwestern, these awards will result in considerable return of new funded NIDDK awards, new collaborations among UTSW NORC members, and most importantly, significant advances in the field that will lead to new therapeutic opportunities.

摘要/总结 - 试点和可行性资助计划 德克萨斯大学西南营养与肥胖研究中心 (UTSW NORC) 试点和可行性资助 计划（P&F）将促进对遗传、生理、营养和行为决定因素的研究， 调节能量平衡和新陈代谢。这包括调查肥胖病理生理学的研究 以及营养成分和数量改变对中间代谢和代谢的影响 调节疾病风险。我们还将支持旨在开发新的干预措施以减少肥胖的研究 以及相关的合并症。为了实现这一目标，我们将为新老企业提供机会 德州大学西南分校的调查人员为成功申请专业生成足够的初步数据 来自 NIDDK 或其他国家资助机构的研究经费。 UTSW NORC P&F 每年 10 万美元 赠款计划每年将为最多 4 份申请提供资助。这些奖项对于招聘和 培养新的调查人员到该领域。我们还坚信，鉴于营养和肥胖研究 UT Southwestern 的专业知识，这些奖项将为新资助的 NIDDK 奖项带来可观的回报， UTSW NORC 成员之间的新合作，最重要的是，该领域取得了重大进展 这将带来新的治疗机会。