精神分裂症的神经网络不稳定可以通过极低碳水化合物的生酮饮食来改善吗？-猫眼课题宝

精神分裂症的神经网络不稳定可以通过极低碳水化合物的生酮饮食来改善吗？

批准号：

10517239

负责人：

Judith M Ford

金额：

$5.97万

依托单位：

NORTHERN CALIFORNIA INSTITUTE/RES/EDU

依托单位国家：

美国

项目类别：

财政年份：

2021

资助国家：

美国

项目状态：

已结题

起止时间：

2021-09-01 至 2023-08-31

来源：

https://reporter.nih.gov/project-details/10517239

关键词：

Acute Adult Age Aging Anhedonia Antipsychotic Agents Body Weight decreased Brain Carbohydrates Chronic Clinical Clinical Research Cognition Cognitive deficits Data Delusions Diagnosis Diet Disease Doctor of Philosophy Eating Educational Curriculum Educational workshop Fatty acid glycerol esters Functional Magnetic Resonance Imaging Functional disorder Glucose Goals Grant Hallucinations Homeostasis Impaired cognition Inflammation Inflammatory Insulin Insulin Resistance Intervention Interview Ketone Bodies Ketones Ketosis Learning Link Lipids Literature Magnetic Resonance Imaging Measures Mediating Mentors Meta-Analysis Metabolic Metabolic Diseases Metabolic syndrome Metabolism Mitochondria Modernization Neurobiology Neurocognitive Deficit Neuropsychology Non-Insulin-Dependent Diabetes Mellitus Nutrient Obesity Occupational Outcome Overweight Paper Participant Patients Peripheral Persons Pharmaceutical Preparations Predisposition Production Randomized Reactive Oxygen Species Reducing diet Reporting Research Rest Risk Role Schizophrenia Symptoms Time Training Visceral fat Weight Gain Work Writing base blood glucose regulation brain dysfunction career development comorbidity deprivation diagnostic criteria experience first episode schizophrenia functional decline glucose metabolism human old age (65+)improved indexing insulin sensitivity ketogenic diet neural network parent grant prevent programs prospective relating to nervous system sex social symptomatic improvement systemic inflammatory response tool

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英文摘要

PROJECT SUMMARY/ABSTRACT This diversity supplement will significantly enhance the research potential of Ms. Zanib Naeem and make her competitive for top-tier PhD programs. Ms. Naeem will be involved in a team project that focuses on the benefits of a ketogenic diet in overweight people with schizophrenia. She will become familiar with an array of tools we use in our studies of the pathophysiology of schizophrenia: structural and functional MRI, neuropsychology, and clinical interviews. She will also participate in the Post-Bac Program for Equity and Learning (PROPEL) curriculum activities, on which the PI (Dr. Ford) serves as a mentor. Through the PROPEL program, Ms. Naeem will both participate in biomedical seminars and have access to career development opportunities, such as grant writing workshops and mock interviews.

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