Administrative Core

行政核心

• 批准号: 10556889
• 负责人: JENNIFER H ELISSEEFF
• 金额: $ 8.84万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10556889
• 关键词: Adoption; Advisory Committees; Aging; Atlases; Benchmarking; Biological; Cataloging; Collaborations; Communication; Computer Analysis; Data; Data Analyses; Data Coordinating Center; Data Management Resources; Data Set; Data Storage and Retrieval; Development; Ensure; Evaluation; Generations; Goals; Image; Immunology; Institution; Leadership; Length; Longevity; Mus; Procedures; Process; Protocols documentation; Quality Control; Recording of previous events; Reporting; Research Personnel; Site; Specimen; Standardization; Structure; System; Technology; Testing; Tissues; United States National Institutes of Health; Work; analysis pipeline; arm; big data management; computerized data processing; conflict resolution; experience; interest; internal control; meetings; mouse genetics; new technology; operation; programs; response; senescence; sex; single-cell RNA sequencing; tissue mapping

The Administrative Core will provide the governance and coordination structure to spearhead the Atlas generation in the JMN-MSMP. The Administrative Core will coordinate and integrate the Biological Analysis Core (BAC) and Data Analysis Core (DAC), and will ensure harmonization of processes and quality control within the JMN-MSMP and with the SenNet Consortium Organization and Data Coordination Center (CODCC) to provide standardized, high-quality datasets for Atlas generation. The MPIs will engage all key stakeholders in shared governance to ensure that perspectives from all components are considered. This will be achieved through an Executive Committee (EC) consisting of the MPIs, and Core Leaders. The AC will coordinate monthly meetings of the EC to review operations, benchmarks, and metrics for continuous quality improvement; provide a forum to introduce emerging opportunities of interest; and formulate action plans for a coordinated response. Internal and External Advisory Committees will provide regular, expert, arms-length advice on scientific decisions, review progress, and assist with conflict resolution. The Administrative Core will work closely with the NIH program manager and external TMCs and data coordinating centers to communicate processes and datasets. Aim 1. Provide JMN-MSMP interdisciplinary leadership and governance structure. Aim 2. Oversee and Coordinate the Biological Analysis and Data Analysis Cores. Aim 3. Coordinate with other SenNet sites to standardize operations and protocols; and prepare, organize, and maintain JMN-MSMP reports and Atlas development.

行政核心将提供治理和协调结构， JMN-MSMP中的Atlas生成。行政核心将协调和整合 生物分析核心（BAC）和数据分析核心（DAC），并将确保 JMN-MSMP和SenNet联盟内部的流程和质量控制 组织和数据协调中心（CODCC）提供标准化、高质量的 用于生成Atlas的数据集。MPI将让所有关键利益相关者参与共同治理， 确保考虑所有组成部分的观点。这将通过一个 执行委员会（EC）由MPI和核心领导人组成。AC将协调 每月召开EC会议，以审查持续质量的运营、基准和指标 提供一个论坛，介绍新出现的令人感兴趣的机会; 协调应对的行动计划。内部和外部咨询委员会将提供 定期，专家，对科学决策的独立意见，审查进展，并协助 解决冲突。行政核心将与NIH项目经理密切合作， 与外部TMC和数据协调中心进行流程和数据集通信。 目标1.提供JMN-MSMP跨学科的领导和治理结构。 目标2.监督和协调生物分析和数据分析核心。 目标3.与其他SenNet站点协调，以标准化操作和协议;以及 准备、组织和维护JMN-MSMP报告和Atlas开发。