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Translation Core

翻译核心

基本信息

批准号：
10542354
负责人：
Leonardo Trasande
金额：
$ 44.43万
依托单位：
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-12-17 至 2026-11-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10542354
关键词：
Adolescence Adoption Award Basic Science Center for Translational Science Activities Child Child Development Child Health Clinic Collaborations Communication Communities Conceptions Consolidated Framework for Implementation Research Cost Analysis Country Development Discipline Disease Disparity population Economics Educational workshop Effectiveness of Interventions Environmental Engineering technology Environmental Exposure Environmental Health Environmental Medicine Epidemiology Evidence based intervention Exposure to Faculty Fostering Funding Goals Health Health Policy Hospitals Housing Infrastructure Interruption Intervention Life Cycle Stages Low income Measurement Mentors Mentorship Methods Minority Groups Modeling Muslim religion National Center for Advancing Translational Sciences National Institute of Environmental Health Sciences National Institute on Minority Health and Health Disparities Natural experiment Outcome Pilot Projects Policies Population Population Heterogeneity Prevention Prevention Research Prevention strategy Public Health Practice Quasi-experiment Reach, Effectiveness, Adoption, Implementation, and Maintenance Research Research Design Research Personnel Resources Schools Science Scientist Series Services Testing Time Toxicology Training Translating Translational Research Translations base career community engagement community partnership comparative cost effectiveness design econometrics economic evaluation ethnic diversity evidence base experience faculty mentor hazard health communication health disparity health economics health equity implementation science improved innovation manufacture member mid-career faculty multidisciplinary population health prevent primary care clinic programs repository social disparities successful intervention theories tool translational framework translational health science translational pipeline uptake working group young adult

项目摘要

PROJECT SUMMARY (TRANSLATION CORE) While some progress has been made in translating children’s environmental health (CEH) research from basic research to successful interventions, the pace of uptake and adoption of interventions for widescale impact remains slow, and few interventions have been adapted for minority populations or low-income settings with disproportionate exposure. To achieve higher population-wide impact, CEH researchers require training, mentoring, and collaboration with experts from diverse disciplines to cross the translational bridge and successfully scale evidence-based interventions for maximum impact. The goal of the NYU CEHRT Translation Core is to advance research translation and implementation of evidence-based interventions and policies to prevent and mitigate harms associated with environmental exposures on child development. Our strategy focuses on providing CEH scientists with opportunities to envision and build out translation agendas relevant to their CEH research focus, foster new collaborations, obtain pilot funding to support moving their environmental health research along a translational spectrum as outlined in the NIEHS Translational Research Framework, and receive ongoing technical support and mentoring. Our broad base of members span traditional environmental health disciplines of exposure science, toxicology, environmental medicine and engineering, as well as broader translational fields of community engagement, epidemiology, implementation science, health economics, health communications and health policy. Together, we have built an extremely strong track record of moving across the five rings of research described in the NIEHS translational framework. The Translation Core’s specific aims are to: (1) support new collaborations between CEH researchers, scientists from other fields, practitioners, and community stakeholders; (2) solicit, review, and select 4 one-year pilot projects annually; provide continuous mentorship and technical support to pilot program awardees; (3) disseminate CEH research findings using a repository of translation tools and products (interventions, tools, methods, messages, etc.) for multiple communication channels and multi-sector use; (4) compare cost- effectiveness of different interventions to protect children, and quantify health and economic benefits of reductions in exposure to hazards. Overall, the Translation Core advances environmental health research from discovery to public health practice by fostering important dialogue and collaborations between multiple disciplines, as well as building capacity and expertise among CEH researchers in performing multidisciplinary translational research.

项目摘要（翻译核心）尽管在将儿童环境健康（CEH）研究从基础研究转化为研究成功的干预措施、采取和采用干预措施以产生广泛影响的速度仍然缓慢，针对少数民族人口或低收入环境的干预措施很少不成比例的暴露。为了实现更大的人群影响力，CEH 研究人员需要接受培训，与不同学科的专家进行指导和合作，以跨越转化桥梁成功扩大循证干预措施以产生最大影响。纽约大学 CEHRT 的目标翻译核心是推进研究翻译和基于证据的干预措施的实施预防和减轻环境暴露对儿童发育造成的危害的政策。我们的战略重点是为 CEH 科学家提供设想和制定翻译议程的机会与其 CEH 研究重点相关，促进新的合作，获得试点资金以支持其发展 NIEHS 转化研究中概述的转化范围内的环境健康研究框架，并获得持续的技术支持和指导。我们广泛的会员基础涵盖暴露科学、毒理学、环境医学等传统环境健康学科工程，以及社区参与、流行病学、实施等更广泛的转化领域科学、卫生经济学、卫生传播和卫生政策。我们共同打造了一个极其跨越 NIEHS 翻译框架中描述的五个研究环的良好记录。翻译核心的具体目标是：(1) 支持 CEH 研究人员之间的新合作，其他领域的科学家、从业者和社区利益相关者；（二）征集、审核、评选4名一年期每年试点项目；为试点计划获奖者提供持续的指导和技术支持； (3) 使用翻译工具和产品（干预措施、工具、方法、消息等），供多种通信渠道和多部门使用； (4)比较成本- 保护儿童的不同干预措施的有效性，并量化其健康和经济效益减少接触危险的机会。总体而言，翻译核心推进了环境健康研究通过促进多方之间的重要对话和合作来发现公共卫生实践学科，以及 CEH 研究人员进行多学科研究的能力和专业知识建设转化研究。